scholarly journals Mycophenolate mofetil for the treatment of refractory auto-immune haemolytic anaemia and auto-immune thrombocytopenia purpura

2002 ◽  
Vol 117 (3) ◽  
pp. 712-715 ◽  
Author(s):  
Jo Howard ◽  
A. Victor Hoffbrand ◽  
H. Grant Prentice ◽  
Atul Mehta
Keyword(s):  
Mycophenolate Mofetil ◽  
Haemolytic Anaemia ◽  
Immune Thrombocytopenia ◽  
Immune Haemolytic Anaemia ◽  
Immune Thrombocytopenia Purpura

scholarly journals A case report of Evans Syndrome

2017 ◽  
Vol 12 (2) ◽  
pp. 88-91
Author(s):  
Muhammad Kamruzzaman ◽  
Mohammad Iqbal Hossain ◽  
MM Shahin Ul Islam ◽  
Khan Mohammad Arif ◽  
Md Towhid Alam ◽  
...  
Keyword(s):  
Haemolytic Anaemia ◽  
Immune Thrombocytopenia ◽  
Oral Prednisolone ◽  
Evans Syndrome ◽  
Methyl Prednisolone ◽  
Antiglobulin Test ◽  
Immune Haemolytic Anaemia ◽  
Immune Neutropenia ◽  
Chronic Course

Evans syndrome is a haematological disorder characterized by the sequential or simultaneous development of direct antiglobulin test (DAT) positive autoimmune haemolytic anaemia (AIHA), immune thrombocytopenia (ITP) and/or immune neutropenia in the absence of a known aetiology. No sex predilection is known. It may occur in all ethnic groups and all ages. This condition generally runs a chronic course and is characterized by frequent exacerbations and remissions. Here we report a case of a female who presented with both acute decompensated anaemia & thrombocytopenia. She received total 5 bags blood within 10 days for correction of anaemia but patients condition was deteriorating. CBC with PBF showed features consistent with immune haemolytic anaemia with thrombocytopenia, marked roulaeux formation and reticulocytosis. Direct Coomb's test (DAT) was positive and Indirect coomb's test was (IAT) negative. Her general condition was improved after injection methyl prednisolone for 3 days followed by oral prednisolone. Follow up CBC showed increased haemoglobin and platelet count without blood transfusion.Faridpur Med. Coll. J. Jul 2017;12(2): 88-91

Haemolytic Anaemia: A Diagnostic Dilemma

2018 ◽  
Vol 2 (01) ◽  
pp. 29-31
Author(s):  
Md. Rezaul Karim Chowdhury ◽  
Mohammad Quamrul Hasan ◽  
Md. Haroon Ur Rashid
Keyword(s):  
Haemolytic Anaemia ◽  
Clinical Suspicion ◽  
Diagnostic Dilemma ◽  
High Clinical Suspicion ◽  
Immune Haemolytic Anaemia

It is sometime difficult to find out the cause of haemolysis in haemolytic anaemia due to inconclusive results of investigation. Diagnosis of immune haemolytic anaemia is often difficult when Coomb’s test is negative. Here we present such a case of fourteen years old girl who presented with haemolytic anaemia with negative Coomb’s test. Due to high clinical suspicion we labelled her as a case of Coomb’s negative immune haemolytic anaemia and she responded well to steroid.

An analysis of outcomes and treatment costs for children undergoing splenectomy for chronic immune thrombocytopenia purpura

2012 ◽  
Vol 47 (8) ◽  
pp. 1537-1541 ◽  
Author(s):  
Natalie R. Gwilliam ◽  
David A. Lazar ◽  
Mary L. Brandt ◽  
Donald H. Mahoney ◽  
David E. Wesson ◽  
...  
Keyword(s):  
Immune Thrombocytopenia ◽  
Treatment Costs ◽  
Immune Thrombocytopenia Purpura ◽  
Chronic Immune Thrombocytopenia

scholarly journals Mycophenolate mofetil therapy for severe immune thrombocytopenia

2015 ◽  
Vol 171 (4) ◽  
pp. 625-630 ◽  
Author(s):  
Alice Taylor ◽  
Lucy Neave ◽  
Shalini Solanki ◽  
John Paul Westwood ◽  
Ilaria Terrinonive ◽  
...  
Keyword(s):  
Mycophenolate Mofetil ◽  
Immune Thrombocytopenia
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