Researches regarding skin anti-photoaging effect of Linum usitatissimum L. oil by using an in vivo skin imagistic dermatologic evaluation

Planta Medica ◽  
2011 ◽  
Vol 77 (12) ◽  
Author(s):  
G Pop ◽  
A Laza ◽  
A Dragomirescu ◽  
I Radulov ◽  
D Pop
Nutrients ◽  
2021 ◽  
Vol 13 (8) ◽  
pp. 2759
Author(s):  
Hamza Mechchate ◽  
Imane Es-safi ◽  
Raffaele Conte ◽  
Christophe Hano ◽  
Amal Amaghnouje ◽  
...  

Flaxseed is an oilseed (45–50% oil on a dry-weight basis) crop. Its oil has demonstrated multiple health benefits and industrial applications. The goal of this research was to evaluate the antidiabetic and anti-inflammatory potential of the free polyphenol fraction of flax (Linum usitatissimum L.) seeds (PLU), based on their use in traditional medicine. Mice with alloxan-induced diabetes were used to study the antidiabetic activity of PLU in vivo, with an oral administration of 25 and 50 mg/kg over 28 days. Measurements of body weight and fasting blood glucose (FBG) were carried out weekly, and biochemical parameters were evaluated. An oral glucose tolerance test was also performed. Inhibitory activities of PLU on α-amylase and α-glucosidase activities were evaluated in vitro. The anti-inflammatory was evaluated in vivo in Wistar rats using the paw edema induction Test by carrageenan, and in vitro using the hemolysis ratio test. PLU administration to diabetic mice during the study period improved their body weight and FBG levels remarkably. In vitro inhibitory activity of digestive enzymes indicated that they may be involved in the proposed mode of action of PLU extract. Qualitative results of PLU revealed the presence of 18 polyphenols. These findings support daily consumption of flaxseed for people with diabetes, and suggest that polyphenols in flaxseed may serve as dietary supplements or novel phytomedicines to treat diabetes and its complications.


2011 ◽  
Vol 47 (4) ◽  
pp. 817-823 ◽  
Author(s):  
Shyamoshree Basu ◽  
Amal Kumar Bandyopadhyay

Nasal drug delivery systems prepared from natural materials are gaining importance in the field of pharmaceutical technology. Mucilage isolated from Linum usitatissimum L. (LUM) seeds was reported to be an effective natural mucoadhesive agent. The present study deals with a comparison of various characteristics of nasal gels containing midazolam hydrochloride (HCl) prepared from mucoadhesive agent extracted from Linum usitatissimum L. seeds and synthetic polymers like HPMC and Carbopol 934P in terms of texture profile analysis, mucoadhesive strength, and in vivo drug absorption profiles. It was observed that gels formulated with the natural mucilage showed better results than the synthetic gels in all aspects like hardness, adhesiveness, cohesiveness and mucoadhesive strength. The absolute bioavailability of midazolam hydrochloride from the natural gel was 97.55% whereas that of synthetic gels was 57.33% and 76.81% respectively.


Planta Medica ◽  
2016 ◽  
Vol 81 (S 01) ◽  
pp. S1-S381
Author(s):  
H El-Askary ◽  
S El Zalabani ◽  
RS El-Din ◽  
MY Issa ◽  
RR Hegazy ◽  
...  

2016 ◽  
Vol 51 (5) ◽  
pp. 602-616 ◽  
Author(s):  
И.В. УЩАПОВСКИЙ И.В. УЩАПОВСКИЙ ◽  
◽  
В.А. ЛЕМЕШ В.А. ЛЕМЕШ ◽  
М.В. БОГДАНОВА М.В. БОГДАНОВА ◽  
Е.В. ГУЗЕНКО Е.В. ГУЗЕНКО ◽  
...  

2011 ◽  
Vol 59 (1) ◽  
pp. 87-102 ◽  
Author(s):  
S. Sood ◽  
N. Kalia ◽  
S. Bhateria

Combining ability and heterosis were calculated for fourteen lines of linseed in a line × tester mating design using twelve lines and two diverse testers in two different environments. The hybrids and parental lines were raised in a completely randomized block design with three replications to investigate seed and fibre yield and their component traits. Genetic variation was significant for most of the traits over environments. Combining ability studies revealed that the lines KL-221 and LCK-9826 were good general combiners for seed yield and most of its components, whereas LMH-62 and LC-2323 were good general combiners for yield components only. Moreover, KL-221 was also a good general combiner for fibre yield. Similarly, B-509 and Ariane were good general combiners for fibre yield and most of its components. Among the specific cross combinations, B-509 × Flak-1 was outstanding for seed yield per plant and B-509 × KL-187 and LC-2323 × LCK-9826 for fibre yield per plant, with high SCA effects. In general, the hybrids excelled their respective parents and the standard checks for most of the characters studied. Based on the comparison of mean performance, SCA effects and the extent of heterosis, the hybrids LC-2323 × LCK-9826 and B-509 × KL-221 appeared to be the most promising for both seed and fibre yield. Other promising combinations were LC-2323 × KL-210 and B-509 × Ariane for seed and fibre yield, respectively. The superiority of LC-2323, LCK-9826, KL-221, B-509 and Ariane as good general combiners was further confirmed by the involvement of these parents in the desirable cross combinations.


2015 ◽  
Vol 176 (4) ◽  
pp. 436-455
Author(s):  
S. N. Kutuzova ◽  
◽  
E. A. Porokhovinova ◽  
G. I. Pendinen ◽  
◽  
...  

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