scholarly journals Development of a Whole Bovine Long-term Organ Culture System that Retains Vertebral Bone for Intervertebral Disc Repair and Biomechanical Studies using PrimeGrowth Media

2016 ◽  
Vol 6 (1_suppl) ◽  
pp. s-0036-1582897-s-0036-1582897
Author(s):  
Michael Grant ◽  
Laura Epure ◽  
Omar Salem ◽  
Motaz Alaqeel ◽  
John Antoniou ◽  
...  
Keyword(s):  
Intervertebral Disc ◽  
Organ Culture ◽  
Culture System ◽  
Vertebral Bone ◽  
Organ Culture System ◽  
Disc Repair ◽  
Intervertebral Disc Repair

Development of an Organ Culture System for Long-Term Survival of the Intact Human Intervertebral Disc

Spine ◽  
2011 ◽  
Vol 36 (22) ◽  
pp. 1835-1842 ◽  
Author(s):  
Rahul Gawri ◽  
Fackson Mwale ◽  
Jean Ouellet ◽  
Peter J. Roughley ◽  
Thomas Steffen ◽  
...  
Keyword(s):  
Intervertebral Disc ◽  
Organ Culture ◽  
Culture System ◽  
Term Survival ◽  
Long Term Survival ◽  
Organ Culture System

Short Link N Stimulates Intervertebral Disc Repair in a Novel Long-Term Organ Culture Model that Includes the Bony Vertebrae

2016 ◽  
Vol 22 (21-22) ◽  
pp. 1252-1257 ◽  
Author(s):  
Nizar AlGarni ◽  
Michael P. Grant ◽  
Laura M. Epure ◽  
Omar Salem ◽  
Rakan Bokhari ◽  
...  
Keyword(s):  
Intervertebral Disc ◽  
Organ Culture ◽  
Culture Model ◽  
Disc Repair ◽  
Intervertebral Disc Repair ◽  
Short Link

scholarly journals An organ culture system to model early degenerative changes of the intervertebral disc II: profiling global gene expression changes

2013 ◽  
Vol 15 (5) ◽  
pp. R121 ◽  
Author(s):  
Dessislava Z Markova ◽  
Christopher K Kepler ◽  
Sankar Addya ◽  
Hallie B Murray ◽  
Alexander R Vaccaro ◽  
...  
Keyword(s):  
Gene Expression ◽  
Intervertebral Disc ◽  
Organ Culture ◽  
Culture System ◽  
Global Gene Expression ◽  
Degenerative Changes ◽  
Organ Culture System

scholarly journals Development of an intact intervertebral disc organ culture system in which degeneration can be induced as a prelude to studying repair potential

2011 ◽  
Vol 20 (8) ◽  
pp. 1244-1254 ◽  
Author(s):  
Bernice Jim ◽  
Thomas Steffen ◽  
Janet Moir ◽  
Peter Roughley ◽  
Lisbet Haglund
Keyword(s):  
Intervertebral Disc ◽  
Organ Culture ◽  
Culture System ◽  
Organ Culture System

Bench-Top Validation Tests for Tissue-Engineered Arteries

2000 ◽  
Author(s):  
Shawn Chin Quee ◽  
Hai-Chao Han ◽  
David N. Ku
Keyword(s):  
Organ Culture ◽  
Culture System ◽  
Comprehensive Evaluation ◽  
Ex Vivo ◽  
Vascular Grafts ◽  
Living System ◽  
Organ Culture System ◽  
Flow Pressure ◽  
Validation Tests

Abstract Standard tests are needed for evaluating and comparing the mechanical and biological functions of tissue engineered arteries and other vascular grafts. We propose an ex vivo organ culture system as a living system for testing tissue-engineered vascular grafts. This bench-top organ culture system mimics the physiological environment of arteries including the flow, pressure, and the axial stretch. Arterial mechanical properties and physiologic functions including compliance, burst pressure, and contractile functions can be assessed before an expensive long-term animal test is initiated. Test results of natural arteries indicate that organ culture is a valid model for comprehensive evaluation of tissue-engineered vascular grafts.

4:2898. Chondrocyte Based Gene Therapy for the Degenerating Intervertebral Disc in the Rabbit Disc Organ Culture System

2006 ◽  
Vol 6 (5) ◽  
pp. 48S
Author(s):  
Yejia Zhang ◽  
Howard S. An ◽  
Eugene Thonar ◽  
Theodore Oegema ◽  
Gunnar Andersson ◽  
...  
Keyword(s):  
Gene Therapy ◽  
Intervertebral Disc ◽  
Organ Culture ◽  
Culture System ◽  
Organ Culture System

scholarly journals Characterization of an in vitro intervertebral disc organ culture system

2007 ◽  
Vol 16 (7) ◽  
pp. 1029-1037 ◽  
Author(s):  
Casey L. Korecki ◽  
Jeffrey J. MacLean ◽  
James C. Iatridis
Keyword(s):  
Intervertebral Disc ◽  
Organ Culture ◽  
Culture System ◽  
Organ Culture System
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