79: Idiopathic Nodular Glomerulosclerosis in a Non-Diabetic Young Caucasian Male With Metabolic Syndrome: A Case Report

2010 ◽  
Vol 55 (4) ◽  
pp. B51
Author(s):  
Gurjit Dhatt ◽  
Bhagwan Dass ◽  
Stephen I-Hong Hsu
Keyword(s):  
Metabolic Syndrome ◽  
Case Report ◽  
Caucasian Male ◽  
Nodular Glomerulosclerosis ◽  
Idiopathic Nodular Glomerulosclerosis

scholarly journals Idiopathic nodular glomerulosclerosis in a chronic marijuana user; a case report and review of the literature

2017 ◽  
Vol 6 (4) ◽  
pp. 278-281 ◽  
Author(s):  
Mehri Mollaee ◽  
Tibor Fülöp ◽  
Sohil Abdul Salim ◽  
Mehrdad Hamrahian
Keyword(s):  
Case Report ◽  
Review Of The Literature ◽  
Marijuana User ◽  
Nodular Glomerulosclerosis ◽  
Idiopathic Nodular Glomerulosclerosis

Idiopathic Nodular Glomerulosclerosis: A Case Report

2012 ◽  
Vol 21 (01) ◽  
pp. 95-97
Author(s):  
Abdullah Sumnu ◽  
Meltem Gursu ◽  
Zeki Aydin ◽  
Sami Uzun ◽  
Serhat Karadag ◽  
...  
Keyword(s):  
Case Report ◽  
Nodular Glomerulosclerosis ◽  
Idiopathic Nodular Glomerulosclerosis

scholarly journals Erythromelanosis Follicularis Faciei et Colli: A Case Report in a Caucasian Male and Brief Review of the Literature

2020 ◽  
Vol 12 (3) ◽  
pp. 231-235
Author(s):  
Carl Maximilian Thielmann ◽  
Wiebke Sondermann
Keyword(s):  
Case Report ◽  
Family History ◽  
Clinical Presentation ◽  
Rare Condition ◽  
Unknown Etiology ◽  
Review Of The Literature ◽  
Caucasian Male

Erythromelanosis follicularis faciei et colli, a rare condition of unknown etiology, was first described by Kitamura et al. from Japan in 1960. It is characterized by a triad consisting of well-demarcated erythema, hyperpigmentation, and follicular papules. We report the case of a 50-year-old Caucasian male, who had asymptomatic symmetrical facial lesions since the age of 42. His family history was unremarkable. Published erythromelanosis follicularis faciei et colli cases of the last 10 years are summarized in this report to demonstrate the variability and differences in the clinical presentation of this uncommon diagnosis.

scholarly journals Equine metabolic syndrome in Colombian creole horse: case report

2017 ◽  
Vol 69 (5) ◽  
pp. 1067-1072
Author(s):  
C.A. Castillo ◽  
C. Jaramillo ◽  
M.J. Loaiza ◽  
R. Blanco
Keyword(s):  
Metabolic Syndrome ◽  
Case Report ◽  
Clinical Signs ◽  
South American ◽  
Adequate Treatment ◽  
Endocrine Organ ◽  
Equine Metabolic Syndrome ◽  
First Case ◽  
Combined Test ◽  
Lack Of Exercise

ABSTRACT The equine metabolic syndrome is a condition that can be recognized because of obesity, insulin resistance and laminitis. Genetic factors could play a role in the occurrence of this syndrome. Certain breeds such as ponies (including the South American creole horses) have a lower sensibility to insulin and a higher prevalence of hyperinsulinemia. The environment and management conditions, such as overfeeding and lack of exercise are factors that bring a propensity for obesity. The adipose tissue works as an endocrine organ producing hormones (adipokines or adipocytokines) that affect the horse´s metabolism. The objective of this report is to describe the first case report of a Colombian creole mare with a metabolic syndrome, diagnosed by means of the combined test of glucose-insulin and clinical signs. Early diagnosis of this entity and an adequate treatment are useful for improving the life and the zootechnical conditions of the patient.

scholarly journals Finding of pathological thrombomodulin gene variant in a patient with idiopathic nodular glomerulosclerosis and chronic thrombotic microangiopathy-like changes

2020 ◽  
Vol 8 ◽  
pp. 2050313X2094051
Author(s):  
Ramy Hanna ◽  
Jonathan E Zuckerman ◽  
Antoney Ferrey ◽  
Everado Arias Torres ◽  
Sam Tonthat ◽  
...  
Keyword(s):  
Alternative Pathway ◽  
Pathological Finding ◽  
Smoking History ◽  
Prior History ◽  
Diabetic Patients ◽  
Glomerular Injury ◽  
Nodular Glomerulosclerosis ◽  
Smoking Exposure ◽  
History Of ◽  
Idiopathic Nodular Glomerulosclerosis

Idiopathic nodular glomerulosclerosis is an unusual histopathological finding that has commonly been observed in male smokers with hypertension. It has remained an enigmatic condition and is best described as a diabetic pattern of glomerular injury seen in non-diabetic patients. It is also one of the few nicotine (smoking)-associated/smoking-associated patterns of renal injury. We present an even more unusual manifestation of this pathological finding in a 59-year-old Hispanic female who presented with chronic kidney disease approaching need for renal replacement therapy. The patient had idiopathic nodular glomerulosclerosis on kidney biopsy, despite no prior history of diabetes, nor smoking history, including no secondhand smoking exposure. The patient did have hypertension. The renal biopsy also showed evidence of chronic thrombotic-microangiopathic changes within arteries and arterioles. Genetic testing of the alternative pathway revealed an unusual and likely pathological variant of thrombomodulin supporting complement dysfunction as having a role in the presentation.

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