The central role of magnesium deficiency in Tourette's syndrome: causal relationships between magnesium deficiency, altered biochemical pathways and symptoms relating to Tourette's syndrome and several reported comorbid conditions

Background. The treatment of Tourette's syndrome (TS) is often unsatisfactory. However, there is some evidence that transdermal nicotine patch (TNP) application may improve tics of non-smoking TS patients who are refractory to haloperidol treatment.Methods. In this open study we applied two 10 mg TNP for 2 consecutive days to four TS patients whose symptoms were not controlled by haloperidol and to a never-medicated TS patient, all of whom are non-smokers. The Yale Global Tic Severity Scale (YGTSS) and a quantified video-taped micro-structured analysis of tics (head-shake tics, eye-blinks, vocal tics, facial grimace and other body tics) were both carried out to assess the change after the application of TNP.Results. TNP application significantly reduced the YGTSS by an average of 50%, with no reported side-effects, for up to 4 weeks but not 16 weeks, as compared with TNP-free period. Consistent with these results, the total counts of tics also showed a significant decrease for up to 4 weeks after the TNP application.Conclusion. TNP application differentially affected individually quantified tics, which may suggest a differential role of nicotinic receptors in the generation of different tics.

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The role of mutations on gene SLITRK1, in Tourette’s Syndrome

The Gazette of Medical Sciences ◽

10.46766/thegms.medgen.20100501 ◽

2020 ◽

Vol 1 (5) ◽

pp. 47-51

Author(s):

Shahin Asadi ◽

Keyword(s):

Tourette's Syndrome ◽

Tourette’S Syndrome

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Peran Penerimaan Sosial terhadap Psikopatologi Perkembangan Sindrom Tourette Pada Anak

BUANA GENDER Jurnal Studi Gender dan Anak ◽

10.22515/bg.v1i2.234 ◽

2016 ◽

Vol 1 (2) ◽

pp. 129

Author(s):

Ellen Prima

Keyword(s):

Developmental Psychopathology ◽

Social Acceptance ◽

Tourette's Syndrome ◽

Tourette’S Syndrome ◽

Full Potential ◽

Body Parts ◽

The Social ◽

The Face ◽

Pressure Stress

One of the developmental psychopathology types that often occur in childhood is Tourette's syndrome which begins with mild symptoms such as mild tic movements on the face, head or hands. Tic will often arise when the children feel under pressure (stress) and their emotion is unstable. It increases simultaneously with ones age including legs and other body parts. Tourette's syndrome may infect every one of all ethnic groups. The aim of this study was to identify and describe the role of social acceptance towards the developmental psychopathology of Tourette's syndrome in children. Therefore, this study uses a descriptive qualitative method. The results of this study indicate that the social acceptance (environment) helps a person to adapt well and be able to use his full potential, especially for the person suffering from developmental psychopathology of Tourettes syndrome.Salah satu jenis psikopatologi perkembangan yang sering terjadi pada masa kanak-kanak yaitu sindrom tourette yang diawali dengan gejala ringan seperti gerakan tik ringan pada wajah, kepala atau tangan. Tik sering muncul jika anak merasa tertekan (stres) dan adanya ketidakstabilan emosi. Hal itu semakin meningkat seiring dengan bertambahnya usia seseorang yang mencakup beberapa bagian tubuh lain seperti kaki dan anggota tubuh yang lain. Sindrom tourette dapat terjadi pada setiap orang dari semua kelompok etnis. Tujuan dari penelitian ini adalah untuk mengetahui dan menjelaskan peran penerimaan sosial terhadap psikopatologi perkembangan sindrom Tourette pada anak. Oleh karena itu, penelitian ini menggunakan metode kualitatif jenis deskriptif. Hasil dari penelitian ini menunjukkan bahwa penerimaan secara sosial (lingkungan) sangat membantu seseorang dalam beradaptasi dengan baik dan dapat menggunakan potensinya secara maksimal terutama bagi orang yang mengalami penyimpangan perkembangan salah satunya adalah sindrom tourette.

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Faculty Opinions recommendation of Tourette's syndrome and role of tetrabenazine: review and personal experience.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.726088496.793513710 ◽

2016 ◽

Author(s):

Joseph Jankovic ◽

Mary Ann Thenganatt

Keyword(s):

Personal Experience ◽

Tourette's Syndrome ◽

Tourette’S Syndrome

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The Role of the Amygdaloid Complex in Gilles de la Tourette's Syndrome

The British Journal of Psychiatry ◽

10.1192/bjp.161.4.532 ◽

1992 ◽

Vol 161 (4) ◽

pp. 532-534 ◽

Cited By ~ 6

Author(s):

Danitza Jadresic

Keyword(s):

Attention Deficit Disorder ◽

Amygdaloid Complex ◽

Tourette's Syndrome ◽

Medical Attention ◽

Tourette’S Syndrome ◽

Compulsive Disorder ◽

Self Injury ◽

Family Pedigree ◽

Motor Tics

Gilles de la Tourette's syndrome (GTS) is a relatively rare neuropsychiatric disorder characterised by multiple motor tics accompanied by vocalisations. It usually starts in early childhood and is more common in males than females. Obsessional compulsive disorder (OCD) is an integral part of GTS (Robertson, 1989). GTS is also associated with coprolalia, copropraxia, and other echophenomena, as well as attention-deficit disorder, self-injury, and other behaviour problems (Robertson et al, 1988; Robertson, 1989). Family pedigree studies have demonstrated that most GTS cases in the community are mild and do not receive medical attention (Kurlan et al, 1987; Robertson & Gourdie, 1990).

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