Spinocerebellar Ataxia Type 6 Mutation Alters P-type Calcium Channel Function

Journal of Biological Chemistry ◽

10.1074/jbc.275.15.10893 ◽

2000 ◽

Vol 275 (15) ◽

pp. 10893-10898 ◽

Author(s):

Shuta Toru ◽

Takayuki Murakoshi ◽

Kinya Ishikawa ◽

Hironao Saegusa ◽

Hiroto Fujigasaki ◽

...

Keyword(s):

Calcium Channel ◽

Spinocerebellar Ataxia ◽

Spinocerebellar Ataxia Type ◽

Channel Function ◽

Spinocerebellar Ataxia Type 6 ◽

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Faculty Opinions recommendation of Proteolytic cleavage and cellular toxicity of the human alpha1A calcium channel in spinocerebellar ataxia type 6.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1013854.191971 ◽

2003 ◽

Author(s):

Annette Dolphin

Keyword(s):

Calcium Channel ◽

Spinocerebellar Ataxia ◽

Proteolytic Cleavage ◽

Spinocerebellar Ataxia Type ◽

Cellular Toxicity ◽

Spinocerebellar Ataxia Type 6

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The P/Q-type voltage-dependent calcium channel as pharmacological target in spinocerebellar ataxia type 6: Gabapentin and pregabalin may be of therapeutic benefit

Medical Hypotheses ◽

10.1016/j.mehy.2006.06.014 ◽

2007 ◽

Vol 68 (1) ◽

pp. 131-136 ◽

Author(s):

José Gazulla ◽

Marı´a Tintoré

Keyword(s):

Calcium Channel ◽

Spinocerebellar Ataxia ◽

Therapeutic Benefit ◽

Spinocerebellar Ataxia Type ◽

Voltage Dependent Calcium Channel ◽

Spinocerebellar Ataxia Type 6 ◽

Voltage Dependent ◽

Pharmacological Target

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Abundant expression and cytoplasmic aggregations of alpha1A voltage-dependent calcium channel protein associated with neurodegeneration in spinocerebellar ataxia type 6

Human Molecular Genetics ◽

10.1093/hmg/8.7.1185 ◽

1999 ◽

Vol 8 (7) ◽

pp. 1185-1193 ◽

Author(s):

K. Ishikawa

Keyword(s):

Calcium Channel ◽

Spinocerebellar Ataxia ◽

Spinocerebellar Ataxia Type ◽

Channel Protein ◽

Voltage Dependent Calcium Channel ◽

Spinocerebellar Ataxia Type 6 ◽

Voltage Dependent

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The carboxy-terminal fragment of α1A calcium channel preferentially aggregates in the cytoplasm of human spinocerebellar ataxia type 6 Purkinje cells

Acta Neuropathologica ◽

10.1007/s00401-009-0630-0 ◽

2009 ◽

Vol 119 (4) ◽

pp. 447-464 ◽

Author(s):

Taro Ishiguro ◽

Kinya Ishikawa ◽

Makoto Takahashi ◽

Masato Obayashi ◽

Takeshi Amino ◽

...

Keyword(s):

Calcium Channel ◽

Purkinje Cells ◽

Spinocerebellar Ataxia ◽

Spinocerebellar Ataxia Type ◽

Spinocerebellar Ataxia Type 6 ◽

Terminal Fragment ◽

Carboxy Terminal

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The P/Q-type voltage-dependent calcium channel: a therapeutic target in spinocerebellar ataxia type 6

Acta Neurologica Scandinavica ◽

10.1111/j.1600-0404.2006.00752.x ◽

2007 ◽

Vol 115 (5) ◽

pp. 356-363 ◽

Author(s):

J. Gazulla ◽

M. Tintoré

Keyword(s):

Calcium Channel ◽

Spinocerebellar Ataxia ◽

Therapeutic Target ◽

Spinocerebellar Ataxia Type ◽

Voltage Dependent Calcium Channel ◽

Spinocerebellar Ataxia Type 6 ◽

Voltage Dependent

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EXPRESSION OF ALPHA IA-VOLTAGE-DEPENDENT CALCIUM CHANNEL MESSENGER RNA/PROTEIN IN BRAINS OF SPINOCEREBELLAR ATAXIA TYPE 6 (SCA6)

Journal of Neuropathology & Experimental Neurology ◽

10.1097/00005072-199905000-00171 ◽

1999 ◽

Vol 58 (5) ◽

pp. 549

Author(s):

K. Ishikawa ◽

H. Fujigasaki ◽

H. Saegusa ◽

N. Ohkoshi ◽

S. Shoji ◽

...

Keyword(s):

Calcium Channel ◽

Spinocerebellar Ataxia ◽

Messenger Rna ◽

Spinocerebellar Ataxia Type ◽

Voltage Dependent Calcium Channel ◽

Spinocerebellar Ataxia Type 6 ◽

Voltage Dependent

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Spinocerebellar Ataxia Type 6: Molecular Mechanisms and Calcium Channel Genetics

Polyglutamine Disorders - Advances in Experimental Medicine and Biology ◽

10.1007/978-3-319-71779-1_7 ◽

2018 ◽

pp. 147-173 ◽

Author(s):

Xiaofei Du ◽

Christopher Manuel Gomez

Keyword(s):

Calcium Channel ◽

Spinocerebellar Ataxia ◽

Molecular Mechanisms ◽

Spinocerebellar Ataxia Type ◽

Spinocerebellar Ataxia Type 6

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Erratum to: Spinocerebellar Ataxia Type 6: Molecular Mechanisms and Calcium Channel Genetics

Polyglutamine Disorders - Advances in Experimental Medicine and Biology ◽

10.1007/978-3-319-71779-1_22 ◽

2018 ◽

pp. E1-E1

Author(s):

Xiaofei Du ◽

Christopher Manuel Gomez

Keyword(s):

Calcium Channel ◽

Spinocerebellar Ataxia ◽

Molecular Mechanisms ◽

Spinocerebellar Ataxia Type ◽

Spinocerebellar Ataxia Type 6

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Proteolytic cleavage and cellular toxicity of the human α1A calcium channel in spinocerebellar ataxia type 6

Neuroscience Letters ◽

10.1016/s0304-3940(03)00156-3 ◽

2003 ◽

Vol 341 (1) ◽

pp. 74-78 ◽

Author(s):

Takayuki Kubodera ◽

Takanori Yokota ◽

Kiyoshi Ohwada ◽

Kinya Ishikawa ◽

Hiroyuki Miura ◽

...

Keyword(s):

Calcium Channel ◽

Spinocerebellar Ataxia ◽

Proteolytic Cleavage ◽

Spinocerebellar Ataxia Type ◽

Cellular Toxicity ◽

Spinocerebellar Ataxia Type 6

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Frequency analysis of autosomal dominant cerebellar ataxias in Japanese patients and clinical characterization of spinocerebellar ataxia type 6

Clinical Genetics ◽

10.1034/j.1399-0004.1998.531530104.x ◽

1998 ◽

Vol 53 (1) ◽

pp. 13-19 ◽

Author(s):

Hidetaka Watanabe ◽

Fumiaki Tanaka ◽

Michiyo Matsumoto ◽

Manabu Doyu ◽

Tetsuo Ando ◽

...

Keyword(s):

Spinocerebellar Ataxia ◽

Frequency Analysis ◽

Autosomal Dominant ◽

Japanese Patients ◽

Spinocerebellar Ataxia Type ◽

Spinocerebellar Ataxia Type 6 ◽

Cerebellar Ataxias

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