▪ Cryosurgery and Thermal Ablation of Primary Liver Tumors and Hepatic Metastases

2007 ◽  
Keyword(s):  
Thermal Ablation ◽  
Liver Tumors ◽  
Hepatic Metastases ◽  
Primary Liver Tumors

Recognizing and Managing Adverse Events in Y-90 Radioembolization

2021 ◽  
Vol 38 (04) ◽  
pp. 453-459
Author(s):  
Grace L. Laidlaw ◽  
Guy E. Johnson
Keyword(s):  
Adverse Events ◽  
Patient Care ◽  
Liver Tumors ◽  
Hepatic Metastases ◽  
Systemic Effects ◽  
Primary Liver Tumors ◽  
Transarterial Radioembolization ◽  
Prevention And Treatment ◽  
Yttrium 90

AbstractTransarterial radioembolization using yttrium-90 (Y-90) microspheres is an important therapy in the management of unresectable primary liver tumors or hepatic metastases. While radioembolization is generally well-tolerated, it is not free from adverse events, and familiarity with the prevention and treatment of radioembolization-specific complications is an important component of patient care. This article aims to review radioembolization-specific toxicities stratified by hepatic, extrahepatic, and systemic effects, with a focus on preventing and mitigating radioembolization-induced morbidity.

scholarly journals Locoregional Therapies for the Treatment of Uveal Melanoma Hepatic Metastases

2020 ◽  
Vol 37 (05) ◽  
pp. 508-517
Author(s):  
Carin F. Gonsalves ◽  
Robert D. Adamo ◽  
David J. Eschelman
Keyword(s):  
Uveal Melanoma ◽  
Thermal Ablation ◽  
Systemic Treatment ◽  
Liver Tumors ◽  
Treatment Options ◽  
Hepatic Metastases ◽  
Hepatic Tumors ◽  
Imaging Surveillance ◽  
Locoregional Therapies ◽  
Percutaneous Hepatic Perfusion

AbstractUveal melanoma is the most common primary intraocular malignant tumor in adults. Approximately 50% of patients develop metastatic disease of which greater than 90% of patients develop hepatic metastases. Following the development of liver tumors, overall survival is dismal with hepatic failure being the cause of death in nearly all cases. To prolong survival for patients with metastatic uveal melanoma, controlling the growth of hepatic tumors is essential. This article will discuss imaging surveillance following the diagnosis of primary uveal melanoma; locoregional therapies used to control the growth of hepatic metastases including chemoembolization, immunoembolization, radioembolization, percutaneous hepatic perfusion, and thermal ablation; as well as currently available systemic treatment options for metastatic uveal melanoma.

Ablation in Primary Liver Tumors

2019 ◽  
Vol 03 (02) ◽  
pp. 107-116
Author(s):  
D. Putzer ◽  
P. Schullian ◽  
R. Bale
Keyword(s):  
Thermal Ablation ◽  
Liver Tumors ◽  
Large Diameter ◽  
Three Dimensional ◽  
Safety Margin ◽  
Minimal Invasive ◽  
R0 Resection ◽  
Recurrence Rates ◽  
Stereotactic Techniques ◽  
Primary Liver Tumors

Minimal invasive thermal ablation techniques have a key role in the treatment regimen of primary liver tumors. These relatively low-risk procedures are established in nonresectable liver tumors and even challenge the surgical approach, which is regarded as first-line treatment in eligible patients.The location and size of the liver tumor, the applied ablation, and guidance technique are crucial for treatment outcome. The confirmation of an adequate ablation zone including sufficient tumor overlap and a safety margin (A0 ablation analogous to R0 resection) is crucial to minimize local recurrence rates and improve survival. A variety of different ablation devices is available. The outcome of conventional computed tomography- or ultrasound-guided thermal ablation in small lesions is well comparable to surgery. However, in liver lesions with large diameter overlapping ablation zones are required to ensure an adequate ablation margin. Therefore, stereotactic techniques in combination with a multiple needle approach, three-dimensional trajectory planning, and image fusion for intraoperative treatment evaluation have been successfully introduced.

Radiofrequency Thermal Ablation of Metastatic Liver Tumors: Usefulness of Combined Chemotherapy

2001 ◽  
Vol 45 (2) ◽  
pp. 147
Author(s):  
Jeong Nam Heo ◽  
Hyun Chul Rhim ◽  
Yong Soo Kim ◽  
Byung Hee Koh ◽  
On Koo Cho ◽  
...  
Keyword(s):  
Thermal Ablation ◽  
Liver Tumors ◽  
Combined Chemotherapy ◽  
Radiofrequency Thermal Ablation ◽  
Metastatic Liver Tumors ◽  
Metastatic Liver

Eight years after introducing liver resection at the Oncology Institute of Vojvodina

2013 ◽  
Vol 21 (3-4) ◽  
pp. 101-104
Author(s):  
Ivan Majdevac ◽  
Nikola Budisin ◽  
Milan Ranisavljevic ◽  
Dejan Lukic ◽  
Imre Lovas ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Liver Resection ◽  
Liver Tumors ◽  
Liver Parenchyma ◽  
Malignant Neoplasms ◽  
Chemotherapy Treatment ◽  
Primary Liver Tumors ◽  
Cancer Metastases ◽  
Colorectal Cancer Metastases ◽  
Medical Histories

