scholarly journals Incidence of Allergic Fungal Sinusitis among patients with nasal polyps and role of Lund-Mackay scoring in its diagnosis.

2020 ◽  
Author(s):  
R Dhanani ◽  
H Pasha ◽  
S Khalid ◽  
M Ikram
Keyword(s):  
Nasal Polyps ◽  
Fungal Sinusitis ◽  
Allergic Fungal Sinusitis

scholarly journals Role of Fungi in Allergic Fungal Sinusitis and Chronic Rhinosinusitis

2000 ◽  
Vol 75 (5) ◽  
pp. 540-541
Author(s):  
Jens U. Ponikau ◽  
David A. Sherris ◽  
Eugene B. Kern
Keyword(s):  
Chronic Rhinosinusitis ◽  
Fungal Sinusitis ◽  
Allergic Fungal Sinusitis

Response of Visual Loss in Allergic Fungal Sinusitis to Oral Corticosteroids

2005 ◽  
Vol 114 (3) ◽  
pp. 247-249 ◽  
Author(s):  
Scott M. Graham ◽  
Keith D. Carter
Keyword(s):  
Visual Loss ◽  
Fungal Sinusitis ◽  
Allergic Fungal Sinusitis ◽  
Medical Comorbidities ◽  
Oral Corticosteroids

Visual loss associated with allergic fungal sinusitis is most often treated with surgery followed by oral corticosteroids. A case is presented in which, because of substantial medical comorbidities, surgery could not be initially performed and the visual loss was corrected with prednisone alone. This case serves to reinforce the central role of corticosteroids in treatment of this enigmatic condition.

scholarly journals Study to Determine the Incidence of Allergic Fungal Sinusitis among Patients with Nasal Polyps and Its Related Risk Factors

2021 ◽  
Vol 15 (7) ◽  
pp. 1860-1863
Author(s):  
Bakht Zada ◽  
Ejaz Ahmed ◽  
Muhammad Habib ◽  
Zafar Iqbal ◽  
Rehan Saleem ◽  
...  
Keyword(s):  
Risk Factors ◽  
Nasal Septum ◽  
Nasal Polyps ◽  
Bone Erosion ◽  
Histopathological Examination ◽  
Sinus Surgery ◽  
Fungal Sinusitis ◽  
Deviated Nasal Septum ◽  
Allergic Fungal Sinusitis ◽  
Turbinate Hypertrophy

Aim: To govern the incidence of allergic fungal sinusitis in patients with nasal polyposis. Various anatomical risk factors were also investigated, including turbinate hypertrophy, deviated nasal septum and comorbidities such as asthma and diabetes. Study Design: This is a Descriptive cross-sectional study. Place and duration of study:The study was conducted at ENT Head &Neck Surgery department, Lady Reading Hospital MTI, Peshawar and Azra Nahid Medical College, Lahore for the duration of six months from May 2020 to October 2020. Methods: 110 patients with nasal polyps were evaluated and operated on. Samples were sent for histopathological examination and culture. All patients were assessed with clinical examination and detailed history. Laboratory tests were performed including complete blood counts, urea, electrolytes, ECG and chest radiographs for the suitability of general anesthesia as a prerequisite for surgery. In 95% of cases, computed tomography was recommended to check for sinus involvement, bone erosion, osteo-hypertrophic complex, turbinate hypertrophy, nasal septal deviation, and intracranial and intra-orbital enlargement. MRI examinations were also recommended in cases of suspected intraocular and intracranial disease (5%). Data was scrutinized on a computer using SPSS version 22.0. Results:Of the 110 patients, 65 were male and 45 were female, with a mean age of 1and ranged from 7 to 80 years. All patients had nasal polyps. The incidence of AFS was approximately 29.1% and the remaining 78 had a different pathology. Major deviation of the nasal septum and bilateral hypertrophy of the inferior turbinate’s were observed in 6 (18.7%) and 4 (12.5%) patients, respectively. Unilateral nasal polyps were observed in 7 (21.9%) patients and bilateral nasal polyps in 18 (52.3%). 19/32 (59.4%) of the cases underwent functional endoscopic surgery of the paranasal sinuses, and in 6 (18.7%) external fronto-ethmoidectomy. Two patients underwent nasal ethmoidectomy. Septoplasty and endoscopic sinus surgery were performed in a total of 3 (9.37%) cases. Key words:Allergic bronchopulmonary aspergillosis (ABPA), Allergic fungal sinusitis (AFS).

