Towards Rare-Functionalized N-Alkenyl-1H-pyrroles via Regioselectively Metalated N-Isopropenyl-1H-pyrroles

Synthesis ◽  
2022 ◽  
Author(s):  
Boris Trofimov ◽  
Olga Tarasova ◽  
Marina Maximova ◽  
Alexander Albanov ◽  
Nina Nedolya
Keyword(s):  
Regioselective Functionalization

Deprotonative metalation of N-isopropenyl-1H-pyrroles with superbases followed by trapping with a variety of electrophiles was studied as an effective tool for the regioselective functionalization of 1H-pyrroles

The Regioselective Functionalization of Pyridine at 2,3,4-positions via Carbene Intermediate

2018 ◽  
Vol 22 (15) ◽  
pp. 1536-1553 ◽  
Author(s):  
Aamer Saeed ◽  
Muhammad Zain-ul-Abideen ◽  
Muhammad N. Mustafa
Keyword(s):  
Regioselective Functionalization

Regioselective Functionalization of N-Fused Heteroaromatics via FeCl3-Catalyzed Nucleophilic Addition to Activated N-Heterocycles

Synthesis ◽  
2020 ◽  
Author(s):  
Ikyon Kim ◽  
Sung June Kim ◽  
Sunhee Lee
Keyword(s):  
Aromatic Compounds ◽  
Nucleophilic Addition ◽  
Chemical Space ◽  
Wide Range ◽  
Regioselective Functionalization

AbstractBroadening of nitrogen-fused heteroaromatic chemical space such as indolizine and pyrrolo[1,2-a]pyrazine was achieved via FeCl­3-catalyzed nucleophilic addition of these N-fused aromatic compounds to a wide range of azolinium systems generated in situ, leading to novel N-fused heteroaromatic scaffolds with dearomatized N-heterocyclic substituents regioselectively. Nucleophilic addition of indolizines and pyrrolo[1,2-a]pyrazines mainly occurred at the C1 position of the isoquinoliniums and at the C4 site of the quinoliniums.

scholarly journals Directed Regioselective ortho,ortho’-Magnesiations of Aromatics and Heterocycles using sBu2Mg in Toluene

2021 ◽  
Author(s):  
Andreas Hess ◽  
Jan Philip Prohaska ◽  
Sabrina Bettina Doerrich ◽  
Florian Trauner ◽  
Ferdinand Hermann Lutter ◽  
...  
Keyword(s):  
Bioactive Compounds ◽  
Regioselective Functionalization

Aryl azoles are ubiquitous as bioactive compounds and their regioselective functionalization is of utmost synthetic importance. Here, we report the development of a toluene-soluble dialkylmagnesium base sBu2Mg. This new reagent...

ChemInform Abstract: Regioselective Functionalization of Bis(trimethylsilyl)methylimines with Electrophiles.

ChemInform ◽  
2010 ◽  
Vol 26 (9) ◽  
pp. no-no
Author(s):  
A. RICCI ◽  
A. GUERRINI ◽  
G. SECONI ◽  
A. MORDINI ◽  
T. CONSTANTIEUX ◽  
...  
Keyword(s):  
Regioselective Functionalization

scholarly journals Smart Hydrophobic-Hydrophilic Self-Switching Cellulosic Materials Synthesized by Regioselective Functionalization

BioResources ◽  
2018 ◽  
Vol 13 (1) ◽  
Author(s):  
Meiyan Lin ◽  
Kunfeng Xia ◽  
Pengbo Lu ◽  
Yanghao Ou ◽  
Lingfeng Su ◽  
...  
Keyword(s):  
Cellulosic Materials ◽  
Regioselective Functionalization

Pd-Catalyzed thiophene directed regioselective functionalization of arenes: a direct approach to multiply-substituted benzyl amines

2017 ◽  
Vol 4 (8) ◽  
pp. 1503-1507 ◽  
Author(s):  
Jundie Hu ◽  
Guobao Li ◽  
Zhi-Bin Huang ◽  
Jingyu Zhang ◽  
Da-Qing Shi ◽  
...  
Keyword(s):  
Palladium Catalyst ◽  
Direct Approach ◽  
Regioselective Functionalization

A thiophene directed ortho-C–H functionalization via a palladium catalyst in the synthesis of multiply-substituted benzyl amines has been developed.

REGIOSELECTIVE FUNCTIONALIZATION OF cis-BICYCLO|3.3.0|OCTENONE DERIVATIVES. OXYMERCURATION/REDUCTION versus HYDROBORATION/OXIDATION. ACETAL GROUPS AS REGIO- AND STEREOSELECTIVE CONTROL ELEMENTS

1984 ◽  
Vol 13 (5) ◽  
pp. 775-778 ◽  
Author(s):  
Elena Carceller ◽  
Assumpta Castelló ◽  
M. Lluísa García ◽  
Albert Moyano ◽  
Félix Serratosa
Keyword(s):  
Regioselective Functionalization
Sign in / Sign up

Export Citation Format

Share Document