Hypertrophic Obstructive Cardiomyopathy Patient: Discrepancy between Hemodynamic Measurements in Cardiac Laboratory and Operating Room Is to Be Expected

Author(s):  
Juliano Lentz Carvalho ◽  
Elena Ashikhmina ◽  
Martin D. Abel ◽  
Jason K. Viehman ◽  
Brian D. Lahr ◽  
...  
2021 ◽  
pp. 021849232110471
Author(s):  
Jacobo Moreno Garijo ◽  
Cristina Ibáñez ◽  
Juan M Perdomo ◽  
Martin D Abel ◽  
Massimiliano Meineri

With an estimated overall mortality of less than 1 percent per year, hypertrophic cardiomyopathy, is the most common genetic cardiomyopathy. Intraoperative transesophageal echocardiography is the standard of care for assessing patients with hypertrophic obstructive cardiomyopathy undergoing surgical septal myectomy, allowing surgical planning, intraoperative hemodynamic monitoring, and postprocedural assessment of the repair, including detection of immediate complications. At various phases during surgical septal myectomy, the changing hemodynamic conditions may lead to worsening or improvement in left ventricle outflow tract obstruction by change in preload or afterload, systolic anterior motion of the mitral valve, or sympathetic stimulation. These characteristics represent unique challenges in the management of these patients, requiring a comprehensive understanding of the management of all the conditions required to decrease the left ventricle outflow tract gradient avoiding obstruction, which include the maintenance of sinus rhythm, adequate rate avoiding tachycardia and bradycardia, and avoidance of systemic hypotension preserving preload and afterload, with adequate vasoactive agents. The aim of this review is to summarize the perioperative assessment and management of patients undergoing hypertrophic obstructive myopathy surgery.


Author(s):  
Brandon M. Jones ◽  
Amar Krishnaswamy ◽  
Nicholas G. Smedira ◽  
Milind Y. Desai ◽  
E. Murat Tuzcu ◽  
...  

2013 ◽  
pp. 35-42
Author(s):  
Jusuf Endang ◽  
H Haryadi ◽  
Siska Suridanda ◽  
Andika S ◽  
Roy Christian ◽  
...  

Hypertrophic Obstructive Cardiomyopathy (HOCM) prevalence is about 1 among 500 population. It is caused by genetic malformation. Dyspnoe, angina pectoris and syncope are clinical manisfestation. Pharmacological and non-pharmacological treatments can be performed to relieve the obstructive symptoms. Recently alcohol septal ablation has been proven improve haemodynamic and functional status.We report a case of HOCM patient with refractory lung oedema and intubated due to respiratory failure that was immediatelly improved afterseptal ablation.


Author(s):  
J. D. Shelburne ◽  
Peter Ingram ◽  
Victor L. Roggli ◽  
Ann LeFurgey

At present most medical microprobe analysis is conducted on insoluble particulates such as asbestos fibers in lung tissue. Cryotechniques are not necessary for this type of specimen. Insoluble particulates can be processed conventionally. Nevertheless, it is important to emphasize that conventional processing is unacceptable for specimens in which electrolyte distributions in tissues are sought. It is necessary to flash-freeze in order to preserve the integrity of electrolyte distributions at the subcellular and cellular level. Ideally, biopsies should be flash-frozen in the operating room rather than being frozen several minutes later in a histology laboratory. Electrolytes will move during such a long delay. While flammable cryogens such as propane obviously cannot be used in an operating room, liquid nitrogen-cooled slam-freezing devices or guns may be permitted, and are the best way to achieve an artifact-free, accurate tissue sample which truly reflects the in vivo state. Unfortunately, the importance of cryofixation is often not understood. Investigators bring tissue samples fixed in glutaraldehyde to a microprobe laboratory with a request for microprobe analysis for electrolytes.


2007 ◽  
Vol 6 (1) ◽  
pp. 32-33
Author(s):  
L BOKERIA ◽  
A GUDKOVA ◽  
E SEMERNIN ◽  
A KRUTIKOV ◽  
E LOKHMATOVA ◽  
...  

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