Nail Matrix Arrest Following Hand‐Foot‐Mouth Disease: A Report of Five Children

2000 ◽  
Vol 17 (1) ◽  
pp. 7-11 ◽  
Author(s):  
Gina C. Clementz ◽  
Anthony J. Mancini
Viruses ◽  
2019 ◽  
Vol 11 (6) ◽  
pp. 522 ◽  
Author(s):  
Hsiu-Hui Chiu ◽  
Ming-Tsan Liu ◽  
Wen-Hung Chung ◽  
Yu-Shien Ko ◽  
Chin-Fang Lu ◽  
...  

Background: Nail changes, including onychomadesis (nail shedding) and Beau’s line, following hand-foot-mouth disease (HFMD) are a common emergence at the stage of late complications of HFMD. However, the exact mechanism is still unknown. Therefore, we conducted this study to elucidate the mechanism of nail changes following HFMD. Methods: We collected 11 patients suffering from onychomadesis following HFMD. Nail samples from all of them were collected. Real time reverse transcription polymerase chain reaction (RT-PCR) and sequencing for human enteroviruses (HEV) were performed. Throat swabs for RT-PCR and sequencing for HEV were performed for three cases. Results: RT-PCR demonstrated the presence of Coxackievirus A6 (CVA6) in nail samples from three patients and one with Echovirus. Conclusion: In conclusion, we believe that the major cause of onychomadesis following HFMD is that certain novel viruses, mostly CVA6, are virulent and may damage nail matrix. Direct injury caused by cutaneous lesions of HFMD around nail matrix is a minor cause. There are still other virulent HEV which may result in onychomadesis. In addition, the novel strain of CVA6 also causes atypical clinical presentations, such as adult involvement and delayed-onset palmar and plantar desquamation. Physicians should be familiar with atypical presentations caused by novel viruses to avoid misdiagnosis and even inform patients of the possibility of onychomadesis that may take place weeks later to reassure patients.


Author(s):  
Elisabetta Venturini ◽  
Luisa Galli ◽  
Elena Chiappini ◽  
Maurizio De Martino ◽  
Andrea Bassi

PLoS ONE ◽  
2014 ◽  
Vol 9 (3) ◽  
pp. e92745 ◽  
Author(s):  
Jiaojiao Wang ◽  
Zhidong Cao ◽  
Daniel Dajun Zeng ◽  
Quanyi Wang ◽  
Xiaoli Wang ◽  
...  

2021 ◽  
Vol 104 (8) ◽  
pp. 1229-1234

Background: Hand-foot-mouth disease (HFMD) is an infectious disease that mainly occurs in children under five years old. Vietnam is a developing country with high prevalence of the disease outbreak every year. Can Tho City, Co Do District had the highest incidence of children under five years old acquired HFMD. Objective: 1) To determine the factors correlating with knowledge, attitude, and practice in HFMD prevention of mothers having children under five years old, and 2) to evaluate the alteration in knowledge, attitude, and practice in prevention HFMD of mothers having children under five years old after intervention with health educational communication. Materials and Methods: Community intervention study was done in 420 subjects. At first, all the participants would do the questionnaire and practicing assessment. Then, the participants were divided into two groups, the intervened group for educational communication, and the control group with no intervention. The intervention included three steps, 1) training knowledge and skills for medical staffs and collaborators, 2) providing information about HFMD for the mothers, 3) broadcasting information leaflets to the subjects’ house every month. The assessment in awareness, attitude, and practice would be performed again after one month. The present study staff achieved approval from the Science and Educating Council of Can Tho University of Medicine and Pharmacy. In addition, the present study also received the agreement from The People’s Committee of Co Do District. Results: The present study results shows that 23.3% of mothers had the right knowledge, 50.5% of mothers had the right attitude, and 17.4% of mothers with children under five years of age had the right disease prevention practice. There was an association between education level of mothers with children under five years of age with knowledge, attitude, and practice in disease prevention. After intervention, knowledge of the mothers in the intervened group improved more than 2.79 times, right attitude more than 2.84 times, and practice improvement more than 1.83 times in compared with the control group. Conclusion: Educational communication plays an important role in HFMD disease prevention through increasing the awareness, opinion, and disease prevention of the mothers who directly take care of the under five years old children. Keywords: Hand-foot-mouth disease; Knowledge; Attitudes; Practices; Effective intervention


2012 ◽  
Vol 18 (8) ◽  
Author(s):  
Masami Toya ◽  
Yuichiro Endo ◽  
Hideaki Tanizaki ◽  
Akihiro Fujisawa ◽  
Miki Tanioka ◽  
...  

2010 ◽  
Vol 25 (5) ◽  
pp. 677 ◽  
Author(s):  
Sue K. Park ◽  
Boyoung Park ◽  
Moran Ki ◽  
Ho Kim ◽  
Kwan Lee ◽  
...  

2019 ◽  
Vol 23 (6) ◽  
Author(s):  
Chen Gao ◽  
Bichen Wu ◽  
Shaojie Yu ◽  
Fenghua Peng ◽  
Gongbin Lan ◽  
...  

2012 ◽  
Vol 11 (3) ◽  
pp. 381-385
Author(s):  
Guo Guangzhou ◽  
Zhang Dongxiao ◽  
Yang Fan ◽  
Wang Bing ◽  
Liu Tao ◽  
...  

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