scholarly journals Effects of Growth Hormone Administration on Wool Growth in Merino Sheep

1988 ◽  
Vol 41 (2) ◽  
pp. 177 ◽  
Author(s):  
PC Wynn ◽  
ALC Wallace ◽  
AC Kirby ◽  
EF Annison

The effects of daily administration of 10 mg of highly purified ovine growth hormone (GH) for a period of 4 weeks on wool growth have been measured in 12 Merino ewes fed either a calculated maintenance energy intake or 1�6 times this amount (six on each ration). Concentrations of hormones, glucose, urea, a-amino N and amino acids in the blood were monitored and faeces and urine collected for measurement of nitrogen balance.

1992 ◽  
Vol 2 (7) ◽  
pp. 1171-1177
Author(s):  
T C Welbourne ◽  
K Horton ◽  
M J Cronin

Growth hormone administration effects a positive nitrogen balance in part by recycling glutamine nitrogen as glutamate at the expense of ureagenesis. The study presented here focuses on the response of the isolated perfused hypophysectomized rat kidney to acute growth hormone administration during infusions of either glutamine or glutamate. Growth hormone at 50 nM acutely decreases the renal utilization of both glutamine and glutamate while enhancing reabsorption of the latter. During glutamine infusions of either 1,000 or 500 nmol/min, growth hormone markedly reduced net glutamine utilization by 55% at the high loads and reversed utilization to release at the lower load; associated with decreased glutamine utilization was reduced ammonium production and increased glutamate release. Although glutamine reabsorption was unchanged, glutamate reabsorption increased and NH4+ excretion decreased. During glutamate infusion of 180 nmol/min, growth hormone reduced glutamate utilization 66%, the residual utilization matching increased glutamate reabsorption was associated with enhanced bicarbonate reabsorption and a redistribution of NH4+ release into the urine; all three responses were eliminated by amiloride. These responses to growth hormone are consonant with reduced glutamate oxidation underlying decreased glutamine utilization and accelerated luminal Na+-H+ exchange mediating luminal transport, events that are conceivably interrelated.


Metabolism ◽  
1989 ◽  
Vol 38 (3) ◽  
pp. 197-203 ◽  
Author(s):  
William T. Dahms ◽  
Ruth P. Owens ◽  
Satish C. Kalhan ◽  
Douglas S. Kerr ◽  
Robert K. Danish

1986 ◽  
Vol 116 (1) ◽  
pp. 157-163 ◽  
Author(s):  
Joan H. Eisemann ◽  
Henry F. Tyrrell ◽  
Andrew C. Hammond ◽  
Paul J. Reynolds ◽  
Dale E. Bauman ◽  
...  

1999 ◽  
Vol 46 (4) ◽  
pp. 605-612 ◽  
Author(s):  
TOSHIAKI TANAKA ◽  
YOSHIKI SEINO ◽  
KENJI FUJIEDA ◽  
YUTAKA IGARASHI ◽  
SUSUMU YOKOYA ◽  
...  

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