scholarly journals Activity-dependent Release of Brain-derived Neurotrophic Factor Underlies the Neuroprotective Effect ofN-Methyl-d-aspartate

1998 ◽  
Vol 273 (45) ◽  
pp. 29394-29399 ◽  
Author(s):  
Ann M. Marini ◽  
Stuart J. Rabin ◽  
Robert H. Lipsky ◽  
Italo Mocchetti
Keyword(s):  
Neurotrophic Factor ◽  
Neuroprotective Effect ◽  
Brain Derived Neurotrophic Factor ◽  
Activity Dependent

Brain-Derived Neurotrophic Factor Systemic Response in the Periodontium, Trigeminal Nucleus Caudalis, and Hippocampus Induced by Occlusal Trauma

2021 ◽  
Vol 17 (7) ◽  
pp. 1371-1379
Author(s):  
Di Liu ◽  
Ying Li ◽  
Jiechen Liu ◽  
Zhiyuan Shen ◽  
Fengying Wang ◽  
...  
Keyword(s):  
Neurotrophic Factor ◽  
Brain Derived Neurotrophic Factor ◽  
Systemic Response ◽  
Periodontal Tissue ◽  
Trigeminal Nucleus ◽  
Bdnf Gene ◽  
Dental Tissue ◽  
Injury And Repair ◽  
Activity Dependent ◽  
The Brain

Occlusal trauma (OT), by causing periodontal tissue damage, can activate and enhance the activity of the peripheral and central nervous system (CNS) neuropeptides. The brain-derived neurotrophic factor (BDNF) gene is activity-dependent and exhibits marked alterations, characterized by protection against injury and repair. Our results show the possible molecular mechanism through which noxious environmental stimuli induce alterations in BDNF activity in the local periodontal tissue, the primary sensory neurons-Vc, and the hippocampus, suggesting systemic impairment. BDNF serves a more positive and enduring trauma protection and repair function in Vc compared to that in local dental tissue.

scholarly journals Brain-Derived Neurotrophic Factor Mediates the Activity-Dependent Regulation of Inhibition in Neocortical Cultures

1997 ◽  
Vol 17 (12) ◽  
pp. 4527-4535 ◽  
Author(s):  
Lana C. Rutherford ◽  
Andrew DeWan ◽  
Holly M. Lauer ◽  
Gina G. Turrigiano
Keyword(s):  
Neurotrophic Factor ◽  
Brain Derived Neurotrophic Factor ◽  
Activity Dependent

Possible involvement of induction of brain-derived neurotrophic factor in the neuroprotective effect of a 5-phenylpyrimidine derivative

2003 ◽  
Vol 66 (6) ◽  
pp. 1019-1023 ◽  
Author(s):  
Kayo Matsumoto ◽  
Kyoko Yamamoto ◽  
Yasuko Karasawa ◽  
Noriko Hino ◽  
Atsushi Nakamura ◽  
...  
Keyword(s):  
Neurotrophic Factor ◽  
Neuroprotective Effect ◽  
Brain Derived Neurotrophic Factor

scholarly journals Differential Activity-Dependent Secretion of Brain-Derived Neurotrophic Factor from Axon and Dendrite

2009 ◽  
Vol 29 (45) ◽  
pp. 14185-14198 ◽  
Author(s):  
N. Matsuda ◽  
H. Lu ◽  
Y. Fukata ◽  
J. Noritake ◽  
H. Gao ◽  
...  
Keyword(s):  
Neurotrophic Factor ◽  
Brain Derived Neurotrophic Factor ◽  
Activity Dependent
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