Decreased heart rate recovery after exercise in patients with congestive heart failure: Effect of β-blocker therapy

2003 ◽  
Vol 9 (4) ◽  
pp. 296-302 ◽  
Author(s):  
Normand Racine ◽  
Martine Blanchet ◽  
Anique Ducharme ◽  
Johanne Marquis ◽  
Jean-Marc Boucher ◽  
...  
2017 ◽  
Vol 38 (3) ◽  
pp. 351-359 ◽  
Author(s):  
Wladimir M. Medeiros ◽  
Fabio A. de Luca ◽  
Alcides R. de Figueredo Júnior ◽  
Felipe A. R. Mendes ◽  
Carlos Gun

2009 ◽  
Vol 15 (3) ◽  
pp. 224-232 ◽  
Author(s):  
Yuji Nagatomo ◽  
Tsutomu Yoshikawa ◽  
Takashi Kohno ◽  
Akihiro Yoshizawa ◽  
Akiyasu Baba ◽  
...  

2004 ◽  
Vol 10 (4) ◽  
pp. 310-315 ◽  
Author(s):  
Akihiro Yoshizawa ◽  
Tsutomu Yoshikawa ◽  
Iwao Nakamura ◽  
Toru Satoh ◽  
Kazunori Moritani ◽  
...  

2006 ◽  
Vol 25 (8) ◽  
pp. 942-945 ◽  
Author(s):  
David S. Hirsh ◽  
Timothy J. Vittorio ◽  
Svetlana L. Barbarash ◽  
Alhakam Hudaihed ◽  
Chi-Hong Tseng ◽  
...  

1996 ◽  
Vol 131 (2) ◽  
pp. 329-336 ◽  
Author(s):  
Tsutomu Yoshikawa ◽  
Shunnosuke Handa ◽  
Toshihisa Anzai ◽  
Hiroshi Nishimura ◽  
Akiyasu Baba ◽  
...  

2015 ◽  
Vol 26 (7) ◽  
pp. 1274-1281 ◽  
Author(s):  
Paulo Peres ◽  
Antônio C. Carvalho ◽  
Ana Beatriz A. Perez ◽  
Wladimir M. Medeiros

AbstractBackgroundMarfan syndrome patients present important cardiac structural changes, ventricular dysfunction, and electrocardiographic changes. An abnormal heart rate response during or after exercise is an independent predictor of mortality and autonomic dysfunction. The aim of the present study was to compare heart rate recovery and chronotropic response obtained by cardiac reserve in patients with Marfan syndrome subjected to submaximal exercise.MethodsA total of 12 patients on β-blocker therapy and 13 off β-blocker therapy were compared with 12 healthy controls. They were subjected to submaximal exercise with lactate measurements. The heart rate recovery was obtained in the first minute of recovery and corrected for cardiac reserve and peak lactate concentration.ResultsPeak heart rate (141±16 versus 155±17 versus 174±8 bpm; p=0.001), heart rate reserve (58.7±9.4 versus 67.6±14.3 versus 82.6±4.8 bpm; p=0.001), heart rate recovery (22±6 versus 22±8 versus 34±9 bpm; p=0.001), and heart rate recovery/lactate (3±1 versus 3±1 versus 5±1 bpm/mmol/L; p=0.003) were different between Marfan groups and controls, respectively. All the patients with Marfan syndrome had heart rate recovery values below the mean observed in the control group. The absolute values of heart rate recovery were strongly correlated with the heart rate reserve (r=0.76; p=0.001).ConclusionMarfan syndrome patients have reduced heart rate recovery and chronotropic deficit after submaximal exercise, and the chronotropic deficit is a strong determinant of heart rate recovery. These changes are suggestive of autonomic dysfunction.


2007 ◽  
Vol 23 (14) ◽  
pp. 1135-1138 ◽  
Author(s):  
Richard Sheppard ◽  
Normand Racine ◽  
Andre Roof ◽  
Anique Ducharme ◽  
Martine Blanchet ◽  
...  

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