MBOAT7 rs641738 POLYMORPHISM IS LINKED TO ALTERED PORTAL BLOOD FLOW ASSESSED USING 13C METHACETIN TEST

ABSTRACT: Pulsed Doppler ultrasound was used to evaluate portal blood flow, portal velocity and portal congestion index in 24 healthy sheep divided into groups (lambs, yearlings and ewes), according to age. Measurements were performed at the 11th right intercostal space using ideal insonation angle and uniform insonation method. Mean values obtained in each group were compared with one-way ANOVA, followed by Tukey post-hoc test. Portal velocity and portal blood flow were statistically similar between the groups (P>0.05). Mean portal velocity were 17.75; 17.13 and 16.75; while mean portal blood flow were 26.65; 31.04 and 24.32 for lambs, yearlings and ewes, respectively. Portal congestion index was statistically distinct between the groups and values for lambs, yearlings and ewes were 0.009; 0.058 and 0.09, respectively (P<0.01). Statistical differences were observed in portal vein diameter, portal vein area and portal congestion index between the groups, presumably due to influence of weight and not to age.

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Autonomic control of renal portal blood flow in the domestic fowl

Cellular and Molecular Life Sciences ◽

10.1007/bf02326779 ◽

1975 ◽

Vol 31 (10) ◽

pp. 1177-1178 ◽

Cited By ~ 7

Author(s):

T. Bennett ◽

T. Malmfors

Keyword(s):

Blood Flow ◽

Domestic Fowl ◽

Portal Blood Flow ◽

Autonomic Control ◽

Portal Blood

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Measurement of portal blood flow by an ultrasonic “duplex” system composed of a pulsed Doppler flowmeter and a linear-type real time B mode electroscanner

Gastroenterologia Japonica ◽

10.1007/bf02918854 ◽

1988 ◽

Vol 23 (1) ◽

pp. 37-43 ◽

Cited By ~ 4

Author(s):

Shigehiro Shiraki ◽

Katsuhiko Tsukada ◽

Norishige Ozeki ◽

Toshihiko Takeuchi ◽

Kazuo Gotoh ◽

...

Keyword(s):

Blood Flow ◽

Real Time ◽

Portal Blood Flow ◽

Portal Blood ◽

Pulsed Doppler ◽

Duplex System ◽

Linear Type ◽

Doppler Flowmeter

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Effect of the site of infusion of para-aminohippuric acid (PAH) on portal blood flow

Annales de Zootechnie ◽

10.1051/animres:199505250 ◽

1995 ◽

Vol 44 (Suppl. 1) ◽

pp. 285-285

Author(s):

LM Zeoula ◽

C. Duvaux-Ponter ◽

I. Ortigues ◽

J. Lefaivre ◽

D. Sauvant ◽

...

Keyword(s):

Blood Flow ◽

Portal Blood Flow ◽

Portal Blood

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Correction of extrahepatic portal hypertension in pediatric patient after liver transplantation

Russian Journal of Transplantology and Artificial Organs ◽

10.15825/1995-1191-2017-1-47-51 ◽

2017 ◽

Vol 19 (1) ◽

pp. 47-51

Author(s):

A. R. Monakhov ◽

B. L. Mironkov ◽

T. A. Dzhanbekov ◽

K. O. Semash ◽

Kh. M. Khizroev ◽

...

Keyword(s):

Liver Transplantation ◽

Blood Flow ◽

Portal Hypertension ◽

Portal Vein ◽

Pediatric Patient ◽

Portal Blood Flow ◽

Portal Blood ◽

Positive Trend ◽

Portal Vein Stenosis ◽

Vein Stenosis

Introduction. Liver transplantation is a multi-component and complex type of operative treatment. Patients undergoing such a treatment sometimes are getting various complications. One of these complications is a portal hypertension associated with portal vein stenosis.Materials and methods. In 6 years after the left lateral section transplantation from living donor in a pediatric patient the signs of portal hypertension were observed. Stenosis of the portal vein was revealed. Due to this fact percutaneous transhepatic correction of portal vein stenosis was performed.Results. As a result of the correction of portal blood flow in the patient a positive trend was noted. According to the laboratory and instrumental methods of examination the graft had a normal function, portal blood flow was adequate. In order to control the stent patency Doppler ultrasound and MSCT of the abdominal cavity with intravenous bolus contrasting were performed. Due to these examinations the stent function was good, the rate of blood flow in the portal vein due to Doppler data has reached 80 cm/sec, and a decrease of the spleen size was noted.Conclusion. Diagnosis and timely detection of portal vein stenosis in patients after liver transplantation are very important for the preservation of graft function and for the prevention of portal hypertension. In order to do that, ultrasound Doppler fluorimetry examination needs to be performed to each patient after liver transplantation. In cases of violation of the blood flow in the portal vein CT angiography performance is needed. Percutaneous transhepatic stenting of portal vein is a minimally invasive and highly effective method of correction of portal hypertension. Antiplatelet therapy and platelet aggregation control are the prerequisites for successful stent function.

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