Three Complement-like Repeats Compose the Complete α2-Macroglobulin Binding Site in the Second Ligand Binding Cluster of the Low Density Lipoprotein Receptor-related Protein

Klavs Dolmer; Peter G. W. Gettins

doi:10.1074/jbc.m604389200

Three Complement-like Repeats Compose the Complete α2-Macroglobulin Binding Site in the Second Ligand Binding Cluster of the Low Density Lipoprotein Receptor-related Protein

Journal of Biological Chemistry ◽

10.1074/jbc.m604389200 ◽

2006 ◽

Vol 281 (45) ◽

pp. 34189-34196 ◽

Cited By ~ 19

Author(s):

Klavs Dolmer ◽

Peter G. W. Gettins

Keyword(s):

Ligand Binding ◽

Binding Site ◽

Low Density Lipoprotein ◽

Density Lipoprotein ◽

Low Density ◽

Lipoprotein Receptor ◽

Related Protein ◽

Α2 Macroglobulin ◽

Density Lipoprotein Receptor ◽

Lipoprotein Receptor Related Protein

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Recognition of α2-Macroglobulin by the Low Density Lipoprotein Receptor-related Protein Requires the Cooperation of Two Ligand Binding Cluster Regions

Journal of Biological Chemistry ◽

10.1074/jbc.m104382200 ◽

2001 ◽

Vol 276 (42) ◽

pp. 39484-39491 ◽

Cited By ~ 51

Author(s):

Irina Mikhailenko ◽

Frances D. Battey ◽

Mary Migliorini ◽

Jose F. Ruiz ◽

Kelley Argraves ◽

...

Keyword(s):

Ligand Binding ◽

Low Density Lipoprotein ◽

Density Lipoprotein ◽

Low Density ◽

Lipoprotein Receptor ◽

Related Protein ◽

Low Density Lipoprotein Receptor ◽

Α2 Macroglobulin ◽

Density Lipoprotein Receptor ◽

Lipoprotein Receptor Related Protein

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Analysis of Ligand Binding to the α2-Macroglobulin Receptor/Low Density Lipoprotein Receptor-related Protein

Journal of Biological Chemistry ◽

10.1074/jbc.270.40.23713 ◽

1995 ◽

Vol 270 (40) ◽

pp. 23713-23719 ◽

Cited By ~ 19

Author(s):

Morten S. Nielsen ◽

Anders Nykjær ◽

Ilka Warshawsky ◽

Alan L. Schwartz ◽

Jørgen Gliemann

Keyword(s):

Ligand Binding ◽

Low Density Lipoprotein ◽

Density Lipoprotein ◽

Low Density ◽

Lipoprotein Receptor ◽

Related Protein ◽

Low Density Lipoprotein Receptor ◽

Α2 Macroglobulin ◽

Density Lipoprotein Receptor ◽

Lipoprotein Receptor Related Protein

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Activated α2 macroglobulin induces matrix metalloproteinase 9 expression by low-density lipoprotein receptor-related protein 1 through MAPK-ERK1/2 and NF-κB activation in macrophage-derived cell lines

Journal of Cellular Biochemistry ◽

10.1002/jcb.22737 ◽

2010 ◽

Vol 111 (3) ◽

pp. 607-617 ◽

Cited By ~ 33

Author(s):

Leandro C. Cáceres ◽

Gustavo R. Bonacci ◽

María C. Sánchez ◽

Gustavo A. Chiabrando

Keyword(s):

Matrix Metalloproteinase ◽

Low Density Lipoprotein ◽

Density Lipoprotein ◽

Low Density ◽

Lipoprotein Receptor ◽

Related Protein ◽

Α2 Macroglobulin ◽

Density Lipoprotein Receptor ◽

Metalloproteinase 9 ◽

Lipoprotein Receptor Related Protein

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The Second and Fourth Cluster of Class A Cysteine-rich Repeats of the Low Density Lipoprotein Receptor-related Protein Share Ligand-binding Properties

Journal of Biological Chemistry ◽

10.1074/jbc.274.44.31305 ◽

1999 ◽

Vol 274 (44) ◽

pp. 31305-31311 ◽

Cited By ~ 100

Author(s):

Jaap G. Neels ◽

Birgit M. M. van den Berg ◽

Aivar Lookene ◽

Gunilla Olivecrona ◽

Hans Pannekoek ◽

...

