Photolabeling reveals the proximity of the alpha-neurotoxin binding site to the M2 helix of the ion channel in the nicotinic acetylcholine receptor.

Identification of Amino Acids in the Nicotinic Acetylcholine Receptor Agonist Binding Site and Ion Channel Photolabeled by 4-[(3-Trifluoromethyl)-3H-Diazirin-3-yl]Benzoylcholine, a Novel Photoaffinity Antagonist†

Biochemistry ◽

10.1021/bi0269815 ◽

2003 ◽

Vol 42 (2) ◽

pp. 271-283 ◽

Cited By ~ 14

Author(s):

David C. Chiara ◽

Jonathan C. Trinidad ◽

Dong Wang ◽

Michael R. Ziebell ◽

Deirdre Sullivan ◽

...

Keyword(s):

Amino Acids ◽

Ion Channel ◽

Binding Site ◽

Acetylcholine Receptor ◽

Receptor Agonist ◽

Agonist Binding ◽

Examining the Noncompetitive Antagonist-binding Site in the Ion Channel of the Nicotinic Acetylcholine Receptor in the Resting State

10.1074/jbc.275.5.3469 ◽

2000 ◽

Vol 275 (5) ◽

pp. 3469-3478 ◽

Cited By ~ 14

Author(s):

Michael P. Blanton ◽

Elizabeth A. McCardy ◽

Martin J. Gallagher

Keyword(s):

Ion Channel ◽

Binding Site ◽

Acetylcholine Receptor ◽

Resting State ◽

Nicotinic Acetylcholine ◽

Antagonist Binding

Location of the Polyamine Binding Site in the Vestibule of the Nicotinic Acetylcholine Receptor Ion Channel

10.1074/jbc.m008467200 ◽

2000 ◽

Vol 276 (9) ◽

pp. 6151-6160 ◽

Cited By ~ 22

Author(s):

M. Gabriele Bixel ◽

Christoph Weise ◽

Maria L. Bolognesi ◽

Michela Rosini ◽

Matthew J. Brierly ◽

...

Keyword(s):

Ion Channel ◽

Binding Site ◽

Acetylcholine Receptor ◽

Nicotinic Acetylcholine ◽

Polyamine Binding Site

The tethered agonist approach to mapping ion channel proteins – toward a structural model for the agonist binding site of the nicotinic acetylcholine receptor

Chemistry & Biology ◽

10.1016/s1074-5521(00)00055-7 ◽

2001 ◽

Vol 8 (1) ◽

pp. 47-58 ◽

Cited By ~ 22

Author(s):

Lintong Li ◽

Wenge Zhong ◽

Niki Zacharias ◽

Caroline Gibbs ◽

Henry A Lester ◽

...

Keyword(s):

Ion Channel ◽

Binding Site ◽

Acetylcholine Receptor ◽

Structural Model ◽

Agonist Binding ◽

Nicotinic Acetylcholine ◽

Channel Proteins ◽

Ion Channel Proteins

Architecture of the Neuronal Nicotinic Acetylcholine Receptor Ion Channel at the Binding Site of bis-Ammonium Blockers

The Journal of Membrane Biology ◽

10.1007/s002329900087 ◽

1996 ◽

Vol 152 (1) ◽

pp. 77-87 ◽

Cited By ~ 9

Author(s):

N.B. Brovtsyna ◽

D.B. Tikhonov ◽

O.B. Gorbunova ◽

V.E. Gmiro ◽

S.E. Serduk ◽

...

Keyword(s):

Ion Channel ◽

Binding Site ◽

Acetylcholine Receptor ◽

Neuronal Nicotinic Acetylcholine Receptor ◽

Structure of the agonist-binding site of the nicotinic acetylcholine receptor. [3H]acetylcholine mustard identifies residues in the cation-binding subsite.

10.1016/s0021-9258(18)54504-x ◽

1991 ◽

Vol 266 (34) ◽

pp. 23354-23364

Author(s):

J.B. Cohen ◽

S.D. Sharp ◽

W.S. Liu

Keyword(s):

Binding Site ◽

Acetylcholine Receptor ◽

Cation Binding ◽

Agonist Binding ◽

Expression of the alpha-bungarotoxin binding site of the nicotinic acetylcholine receptor by Escherichia coli transformants.

Proceedings of the National Academy of Sciences ◽

10.1073/pnas.84.12.4318 ◽

1987 ◽

Vol 84 (12) ◽

pp. 4318-4321 ◽

Cited By ~ 44

Author(s):

J. M. Gershoni

Keyword(s):

Escherichia Coli ◽

Binding Site ◽

Acetylcholine Receptor ◽

Nicotinic Acetylcholine ◽

Alpha Bungarotoxin

Probing the Agonist Domain of the Nicotinic Acetylcholine Receptor by Cysteine Scanning Mutagenesis Reveals Residues in Proximity to the α-Bungarotoxin Binding Site†

Biochemistry ◽

10.1021/bi982656z ◽

1999 ◽

Vol 38 (16) ◽

pp. 4912-4921 ◽

Cited By ~ 18

Author(s):

Armin Spura ◽

Tanya S. Russin ◽

Neal D. Freedman ◽

Marianne Grant ◽

James T. McLaughlin ◽

...

Keyword(s):

Binding Site ◽

Acetylcholine Receptor ◽

Nicotinic Acetylcholine ◽

Cysteine Scanning ◽

Cysteine Scanning Mutagenesis

An allosteric binding site of the α7 nicotinic acetylcholine receptor revealed in a humanized acetylcholine-binding protein

10.1074/jbc.m117.815316 ◽

2017 ◽

Vol 293 (7) ◽

pp. 2534-2545 ◽

Cited By ~ 15

Author(s):

Florian Delbart ◽

Marijke Brams ◽

Fabian Gruss ◽

Sam Noppen ◽

Steve Peigneur ◽

...

Keyword(s):

Binding Site ◽

Acetylcholine Receptor ◽

Binding Protein ◽

Α7 Nicotinic Acetylcholine Receptor ◽

Nicotinic Acetylcholine ◽

Acetylcholine Binding Protein

A Transmembrane Binding Site at a Subunit Interface for Torpedo Nicotinic Acetylcholine Receptor Potentiators And Inhibitors

Biophysical Journal ◽

10.1016/j.bpj.2009.12.708 ◽

2010 ◽

Vol 98 (3) ◽

pp. 131a

Author(s):

Ayman K. Hamouda ◽

Deidre Stewart ◽

S. Shaukat Husain ◽

Jonathan B. Cohen

Keyword(s):

Binding Site ◽

Acetylcholine Receptor ◽

Nicotinic Acetylcholine ◽

Subunit Interface ◽

A Subunit