scholarly journals Prospective, randomized study of atrioventricular node ablation and mode-switching, dual chamber pacemaker implantation using two different algorithms in patients with paroxysmal atrial fibrillation

EP Europace ◽  
1999 ◽  
Vol 1 (1) ◽  
pp. 20-21 ◽  
Author(s):  
H. J. Marshall ◽  
Z. I. Harris ◽  
M. J. Griffith ◽  
M. D. Gammage
EP Europace ◽  
1999 ◽  
Vol 1 (1) ◽  
pp. 15-19 ◽  
Author(s):  
M. Brignole ◽  
L. Gianfranchi ◽  
C. Menozzi ◽  
P. Alboni ◽  
G. Musso ◽  
...  

Abstract We performed a prospective randomized 6-month evaluation of the clinical effects of atrioventricular junctional ablation together with placement of a DDDR mode-switching pacemaker vs pharmacological treatment in 43 patients with intolerable paroxysmal atrial fibrillation not controlled with antiarrhythmic drugs. Ablation and pacemaker treatment were highly effective and superior to drug therapy in controlling symptoms and improving quality of life. However, discontinuation of drug therapy exposed patients to further recurrences of paroxysmal atrial fibrillation and the risk of developing permanent atrial fibrillation.


2005 ◽  
Vol 62 (4) ◽  
pp. 329-334
Author(s):  
Goran Radjen ◽  
Sasa Rafajlovski ◽  
Zoran Perisic ◽  
Radoslav Romanovic

Background. Atrial fibrillation is the most frequent cardiac dysrhythmia. The aim of this study was to show the role and the efficacy of a dual chamber pacemaker with the algorithm of atrial dynamic overdrive, in the suppression of paroxysmal atrial fibrillation. Case report. A woman with a classical bradycardia-tachycardia syndrome, and frequent attacks of atrial fibrillation, underwent the implantation of a single chamber permanent pacemaker (VVI). Pacemaker successfully treated the episodes of symptomatic bradycardia, but the patient had frequent attacks of atrial fibrillation, despite the use of different antiarrhythmic drugs, which she did not tolerate well. The decision was made to reimplant a permanent dual chamber pacemaker with the algorithm of atrial dynamic overdrive. The pacemaker was programmed to the basic rate of 75/min, while rate at rest was 55/min. In addition, sotalol was administered. After three months, the patient became asymptomatic with only 4 short ? term episodes of atrial fibrillation, and a high level of atrial pacing (99%). Conclusion. In selected patients with bradycardia?tachycardia syndrome, atrial-based pacing seemed to be very effective in reducing the incidence of paroxysmal atrial fibrillation.


EP Europace ◽  
1999 ◽  
Vol 1 (1) ◽  
pp. 8-13 ◽  
Author(s):  
M. Brignole ◽  
M. Gammage ◽  
L. Jordaens ◽  
R. Sutton

Abstract Atrioventricular junctional (AVJ) catheter ablation followed by pacemaker implantation is now widely accepted for patients affected by paroxysmal atrial fibrillation (PAF) not controlled by antiarrhythmic drugs. However, few data exist on its indications, optimal methodology and complications. Therefore a study group examined current practice in Europe and North America, using a questionnaire, followed by a Study Group Meeting to discuss the results. Based upon this, class I, class II and class III indications were proposed. Class I indications (for which general agreement existed) include drug-refractory PAF, correlating with important symptoms, the bradycardia–tachycardia syndrome already treated with a pacemaker, and continued PAF. Large differences exist in the current methodology, but consensus was reached on the technical approaches of right and left-sided AVJ ablation, and on the timing of pacemaker implant in relation to ablation. No complete agreement was reached on technical features such as catheter choice and heparin use. The recommended pacing mode was DDDR with mode switching.


2006 ◽  
Vol 17 (12) ◽  
pp. 1323-1328 ◽  
Author(s):  
JIM W. CHEUNG ◽  
RICHARD J. KEATING ◽  
KENNETH M. STEIN ◽  
STEVEN M. MARKOWITZ ◽  
SEI IWAI ◽  
...  

EP Europace ◽  
2001 ◽  
Vol 2 (Supplement_1) ◽  
pp. A71-A71
Author(s):  
A Nash ◽  
GJ Morgan-Hughes ◽  
AJ Marshall

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