Keyword(s):

Ligand Binding ◽

Low Density Lipoprotein ◽

Density Lipoprotein ◽

Low Density ◽

Lipoprotein Receptor ◽

Related Protein ◽

Binding Properties ◽

Class A ◽

Density Lipoprotein Receptor ◽

Lipoprotein Receptor Related Protein

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Nickel Inhibits Binding of α2-Macroglobulin-Methylamine to the Low-Density Lipoprotein Receptor-Related Protein/α2-Macroglobulin Receptor but Not the α2-Macroglobulin Signaling Receptor†

Biochemistry ◽

10.1021/bi970806k ◽

1997 ◽

Vol 36 (41) ◽

pp. 12395-12399 ◽

Cited By ~ 19

Author(s):

Audrey R. Odom ◽

Uma K. Misra ◽

Salvatore V. Pizzo

Keyword(s):

Low Density Lipoprotein ◽

Density Lipoprotein ◽

Low Density ◽

Lipoprotein Receptor ◽

Related Protein ◽

Low Density Lipoprotein Receptor ◽

Α2 Macroglobulin ◽

Density Lipoprotein Receptor ◽

Lipoprotein Receptor Related Protein

Download Full-text

Sites within the 39-kDa protein important for regulating ligand binding to the low-density lipoprotein receptor-related protein

Biochemistry ◽

10.1021/bi00010a032 ◽

1995 ◽

Vol 34 (10) ◽

pp. 3404-3415 ◽

Cited By ~ 27

Author(s):

Ilka Warshawsky ◽

Guojun Bu ◽

Alan L. Schwartz

Keyword(s):

Ligand Binding ◽

Low Density Lipoprotein ◽

Density Lipoprotein ◽

Low Density ◽

Lipoprotein Receptor ◽

Related Protein ◽

Low Density Lipoprotein Receptor ◽

Density Lipoprotein Receptor ◽

Lipoprotein Receptor Related Protein

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Evidence that the newly cloned low-density-lipoprotein receptor related protein (LRP) is the α2 -macroglobulin receptor

FEBS Letters ◽

10.1016/0014-5793(90)80530-v ◽

1990 ◽

Vol 276 (1-2) ◽

pp. 151-155 ◽

Cited By ~ 214

Author(s):

Torsten Kristensen ◽

Søren K. Moestrup ◽

Jørgen Gliemann ◽

Lone Bendtsen ◽

Ole Sand ◽

...

Keyword(s):

Low Density Lipoprotein ◽

Density Lipoprotein ◽

Low Density ◽

Lipoprotein Receptor ◽

Related Protein ◽

Low Density Lipoprotein Receptor ◽

Α2 Macroglobulin ◽

Density Lipoprotein Receptor ◽

Lipoprotein Receptor Related Protein

Download Full-text

The Single Ligand-binding Repeat of Tva, a Low Density Lipoprotein Receptor-related Protein, Contains Two Ligand-binding Surfaces

Journal of Biological Chemistry ◽

10.1074/jbc.m512599200 ◽

2006 ◽

Vol 281 (32) ◽

pp. 22827-22838 ◽

Cited By ~ 2

Author(s):

Susana Contreras-Alcantara ◽

Jesse A. Godby ◽

Sue E. Delos

Keyword(s):

Ligand Binding ◽

Low Density Lipoprotein ◽

Density Lipoprotein ◽

Low Density ◽

Lipoprotein Receptor ◽

Related Protein ◽

Low Density Lipoprotein Receptor ◽

Density Lipoprotein Receptor ◽

Lipoprotein Receptor Related Protein

Download Full-text

Expression of α2-macroglobulin receptor/low density lipoprotein receptor-related protein is increased in reactive and neoplastic glial cells

FEBS Letters ◽

10.1016/0014-5793(94)80288-2 ◽

1994 ◽

Vol 338 (3) ◽

pp. 301-305 ◽

Cited By ~ 51

Author(s):

M.Beatriz S. Lopes ◽

Christopher A. Bogaev ◽

Steven L. Gonias ◽

Scott R. VandenBerg

Keyword(s):

Glial Cells ◽

Low Density Lipoprotein ◽

Density Lipoprotein ◽

Low Density ◽

Lipoprotein Receptor ◽

Related Protein ◽

Low Density Lipoprotein Receptor ◽

Α2 Macroglobulin ◽

Density Lipoprotein Receptor ◽

Lipoprotein Receptor Related Protein

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Expression of α2-macroglobulin receptor/low density lipoprotein receptor-related protein on surfaces of tumour ceils: a study using flow cytometry

Cancer Letters ◽

10.1016/s0304-3835(96)04520-x ◽

1997 ◽

Vol 111 (1-2) ◽

pp. 199-205 ◽

Cited By ~ 14

Author(s):

Yonghe Li ◽

Nick Wood ◽

Peter G. Parsons ◽

David Yellowlees ◽

Peter K. Donnelly

Keyword(s):

Flow Cytometry ◽

Low Density Lipoprotein ◽

Density Lipoprotein ◽

Low Density ◽

Lipoprotein Receptor ◽

Related Protein ◽

Low Density Lipoprotein Receptor ◽

Α2 Macroglobulin ◽

Density Lipoprotein Receptor ◽

Lipoprotein Receptor Related Protein

Download Full-text