Chapter 27 discusses fracture fixation. Although many fractures are managed nonoperatively, others require various forms of surgical intervention. Fracture fixation can be conservative or surgical. The goal is to stabilize the fractured bone, enable fast healing, and return early mobility and function of the injured extremity. Orthopedic hardware permits stabilization of the fractured bone, expediting healing and early mobility. Percutaneous pins and wires can be used to apply traction to a fracture. External and internal fixation are used when more advanced operative intervention is required and encompass external fixator devices, pins/wires, screws, plates, and intramedullary nails/rods. Hardware is unfortunately susceptible to complication, including loosening, migration, fracture, and infection.