Allergic Mucin With and Without Fungus

2001 ◽  
Vol 125 (11) ◽  
pp. 1442-1447
Author(s):  
Jonathan F. Lara ◽  
J. Daniel Gomez
Keyword(s):  
Tertiary Care ◽  
Fungal Sinusitis ◽  
Allergic Fungal Sinusitis ◽  
Radiographic Findings ◽  
Care Institution ◽  
Tertiary Care Institution ◽  
Allergic Mucin ◽  
And Gender

Abstract Context.—Allergic mucin, a lamellated collection of inspissated inflammatory debris, has been a hallmark of allergic fungal sinusitis. While its identification is a clue for pathologists to search for fungi, and directs clinicians toward specific therapy and follow-up, recent reports describe cases with allergic mucin but without concomitant fungus. The absence of such organisms in otherwise typical allergic mucin brings into question the role of fungi in allergic fungal sinusitis. Objectives.—To study clinical and pathologic differences between patients with allergic mucin in surgical nasal resection specimens and to elucidate the role of fungus in allergic sinusitis. Design.—Patients with histologic evidence of allergic mucin, with and without fungus, were identified and retrieved from the surgical pathology files of a tertiary-care institution. The patients were separated into 2 groups for analysis, and their clinical and pathologic findings were reviewed and compared. Setting.—Tertiary-care institution. Patients.—All patients who underwent sinus mucosal resection between 1992 and 1998. Results.—Clinical presentation and radiographic findings were similar in both groups. Incidence, age, and gender distribution were similar to data reported previously. However, the amount of allergic mucin was much greater in the group with fungus than in the group without fungus, which to our knowledge is an unreported observation to date. Conclusion.—The presence of allergic mucin is not unique to allergic fungal sinusitis, but rather is the result of a process that could have other etiologies. While perhaps not always causative to the disease, the fungus continues to fuel the process and is likely an entrapped bystander. Allergic fungal sinusitis is more appropriately termed allergic mucinous sinusitis or eosinophilic mucinous rhinosinusitis.

Nasal polyps: Still more questions than answers

2003 ◽  
Vol 117 (1) ◽  
pp. 1-9 ◽  
Author(s):  
Neil D. Bateman ◽  
Colm Fahy ◽  
Timothy J. Woolford
Keyword(s):  
Surgical Treatment ◽  
Nasal Polyps ◽  
Fungal Spores ◽  
Extracellular Fluid ◽  
Inflammatory Cells ◽  
Preliminary Evidence ◽  
Good Evidence ◽  
Conclusive Evidence ◽  
Fungal Sinusitis ◽  
Allergic Fungal Sinusitis

Nasal polyps are common, affecting one to four per cent of the population. Their cause, however, remains unknown and it is possible that it is not the same in all patients. They have a clear association with asthma, aspirin sensitivity and cystic fibrosis. Histologically they demonstrate large quantities of extracellular fluid, mast cell degranulation and an infiltrate of inflammatory cells, usually eosinophils. While this appearance would suggest an allergic pathology there is little conclusive evidence to support this in most patients. There is, however, some preliminary evidence to suggest that a local allergic process could be the cause. While allergic fungal sinusitis is a well defined clinical entity with recognized diagnostic criteria the ubiquitous nature of fungal spores makes the role of fungal infection in patients with nasal polyps difficult to determine and currently this remains unclear.Surgical treatment of nasal polyps has declined in recent years as the benefits of medical treatment have become increasingly recognized. There is good evidence to support the use of corticosteroids both as a primary and post-operative treatment in the majority of patients. Other medical treatments require further evaluation before they could be considered a viable alternative to steroids. Assessment of the literature regarding surgical intervention is difficult and there is little evidence on which to base a surgical treatment philosophy. The authors believe that an endoscopic approach using a microdebrider facilitates accurate removal of polyps with preservation of normal anatomy.

