Screening of Venezuelan medicinal plant extracts for cytostatic and cytotoxic activity against tumour cell lines

Planta Medica ◽  
2012 ◽  
Vol 78 (11) ◽  
Author(s):  
P Taylor ◽  
M Arsenak ◽  
MJ Abad ◽  
Á Fernández ◽  
R Gonto ◽  
...  
2012 ◽  
Vol 27 (4) ◽  
pp. 530-539 ◽  
Author(s):  
Peter Taylor ◽  
Miriam Arsenak ◽  
María Jesús Abad ◽  
Ángel Fernández ◽  
Balentina Milano ◽  
...  

Planta Medica ◽  
2013 ◽  
Vol 79 (13) ◽  
Author(s):  
O Estrada ◽  
L González ◽  
M Mijares ◽  
Á Fernández ◽  
M Ruiz ◽  
...  

2016 ◽  
Vol 182 ◽  
pp. 10-15 ◽  
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Joseph M. Nguta ◽  
Regina Appiah-Opong ◽  
Alexander K. Nyarko ◽  
Dorothy Yeboah-Manu ◽  
Phyllis G.A. Addo ◽  
...  

2009 ◽  
Vol 64 (3-4) ◽  
pp. 179-185 ◽  
Author(s):  
Nicolay I. Dodoff ◽  
Iordan Iordanov ◽  
Iana Tsoneva ◽  
Konstantin Grancharov ◽  
Roumyana Detcheva ◽  
...  

The series of complexes: cis-[Pd(PMSA)2X2], cis-[Pt(PMSA)2X2], trans-[Pt(PMSA)2I2] and [Pt(PMSA)4]Cl2 (PMSA = N-3-pyridinylmethanesulfonamide; X = Cl, Br, I), previously synthesized and characterized by us, as well as the free ligand PMSA, were tested for their cytotoxic activity without electroporation - against murine leukemia F4N and human SKW-3 and MDA-MB-231 tumour cell lines - and with electroporation - against the latter two cell lines. The majority of the complexes exhibited cytotoxic effects (IC50 < 100 μmol/l) under the conditions of electroporation. Both cis- and trans-[Pt(PMSA)2I2] had pronounced cytotoxic effects (29 - 61 μmol/l against MDA-MB-231 cells).


2008 ◽  
Vol 22 (17) ◽  
pp. 1521-1534 ◽  
Author(s):  
Cecilia Díaz ◽  
Silvia Quesada ◽  
Oscar Brenes ◽  
Gilda Aguilar ◽  
José F. Cicció

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