Screening of North African Medicinal Plant Extracts for Cytotoxic Activity Against Tumor Cell Lines

2013 ◽  
Vol 3 (3) ◽  
pp. 310-332 ◽  
Author(s):  
Lamiae Belayachi
Keyword(s):  
Medicinal Plant ◽  
Tumor Cell ◽  
Cytotoxic Activity ◽  
Cell Lines ◽  
Plant Extracts ◽  
Tumor Cell Lines ◽  
North African ◽  
Medicinal Plant Extracts

Screening of Venezuelan Medicinal Plant Extracts for Cytostatic and Cytotoxic Activity Against Tumor Cell Lines

2012 ◽  
Vol 27 (4) ◽  
pp. 530-539 ◽  
Author(s):  
Peter Taylor ◽  
Miriam Arsenak ◽  
María Jesús Abad ◽  
Ángel Fernández ◽  
Balentina Milano ◽  
...  
Keyword(s):  
Medicinal Plant ◽  
Tumor Cell ◽  
Cytotoxic Activity ◽  
Cell Lines ◽  
Plant Extracts ◽  
Tumor Cell Lines ◽  
Medicinal Plant Extracts

Screening of Venezuelan medicinal plant extracts for cytostatic and cytotoxic activity against tumour cell lines

Planta Medica ◽  
2012 ◽  
Vol 78 (11) ◽  
Author(s):  
P Taylor ◽  
M Arsenak ◽  
MJ Abad ◽  
Á Fernández ◽  
R Gonto ◽  
...  
Keyword(s):  
Medicinal Plant ◽  
Cytotoxic Activity ◽  
Cell Lines ◽  
Plant Extracts ◽  
Tumour Cell ◽  
Medicinal Plant Extracts ◽  
Tumour Cell Lines

C-prenylated flavonoids with potential cytotoxic activity against solid tumor cell lines

2019 ◽  
Vol 18 (4) ◽  
pp. 1051-1100
Author(s):  
Lenka Molčanová ◽  
Dominika Janošíková ◽  
Stefano Dall´Acqua ◽  
Karel Šmejkal
Keyword(s):  
Tumor Cell ◽  
Cytotoxic Activity ◽  
Cell Lines ◽  
Solid Tumor ◽  
Tumor Cell Lines ◽  
Prenylated Flavonoids

Molecular modeling of cytotoxic activity of a new terpenoid-like bischalcone

2019 ◽  
Vol 43 (47) ◽  
pp. 18451-18460
Author(s):  
Lóide O. Sallum ◽  
Vera L. Siqueira ◽  
Jean M. F. Custodio ◽  
Nádia M. Borges ◽  
Aliny P. Lima ◽  
...  
Keyword(s):  
Molecular Docking ◽  
Molecular Modeling ◽  
Tumor Cell ◽  
Cytotoxic Activity ◽  
Cell Lines ◽  
Tumor Cell Lines

This study describes the synthesis and structure of (1E,4E)-1-(3-chlorophenyl)-5-(2,6,6-trimethylcyclohex-1-en-1-yl)penta-1,4-dien-3-one (BC I). This work evaluates molecular docking and cytotoxic activity against two tumor cell lines.

scholarly journals Selective cytotoxic activity of brefeldin A against human tumor cell lines.

1989 ◽  
Vol 42 (12) ◽  
pp. 1877-1878 ◽  
Author(s):  
SHIGETAKA ISHII ◽  
MIEKO NAGASAWA ◽  
YUKO KARIYA ◽  
HARUO YAMAMOTO
Keyword(s):  
Tumor Cell ◽  
Cytotoxic Activity ◽  
Cell Lines ◽  
Human Tumor ◽  
Brefeldin A ◽  
Tumor Cell Lines ◽  
Human Tumor Cell ◽  
Human Tumor Cell Lines

scholarly journals Synthesis and Characterization of New Palladium(II) Thiosemicarbazone Complexes and Their Cytotoxic Activity against Various Human Tumor Cell Lines

2013 ◽  
Vol 2013 ◽  
pp. 1-12 ◽  
Author(s):  
Wilfredo Hernández ◽  
Juan Paz ◽  
Fernando Carrasco ◽  
Abraham Vaisberg ◽  
Evgenia Spodine ◽  
...  
Keyword(s):  
Tumor Cell ◽  
Cytotoxic Activity ◽  
Cell Lines ◽  
Human Tumor ◽  
Tumor Cell Lines ◽  
Human Tumor Cell ◽  
Human Tumor Cell Lines ◽  
Thiosemicarbazone Complexes ◽  
Benzaldehyde Thiosemicarbazone

The palladium(II) bis-chelate complexes of the type [Pd(TSC1-5)2] (6–10), with their corresponding ligands 4-phenyl-1-(acetone)-thiosemicarbazone, HTSC1(1), 4-phenyl-1-(2′-chloro-benzaldehyde)-thiosemicarbazone, HTSC2(2), 4-phenyl-1-(3′-hydroxy-benzaldehyde)-thiosemicarbazone, HTSC3(3), 4-phenyl-1-(2′-naphthaldehyde)-thiosemicarbazone, HTSC4(4), and 4-phenyl-1-(1′-nitro-2′-naphthaldehyde)-thiosemicarbazone, HTSC5(5), were synthesized and characterized by elemental analysis and spectroscopic techniques (IR and1H- and13C-NMR). The molecular structure of HTSC3, HTSC4, and [Pd(TSC1)2] (6) have been determined by single crystal X-ray crystallography. Complex6shows a square planar geometry with two deprotonated ligands coordinated toPdIIthrough the azomethine nitrogen and thione sulfur atoms in acisarrangement. Thein vitrocytotoxic activity measurements indicate that the palladium(II) complexes (IC50=0.01–9.87 μM) exhibited higher antiproliferative activity than their free ligands (IC50=23.48–70.86 and >250 μM) against different types of human tumor cell lines. Among all the studied palladium(II) complexes, the [Pd(TSC3)2] (8) complex exhibited high antitumor activity on the DU145 prostate carcinoma and K562 chronic myelogenous leukemia cells, with low values of the inhibitory concentration (0.01 and 0.02 μM, resp.).Corrigendum to “Synthesis and Characterization of New Palladium(II) Thiosemicarbazone Complexes and Their Cytotoxic Activity against Various Human Tumor Cell Lines”

Synthesis and in vitro cytotoxic activity of novel hexahydro-2H-pyrido[1,2-b]isoquinolines against human brain tumor cell lines

1997 ◽  
Vol 7 (23) ◽  
pp. 2945-2950 ◽  
Author(s):  
Axel Monsees ◽  
Sabine Laschat ◽  
Marc Hotfilder ◽  
Johannes Wolff ◽  
Klaus Bergander ◽  
...  
Keyword(s):  
Brain Tumor ◽  
Tumor Cell ◽  
Human Brain ◽  
Cytotoxic Activity ◽  
Cell Lines ◽  
Tumor Cell Lines ◽  
Human Brain Tumor ◽  
Brain Tumor Cell

scholarly journals Antimycobacterial and cytotoxic activity of selected medicinal plant extracts

2016 ◽  
Vol 182 ◽  
pp. 10-15 ◽  
Author(s):  
Joseph M. Nguta ◽  
Regina Appiah-Opong ◽  
Alexander K. Nyarko ◽  
Dorothy Yeboah-Manu ◽  
Phyllis G.A. Addo ◽  
...  
Keyword(s):  
Medicinal Plant ◽  
Cytotoxic Activity ◽  
Plant Extracts ◽  
Medicinal Plant Extracts
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