scholarly journals The Role of CT Scan and Histopathology in Diagnosis of Allergic Fungal Sinusitis

2014 ◽  
Vol 7 (3) ◽  
pp. 117-120
Author(s):  
Bhanu Bhanu Bhardwaj ◽  
Jaskaran Singh Gill ◽  
Tanya Singh
Keyword(s):  
Ct Scan ◽  
Preoperative Diagnosis ◽  
Definitive Diagnosis ◽  
Fungal Sinusitis ◽  
Allergic Fungal Sinusitis ◽  
Diagnostic Modality ◽  
Preoperative Diagnostic ◽  
A Prospective Study ◽  
Histological Verification

ABSTRACT Allergic fungal sinusitis is the disease with emerging incidence in last decade. The diagnosis of AFS requires a combination of clinical, radiographic, microbiological and histopathological information. CT scan findings in AFS are considered important in preoperative diagnosis but definitive diagnosis requires histological verification. The role of CT scan as the preoperative diagnostic modality in AFS has been analyzed in 50 patients in a prospective study conducted at our institute and results have been very assuring. This article will surely satisfy many inquisitive minds about the speculations regarding the diagnosis of AFS. How to cite this article Bhardwaj BB, Gill JS, Singh T. The Role of CT Scan and Histopathology in Diagnosis of Allergic Fungal Sinusitis. Clin Rhinol An Int J 2014;7(3):117-120.

scholarly journals POST-OPERATIVE MANAGEMENT OF ALLERGIC FUNGAL SINUSITIS (ASF): ROLE OF ITRACONAZOLE

2014 ◽  
Vol 3 (32) ◽  
pp. 8729-8734
Author(s):  
Kanchan S Dhote ◽  
Priti R Dhoke ◽  
Harkare V V ◽  
Deosthale N V ◽  
Sonali P Khadakkar
Keyword(s):  
Operative Management ◽  
Fungal Sinusitis ◽  
Allergic Fungal Sinusitis

The Role of Powered Instrumentation in the Surgical Treatment of Allergic Fungal Sinusitis

1998 ◽  
Vol 77 (8) ◽  
pp. 678-682 ◽  
Author(s):  
Joseph P. Mirante ◽  
John H. Krouse ◽  
Michael A. Munier ◽  
Dewey A. Christmas
Keyword(s):  
Surgical Treatment ◽  
Sinus Surgery ◽  
Comprehensive Treatment ◽  
Fungal Sinusitis ◽  
Allergic Fungal Sinusitis ◽  
Chronic Disorder ◽  
Minimal Trauma ◽  
Surgical Field ◽  
Nose And Sinuses

Allergic fungal sinusitis is a chronic disorder that is being more frequently recognized by otolaryngologists. It is a recurrent illness characterized by frequent exacerbations, and requires aggressive medical and surgical treatment. When surgical therapy is employed, it is necessary to ensure adequate debridement and removal of edematous tissue. We have been using powered dissection as our primary method in sinus surgery over the past three years. We have treated 11 patients with allergic fungal sinusitis, and find powered instrumentation to be very effective in removing the polypoid tissue from the nose and sinuses, and in providing a clear surgical field. The procedure can be performed safely, with minimal trauma to normal tissue. We believe that the use of powered dissection greatly enhances the comprehensive treatment of allergic fungal sinusitis.

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