α2-Macroglobulin Complexes with and Mediates the Endocytosis of β-Amyloid Peptide via Cell Surface Low-Density Lipoprotein Receptor-Related Protein

Β Amyloid ◽

Β Amyloid Peptide ◽

α2-Macroglobulin Enhances the Clearance of Endogenous Soluble β-Amyloid Peptide via Low-Density Lipoprotein Receptor-Related Protein in Cortical Neuron

Journal of Neurochemistry ◽

10.1046/j.1471-4159.1999.0731393.x ◽

2002 ◽

Vol 73 (4) ◽

pp. 1393-1398 ◽

Cited By ~ 89

Author(s):

Zhihua Qiu ◽

Dudley K. Strickland ◽

Bradley T. Hyman ◽

G. William Rebeck

Keyword(s):

Low Density Lipoprotein ◽

Density Lipoprotein ◽

Amyloid Peptide ◽

Lipoprotein Receptor ◽

Related Protein ◽

Α2 Macroglobulin ◽

Β Amyloid ◽

Β Amyloid Peptide ◽

Recognition of α2-Macroglobulin by the Low Density Lipoprotein Receptor-related Protein Requires the Cooperation of Two Ligand Binding Cluster Regions

Journal of Biological Chemistry ◽

10.1074/jbc.m104382200 ◽

2001 ◽

Vol 276 (42) ◽

pp. 39484-39491 ◽

Cited By ~ 51

Author(s):

Irina Mikhailenko ◽

Frances D. Battey ◽

Mary Migliorini ◽

Jose F. Ruiz ◽

Kelley Argraves ◽

...

Keyword(s):

Ligand Binding ◽

Low Density Lipoprotein ◽

Density Lipoprotein ◽

Low Density ◽

Lipoprotein Receptor ◽

Related Protein ◽

Α2 Macroglobulin ◽

Activated α2 macroglobulin induces matrix metalloproteinase 9 expression by low-density lipoprotein receptor-related protein 1 through MAPK-ERK1/2 and NF-κB activation in macrophage-derived cell lines

Journal of Cellular Biochemistry ◽

10.1002/jcb.22737 ◽

2010 ◽

Vol 111 (3) ◽

pp. 607-617 ◽

Cited By ~ 33

Author(s):

Leandro C. Cáceres ◽

Gustavo R. Bonacci ◽

María C. Sánchez ◽

Gustavo A. Chiabrando

Keyword(s):

Matrix Metalloproteinase ◽

Low Density Lipoprotein ◽

Density Lipoprotein ◽

Low Density ◽

Lipoprotein Receptor ◽

Related Protein ◽

Α2 Macroglobulin ◽

Metalloproteinase 9 ◽

Nickel Inhibits Binding of α2-Macroglobulin-Methylamine to the Low-Density Lipoprotein Receptor-Related Protein/α2-Macroglobulin Receptor but Not the α2-Macroglobulin Signaling Receptor†

Biochemistry ◽

10.1021/bi970806k ◽

1997 ◽

Vol 36 (41) ◽

pp. 12395-12399 ◽

Cited By ~ 19

Author(s):

Audrey R. Odom ◽

Uma K. Misra ◽

Salvatore V. Pizzo

Keyword(s):

Low Density Lipoprotein ◽

Density Lipoprotein ◽

Low Density ◽

Lipoprotein Receptor ◽

Related Protein ◽

Α2 Macroglobulin ◽

Increased soluble amyloid- peptide and memory deficits in amyloid model mice overexpressing the low-density lipoprotein receptor-related protein

Proceedings of the National Academy of Sciences ◽

10.1073/pnas.0305803101 ◽

2004 ◽

Vol 101 (4) ◽

pp. 1075-1080 ◽

Cited By ~ 85

Author(s):

C. V. Zerbinatti ◽

D. F. Wozniak ◽

J. Cirrito ◽

J. A. Cam ◽

H. Osaka ◽

...

Keyword(s):

Low Density Lipoprotein ◽

Density Lipoprotein ◽

Memory Deficits ◽

Amyloid Peptide ◽

Low Density ◽

Lipoprotein Receptor ◽

Related Protein ◽

Evidence that the newly cloned low-density-lipoprotein receptor related protein (LRP) is the α2 -macroglobulin receptor

FEBS Letters ◽

10.1016/0014-5793(90)80530-v ◽

1990 ◽

Vol 276 (1-2) ◽

pp. 151-155 ◽

Cited By ~ 214

Author(s):

Torsten Kristensen ◽

Søren K. Moestrup ◽

Jørgen Gliemann ◽

Lone Bendtsen ◽

Ole Sand ◽

...

Keyword(s):

Low Density Lipoprotein ◽

Density Lipoprotein ◽

Low Density ◽

Lipoprotein Receptor ◽

Related Protein ◽

Α2 Macroglobulin ◽

Three Complement-like Repeats Compose the Complete α2-Macroglobulin Binding Site in the Second Ligand Binding Cluster of the Low Density Lipoprotein Receptor-related Protein

Journal of Biological Chemistry ◽

10.1074/jbc.m604389200 ◽

2006 ◽

Vol 281 (45) ◽

pp. 34189-34196 ◽

Cited By ~ 19

Author(s):

Klavs Dolmer ◽

Peter G. W. Gettins

Keyword(s):

Ligand Binding ◽

Binding Site ◽

Low Density Lipoprotein ◽

Density Lipoprotein ◽

Low Density ◽

Lipoprotein Receptor ◽

Related Protein ◽

Α2 Macroglobulin ◽

Differential Binding Properties of Human Pregnancy Zone Protein– and α2-Macroglobulin–Proteinase Complexes to Low-Density Lipoprotein Receptor-Related Protein

Archives of Biochemistry and Biophysics ◽

10.1006/abbi.2001.2659 ◽

2002 ◽

Vol 398 (1) ◽

pp. 73-78 ◽

Cited By ~ 16

Author(s):

G.A. Chiabrando ◽

M.A. Vides ◽

M.C. Sánchez

Keyword(s):

Low Density Lipoprotein ◽

Density Lipoprotein ◽

Lipoprotein Receptor ◽

Related Protein ◽

Binding Properties ◽

Pregnancy Zone Protein ◽

Α2 Macroglobulin ◽

Differential Binding ◽

Role of the Low-density Lipoprotein Receptor–Related Protein in β-Amyloid Metabolism and Alzheimer Disease

Archives of Neurology ◽

10.1001/archneur.57.5.646 ◽

2000 ◽

Vol 57 (5) ◽

pp. 646 ◽

Cited By ~ 66

Author(s):

Bradley T. Hyman ◽

Dudley Strickland ◽

G. William Rebeck

Keyword(s):

Low Density Lipoprotein ◽

Density Lipoprotein ◽

Low Density ◽

Lipoprotein Receptor ◽

Related Protein ◽

Amyloid Metabolism ◽

Β Amyloid ◽

Expression of α2-macroglobulin receptor/low density lipoprotein receptor-related protein is increased in reactive and neoplastic glial cells

FEBS Letters ◽

10.1016/0014-5793(94)80288-2 ◽

1994 ◽

Vol 338 (3) ◽

pp. 301-305 ◽

Cited By ~ 51

Author(s):

M.Beatriz S. Lopes ◽

Christopher A. Bogaev ◽

Steven L. Gonias ◽

Scott R. VandenBerg

Keyword(s):

Glial Cells ◽

Low Density Lipoprotein ◽

Density Lipoprotein ◽

Low Density ◽

Lipoprotein Receptor ◽

Related Protein ◽

Α2 Macroglobulin ◽