Ketoconazole (K) inhibition of intestinal and hepatic cytochrome P450 3A4 (CYP3A4) activity using midazolam (M) as an in vivo probe

1999 ◽  
Vol 65 (2) ◽  
pp. 172-172 ◽  
Author(s):  
S TSUNODA ◽  
R VELEZ ◽  
D GREENBLATT
Keyword(s):  
Cytochrome P450 ◽  
Cytochrome P450 3A4 ◽  
Cyp3a4 Activity ◽  
Hepatic Cytochrome

In vivo Effect of I'm-Yunity™ on Hepatic Cytochrome P450 3A4

2007 ◽  
Vol 7 (1) ◽  
pp. 39-56 ◽  
Author(s):  
Jean Paul Nicandro ◽  
Candy Tsourounis ◽  
Lynda Frassetto ◽  
B. Joseph Guglielmo
Keyword(s):  
Cytochrome P450 ◽  
Cytochrome P450 3A4 ◽  
Hepatic Cytochrome

Interaction of methadone with substrates of human hepatic cytochrome P450 3A4

Toxicology ◽  
1997 ◽  
Vol 117 (1) ◽  
pp. 13-23 ◽  
Author(s):  
C. Iribarne ◽  
Y. Dréano ◽  
L.G. Bardou ◽  
J.F. Ménez ◽  
F. Berthou
Keyword(s):  
Cytochrome P450 ◽  
Cytochrome P450 3A4 ◽  
Hepatic Cytochrome

Enhanced intrinsic CYP3A4 activity in human hepatic C3A cells with optically controlled CRISPR/dCas9 activator complex

2018 ◽  
Vol 10 (12) ◽  
pp. 780-790
Author(s):  
Shuo Han ◽  
Shiruo Wei ◽  
Xuan Wang ◽  
Xu Han ◽  
Mingzhi Zhang ◽  
...  
Keyword(s):  
Enzyme Activity ◽  
Cytochrome P450 ◽  
Bioartificial Liver ◽  
Liver Development ◽  
Cytochrome P450 3A4 ◽  
Cyp3a4 Activity ◽  
Cyp3a4 Enzyme ◽  
Activator Complex

Human hepatic C3A cells have been applied in bioartificial liver development, although these cells display low intrinsic cytochrome P450 3A4 (CYP3A4) enzyme activity.

Cytochrome b5 Is a Major Determinant of Human Cytochrome P450 CYP2D6 and CYP3A4 Activity In Vivo

2015 ◽  
Vol 87 (4) ◽  
pp. 733-739 ◽  
Author(s):  
Colin J. Henderson ◽  
Lesley A. McLaughlin ◽  
Nico Scheer ◽  
Lesley A. Stanley ◽  
C. Roland Wolf
Keyword(s):  
Cytochrome P450 ◽  
Cytochrome B5 ◽  
Major Determinant ◽  
Cyp3a4 Activity ◽  
Human Cytochrome

Growth Hormone Determines Sexual Dimorphism of Hepatic Cytochrome P450 3A4 Expression in Transgenic Mice

2005 ◽  
Vol 316 (3) ◽  
pp. 1328-1334 ◽  
Author(s):  
Connie Cheung ◽  
Ai-Ming Yu ◽  
Chong-Sheng Chen ◽  
Kristopher W. Krausz ◽  
Linda G. Byrd ◽  
...  
Keyword(s):  
Growth Hormone ◽  
Cytochrome P450 ◽  
Sexual Dimorphism ◽  
Transgenic Mice ◽  
Cytochrome P450 3A4 ◽  
Hepatic Cytochrome
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