Caspase-1 and -3 are sequentially activated in motor neuron death in Cu,Zn superoxide dismutase-mediated familial amyotrophic lateral sclerosis

Proceedings of the National Academy of Sciences ◽

10.1073/pnas.240305897 ◽

2000 ◽

Vol 97 (25) ◽

pp. 13901-13906 ◽

Author(s):

P. Pasinelli ◽

M. K. Houseweart ◽

R. H. Brown ◽

D. W. Cleveland

Keyword(s):

Amyotrophic Lateral Sclerosis ◽

Superoxide Dismutase ◽

Motor Neuron ◽

Familial Amyotrophic Lateral Sclerosis ◽

Neuron Death ◽

Caspase 1 ◽

Motor Neuron Death ◽

Lateral Sclerosis

Download Full-text

Proteasomal inhibition by misfolded mutant superoxide dismutase 1 induces selective motor neuron death in familial amyotrophic lateral sclerosis

Journal of Neurochemistry ◽

10.1046/j.1471-4159.2002.01211.x ◽

2002 ◽

Vol 83 (5) ◽

pp. 1030-1042 ◽

Author(s):

Makoto Urushitani ◽

Junko Kurisu ◽

Kayoko Tsukita ◽

Ryosuke Takahashi

Keyword(s):

Amyotrophic Lateral Sclerosis ◽

Superoxide Dismutase ◽

Motor Neuron ◽

Familial Amyotrophic Lateral Sclerosis ◽

Superoxide Dismutase 1 ◽

Neuron Death ◽

Proteasomal Inhibition ◽

Motor Neuron Death ◽

Lateral Sclerosis

Download Full-text

Cellular and molecular mechanisms of motor neuron death in amyotrophic lateral sclerosis

10.3389/978-2-88919-376-9 ◽

2015 ◽

Keyword(s):

Amyotrophic Lateral Sclerosis ◽

Motor Neuron ◽

Molecular Mechanisms ◽

Neuron Death ◽

Motor Neuron Death ◽

Lateral Sclerosis

Download Full-text

Familial Amyotrophic Lateral Sclerosis with a Novel G85S Mutation of Superoxide Dismutase 1 Gene: Clinical Features of Lower Motor Neuron Disease

Internal Medicine ◽

10.2169/internalmedicine.49.2720 ◽

2010 ◽

Vol 49 (2) ◽

pp. 183-186 ◽

Author(s):

Takanori Takazawa ◽

Ken Ikeda ◽

Takehisa Hirayama ◽

Kiyokazu Kawabe ◽

Yoshikazu Nakamura ◽

...

Keyword(s):

Amyotrophic Lateral Sclerosis ◽

Superoxide Dismutase ◽

Motor Neuron ◽

Motor Neuron Disease ◽

Clinical Features ◽

Lower Motor Neuron ◽

Familial Amyotrophic Lateral Sclerosis ◽

Superoxide Dismutase 1 ◽

Lower Motor Neuron Disease ◽

Lateral Sclerosis

Download Full-text

Low molecular weight species of TDP-43 generated by abnormal splicing form inclusions in amyotrophic lateral sclerosis and result in motor neuron death

Acta Neuropathologica ◽

10.1007/s00401-015-1412-5 ◽

2015 ◽

Vol 130 (1) ◽

pp. 49-61 ◽

Author(s):

Shangxi Xiao ◽

Teresa Sanelli ◽

Helen Chiang ◽

Yulong Sun ◽

Avijit Chakrabartty ◽

...

Keyword(s):

Molecular Weight ◽

Amyotrophic Lateral Sclerosis ◽

Motor Neuron ◽

Low Molecular Weight ◽

Neuron Death ◽

Motor Neuron Death ◽

Lateral Sclerosis

Download Full-text

Backdoor intrusion: retrotoxicity can explain targeted motor neuron death in amyotrophic lateral sclerosis

Neural Regeneration Research ◽

10.4103/1673-5374.301037 ◽

2021 ◽

Vol 16 (7) ◽

pp. 1448

Author(s):

RandallD McKinnon

Keyword(s):

Amyotrophic Lateral Sclerosis ◽

Motor Neuron ◽

Neuron Death ◽

Motor Neuron Death ◽

Lateral Sclerosis

Download Full-text

Mechanisms for neuronal degeneration in amyotrophic lateral sclerosis and in models of motor neuron death (Review).

International Journal of Molecular Medicine ◽

10.3892/ijmm.5.1.3 ◽

2000 ◽

Author(s):

L J Martin ◽

A C Price ◽

A Kaiser ◽

A Y Shaikh ◽

Z Liu

Keyword(s):

Amyotrophic Lateral Sclerosis ◽

Motor Neuron ◽

Neuronal Degeneration ◽

Neuron Death ◽

Motor Neuron Death ◽

Lateral Sclerosis

Download Full-text

Cellular and molecular mechanisms of motor neuron death in amyotrophic lateral sclerosis: a perspective

Frontiers in Cellular Neuroscience ◽

10.3389/fncel.2014.00241 ◽

2014 ◽

Vol 8 ◽

Author(s):

Ricardo Tapia

Keyword(s):

Amyotrophic Lateral Sclerosis ◽

Motor Neuron ◽

Molecular Mechanisms ◽

Neuron Death ◽

Motor Neuron Death ◽

Lateral Sclerosis

Download Full-text

Ferroptosis mediates selective motor neuron death in amyotrophic lateral sclerosis

Cell Death and Differentiation ◽

10.1038/s41418-021-00910-z ◽

2021 ◽

Author(s):

Taide Wang ◽

Doris Tomas ◽

Nirma D. Perera ◽

Brittany Cuic ◽

Sophia Luikinga ◽

...

Keyword(s):

Amyotrophic Lateral Sclerosis ◽

Motor Neuron ◽

Neuron Death ◽

Motor Neuron Death ◽

Lateral Sclerosis

Download Full-text

Galactooligosaccharide improves the animal survival and alleviates motor neuron death in SOD1G93A mouse model of amyotrophic lateral sclerosis

Neuroscience ◽

10.1016/j.neuroscience.2013.05.002 ◽

2013 ◽

Vol 246 ◽

pp. 281-290 ◽

Author(s):

L. Song ◽

Y. Gao ◽

X. Zhang ◽

W. Le

Keyword(s):

Amyotrophic Lateral Sclerosis ◽

Mouse Model ◽

Motor Neuron ◽

Neuron Death ◽

Animal Survival ◽

Motor Neuron Death ◽

Sod1g93a Mouse ◽

Lateral Sclerosis

Download Full-text

Extracellular ATP and the P2X7 receptor in astrocyte-mediated motor neuron death: implications for amyotrophic lateral sclerosis

Journal of Neuroinflammation ◽

10.1186/1742-2094-7-33 ◽

2010 ◽

Vol 7 (1) ◽

pp. 33 ◽

Author(s):

Mandi Gandelman ◽

Hugo Peluffo ◽

Joseph S Beckman ◽

Patricia Cassina ◽

Luis Barbeito

Keyword(s):

Amyotrophic Lateral Sclerosis ◽

Motor Neuron ◽

P2x7 Receptor ◽

Extracellular Atp ◽

Neuron Death ◽

Motor Neuron Death ◽

Lateral Sclerosis

Download Full-text