Background: Hepatectomies are mostly performed for the treatment of hepatic benign or malignant neoplasms, intrahepatic gallstones, or parasitic cysts of the liver. The most common malignant neoplasms of the liver are metastases from colorectal cancer. Anatomic liver resection involves two or more hepatic segments, while non-anatomic liver resection involves resection of the metastases with a margin of uninvolved tissue. The aim of this manuscript was to show results of hepatectomies performed at the Oncology Institute of Vojvodina. Methods: We performed 133 liver resections from January 1997 to December 2013. Clinical and histopathological data were obtained from operative protocols, histopathological reports, and patients? medical histories. Results: We did 80 metastasectomies, 51 segmentectomies, and 18 radiofrequent ablations (RFA). Average number of colorectal cancer metastases was 1.67 per patient. We also made 10 left hepatectomies. In all cases, we made non-anatomic resections. Conclusion: Decision about anatomic versus non-anatomic resections for colorectal metastasis and primary liver tumors should be made before surgical exploration. Preservation of liver parenchyma is important with respect to liver failure and postoperative chemotherapy treatment.

Rearrangement of a common cellular DNA domain on chromosome 4 in human primary liver tumors.

1988 ◽  
Vol 62 (2) ◽  
pp. 629-632 ◽  
Author(s):  
C Pasquinelli ◽  
F Garreau ◽  
L Bougueleret ◽  
E Cariani ◽  
K H Grzeschik ◽  
...  
Keyword(s):  
Liver Tumors ◽  
Chromosome 4 ◽  
Primary Liver Tumors ◽  
Cellular Dna

Fiber-Optic EFPI/FBG Dual Sensor for Monitoring of Radiofrequency Thermal Ablation of Liver Tumors

CLEO: 2014 ◽  
2014 ◽  
Author(s):  
D. Tosi ◽  
E. G. Macchi ◽  
M. Gallati ◽  
G. Braschi ◽  
A. Cigada ◽  
...  
Keyword(s):  
Thermal Ablation ◽  
Fiber Optic ◽  
Liver Tumors ◽  
Radiofrequency Thermal Ablation ◽  
Dual Sensor

Orthotopic liver transplantation in primary liver tumors

1993 ◽  
Vol 53 (S3) ◽  
pp. 74-77 ◽  
Author(s):  
Enrique Moreno-González ◽  
Carmelo Loinaz ◽  
Ramon Gómez ◽  
Ignacio Garclá ◽  
Ignacio González-Pinto ◽  
...  
Keyword(s):  
Liver Transplantation ◽  
Orthotopic Liver Transplantation ◽  
Liver Tumors ◽  
Primary Liver Tumors

scholarly journals Profile of hepatocellular carcinoma in the Republic of Moldova: first-hand information on the presentation, distribution and etiologies

2019 ◽  
Vol 57 (1) ◽  
pp. 37-46
Author(s):  
Adela Turcanu ◽  
Ecaterina Pitel ◽  
Vlada-Tatiana Dumbrava ◽  
Eugen Tcaciuc ◽  
Ana Donscaia ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Liver Tumors ◽  
Hepatitis Virus ◽  
Primary Liver Cancer ◽  
Virus Surface ◽  
Primary Liver Tumors ◽  
B Virus ◽  
Tertiary Healthcare ◽  
Serum Alpha Fetoprotein ◽  
The Republic

Abstract Introduction. Moldova is the European country with the highest incidence of hepatocellular carcinoma (HCC) in both sexes. There is, however, no data comprehensively describing the presentation and the risk factors of HCC in the country. We decided to analyze cases of HCC recently received in a tertiary healthcare Institution from Chisinau, the Moldovian capital. Methods. A series of 148 primary liver tumors including 139 cases of HCC were retrospectively analyzed for demographic features, serological and biochemical data, and clinical presentation. Results. The mean age of patients was 59 ± 10 years (range: 19-66) with a M:F sex ratio of 1.9. Tumors appeared on full-blown liver cirrhosis in 83% of cases and were composed of multiple nodules at diagnosis in 36% of patients. Serum Alpha-fetoprotein was exceeding 10ng/mL in 76% of cases. Liver tumor and hepatitis were co-discovered in 34% of cases. More than 81% of hepatocellular carcinomas were associated with at least one hepatitis virus. Carriers of anti-hepatitis C virus were predominating (55% of cases) over patients seropositive for hepatitis B virus surface antigen (36%). Half of the latter were also infected with hepatitis Delta virus. In total, dual or triple infections were present in 24% and 7% of cases. Conclusions. The burden of infections with hepatitis viruses is particularly important in Moldova and corresponds to a situation commonly observed in countries of the Southern hemisphere. A pro-active policy of screening for persistent liver infection targeting population at risk of HCC (> 50 years) and coupled with the distribution of antivirals in positive cases should be rapidly implemented in Moldova to reduce incidence or primary liver cancer.

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