Fe(BF4)2-Catalyzed Inter- and Intramolecular Carbonyl-Ene Reaction of Trifluoropyruvate
Inter- and intramolecular carbonyl-ene reactions have been developed using 5 mol% Fe(BF4)2 as catalyst, affording homoallylic alcohols in 36–87% isolated yields. This catalyst, prepared from FeCl2 and AgBF4, is the first FeII Lewis acid reported for the carbonyl-ene reaction using ethyl trifluoropyruvate. The method was successfully applied to the reaction of various 1,1-disubstituted alkenes with ethyl trifluoropyruvate and to the cyclization of citronellal.
1977 ◽
pp. 382-383
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2019 ◽
Vol 84
(3)
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pp. 1605-1613
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2011 ◽
Vol 353
(5)
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pp. 695-700
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1991 ◽
Vol 56
(16)
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pp. 4908-4913
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1996 ◽
Vol 51
(6)
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pp. 838-850
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