A pilot evaluation of alfentanil-induced miosis as a noninvasive probe for hepatic cytochrome P450 3A4 (CYP3A4) activity in humans

2001 ◽  
Vol 70 (6) ◽  
pp. 505-517 ◽  
Author(s):  
S Phimmasone
Keyword(s):  
Cytochrome P450 ◽  
Cytochrome P450 3A4 ◽  
Cyp3a4 Activity ◽  
Hepatic Cytochrome

Interaction of methadone with substrates of human hepatic cytochrome P450 3A4

Toxicology ◽  
1997 ◽  
Vol 117 (1) ◽  
pp. 13-23 ◽  
Author(s):  
C. Iribarne ◽  
Y. Dréano ◽  
L.G. Bardou ◽  
J.F. Ménez ◽  
F. Berthou
Keyword(s):  
Cytochrome P450 ◽  
Cytochrome P450 3A4 ◽  
Hepatic Cytochrome

Enhanced intrinsic CYP3A4 activity in human hepatic C3A cells with optically controlled CRISPR/dCas9 activator complex

2018 ◽  
Vol 10 (12) ◽  
pp. 780-790
Author(s):  
Shuo Han ◽  
Shiruo Wei ◽  
Xuan Wang ◽  
Xu Han ◽  
Mingzhi Zhang ◽  
...  
Keyword(s):  
Enzyme Activity ◽  
Cytochrome P450 ◽  
Bioartificial Liver ◽  
Liver Development ◽  
Cytochrome P450 3A4 ◽  
Cyp3a4 Activity ◽  
Cyp3a4 Enzyme ◽  
Activator Complex

Human hepatic C3A cells have been applied in bioartificial liver development, although these cells display low intrinsic cytochrome P450 3A4 (CYP3A4) enzyme activity.

Growth Hormone Determines Sexual Dimorphism of Hepatic Cytochrome P450 3A4 Expression in Transgenic Mice

2005 ◽  
Vol 316 (3) ◽  
pp. 1328-1334 ◽  
Author(s):  
Connie Cheung ◽  
Ai-Ming Yu ◽  
Chong-Sheng Chen ◽  
Kristopher W. Krausz ◽  
Linda G. Byrd ◽  
...  
Keyword(s):  
Growth Hormone ◽  
Cytochrome P450 ◽  
Sexual Dimorphism ◽  
Transgenic Mice ◽  
Cytochrome P450 3A4 ◽  
Hepatic Cytochrome

In vivoEffect of I'm-Yunity™ on Hepatic Cytochrome P450 3A4

2007 ◽  
Vol 7 (1) ◽  
pp. 39-56 ◽  
Author(s):  
Jean Paul A. Nicandro ◽  
Candy Tsourounis ◽  
Lynda Frassetto ◽  
B. Joseph Guglielmo
Keyword(s):  
Cytochrome P450 ◽  
Cytochrome P450 3A4 ◽  
Hepatic Cytochrome

Mechanism-based inhibition of Alantolactone on human cytochrome P450 3A4 in vitro and activity of hepatic cytochrome P450 in mice

2015 ◽  
Vol 168 ◽  
pp. 146-149 ◽  
Author(s):  
Chong-Zhen Qin ◽  
Qiao-Li Lv ◽  
Na-Yiyuan Wu ◽  
Lin Cheng ◽  
Yun-Chen Chu ◽  
...  
Keyword(s):  
Cytochrome P450 ◽  
Cytochrome P450 3A4 ◽  
Human Cytochrome ◽  
Hepatic Cytochrome
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