Linear childhood cutaneous lupus erythematosus following blaschko lines

Author(s):  
C Requena ◽  
A Torrelo ◽  
I de Prada ◽  
A Zambrano
2020 ◽  
Vol 13 (6) ◽  
pp. e235498
Author(s):  
Deepika Yadav ◽  
Sujay Khandpur ◽  
Pratik Mohta

A 6-year-old boy presented with dusky erythematous plaques in linear and whorled pattern over limbs and trunk for the past 1 year along with subcutaneous nodule on the left cheek of 3 months duration. He also had Gottron-like and inverse Gottron-like papules on hands. Histology from truncal lesion showed interface dermatitis with superficial and deep perivascular and periappendageal infiltrate suggestive of discoid cutaneous lupus erythematosus (CLE), while biopsy from facial nodule revealed features of lupus panniculitis. The connective tissue disease workup showed only antinuclear antibody positivity (2+, 1:100 dilution). There was no clinical or investigational evidence of myositis as part of dermatomyositis (DM) workup. A final diagnosis of Blaschko-linear CLE was made, since Gottron-like and inverse Gottron-like papules can be found in CLE as well. The present case highlights the rarity of presentation of CLE along Blaschko lines and overlapping features of Blaschko-linear CLE with DM.


Dermatology ◽  
2021 ◽  
pp. 1-10
Author(s):  
Astrid Herzum ◽  
Giulia Gasparini ◽  
Emanuele Cozzani ◽  
Martina Burlando ◽  
Aurora Parodi

Lupus erythematosus (LE) is an autoimmune disease with a wide range of clinical and cutaneous manifestations. Along with the well-known typical cutaneous manifestations of LE, some cutaneous manifestations are rarer, but still characteristic, enabling the dermatologist and the general practitioner who know them to suspect cutaneous LE (CLE) and investigate a possible underlying systemic involvement. Indeed, not infrequently a skin manifestation is the first presentation of systemic LE (SLE), and >75% of SLE patients show signs of skin disease during the course of the illness. Especially, SLE involvement occurs in cases of acute CLE, while it is uncommon in subacute CLE and rare in chronic CLE. This review aims to concentrate especially on atypical cutaneous manifestations of LE to enable the clinician to diagnose even the rarest forms of CLE.


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