Copper-Catalyzed Oxidative Dimerization of 2-Oxindoles under Base-Free Conditions

Synlett ◽  
2018 ◽  
Vol 29 (11) ◽  
pp. 1485-1490 ◽  
Author(s):  
Wen-Ting Wei ◽  
Yi-Ling Huang ◽  
Wen-Hui Bao ◽  
Wei-Wei Ying ◽  
Wei-Ting Chen ◽  
...  
Keyword(s):  
Bond Formation ◽  
Radical Mechanism ◽  
Oxidative Dimerization ◽  
Radical Initiator ◽  
Tert Butyl ◽  
Simple Strategy ◽  
Efficient Route ◽  
Butyl Peroxide

A practical copper-catalyzed oxidative dimerization of 2-oxindoles using di-tert-butyl peroxide as the radical initiator under base-free conditions was achieved, which not only provided an efficient route to prepare various 3,3′-bioxindoles, but also represented a simple strategy for C(sp3)–H functionalization/C–C bond formation. A radical mechanism was proposed based on the reaction results and controlling experiments.

Copper/Di-tert-butyl Peroxide-Catalyzed Regioselective Hydroxyphosphorylation of 1,3-Enynes

Synthesis ◽  
2021 ◽  
Author(s):  
Shaoqun Zhu ◽  
Jiawei Wang ◽  
Bing Zhou ◽  
Hong Hou
Keyword(s):  
Functional Group ◽  
Catalytic Amount ◽  
Radical Reactions ◽  
Reaction Conditions ◽  
Radical Initiator ◽  
Tert Butyl ◽  
Butyl Peroxide

AbstractThe copper/di-tert-butyl peroxide-catalyzed regioselective hydroxyphosphorylation of 1,3-enynes is described. The advantages of the reported radical reactions are excellent functional group tolerance, the use of a catalytic amount of copper and di-tert-butyl peroxide ( t BuOO t Bu) as a radical initiator, and mild reaction conditions. The desired products are obtained in moderate to excellent yields after purification.

Iron-Catalyzed Carboiodination of Alkynes

Synthesis ◽  
2018 ◽  
Vol 50 (15) ◽  
pp. 2974-2980 ◽  
Author(s):  
You-Gui Li ◽  
Hongli Bao ◽  
Weili Deng ◽  
Yajun Li
Keyword(s):  
Room Temperature ◽  
Cyano Group ◽  
Alkyl Chains ◽  
Radical Initiator ◽  
Tert Butyl ◽  
Butyl Peroxide ◽  
Alkyl Iodides ◽  
Vinyl Iodides ◽  
Fluoroalkyl Group

An iron-catalyzed carboiodination of alkynes with alkyl iodides­ at room temperature was developed. This method could provide synthetically useful vinyl iodides with general alkyl chains, fluoroalkyl group, ester, and cyano group. Conjugated alkynes or unconjugated alkynes were both suitable for this transformation. A radical pathway was proposed for the mechanism and acetyl tert-butyl peroxide was selected as the radical initiator. Alkenes could also be applied to this chemistry and produce more complex alkyl iodides.

Fundamental Thermal Hazard Investigation for Tert-Butyl Peroxide Reactor Using DSC and TGA Techniques

2011 ◽  
Vol 21 (1) ◽  
pp. 53-63 ◽  
Author(s):  
Chien-Jung Chen ◽  
Jen-Hao Chi ◽  
Sheng-Hung Wu ◽  
Cheng-Tung Chen ◽  
Hsiu-Fen Tsai
Keyword(s):  
Thermal Hazard ◽  
Tert Butyl ◽  
Butyl Peroxide

Energy partitioning on photolysis of di-tert-butyl peroxide

1971 ◽  
Vol 75 (24) ◽  
pp. 3651-3655 ◽  
Author(s):  
F. H. Dorer ◽  
S. N. Johnson
Keyword(s):  
Energy Partitioning ◽  
Tert Butyl ◽  
Butyl Peroxide

ChemInform Abstract: MANUFACTURE OF DIMETHYL(VINYLETHYNYL)METHYL TERT-BUTYL PEROXIDE

1979 ◽  
Vol 10 (48) ◽  
Author(s):  
M. R. VILENSKAYA ◽  
D. S. KARAMOV ◽  
E. I. SOROKIN ◽  
G. A. PETROVSKAYA ◽  
V. A. PUCHIN
Keyword(s):  
Tert Butyl ◽  
Butyl Peroxide

ChemInform Abstract: Reaction of Chloromethylsilanes with Adamantane and 1,3-Dimethyladamantane in the Presence of tert-Butyl Peroxide.

ChemInform ◽  
1988 ◽  
Vol 19 (24) ◽  
Author(s):  
N. S. FEDOTOV ◽  
E. V. GRISHINA ◽  
V. D. SHELUDYAKOV ◽  
A. A. BERNADSKII ◽  
V. N. BOCHKAREV
Keyword(s):  
Tert Butyl ◽  
Butyl Peroxide

Dirhodium(II)-Catalyzed Diamination Reaction via a Free Radical Pathway

2021 ◽  
Author(s):  
Zhiying Fan ◽  
Zhifan Wang ◽  
Ruoyi Shi ◽  
Yuanhua Wang
Keyword(s):  
Free Radical ◽  
Bond Formation ◽  
Mechanistic Study ◽  
Radical Mechanism ◽  
Free Radical Mechanism

Unlike C-N bond formation with classical dirhodium(II)-nitrenoids as the key intermediate, dirhodium(II)-catalyzed 1,2-and 1,3-diamination reactions are realized by a free radical mechanism. A mechanistic study revealed that the reactions undergo...

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