scholarly journals Substrate recognition by the Cdh1 destruction box receptor is a general requirement for APC/CCdh1-mediated proteolysis.

2017 ◽  
Vol 292 (12) ◽  
pp. 5125-5127
Author(s):  
Liang Qin ◽  
Dimitrius Santiago P. S. F. Guimarães ◽  
Michael Melesse ◽  
Mark C. Hall
Keyword(s):  
Substrate Recognition ◽  
General Requirement ◽  
Destruction Box

scholarly journals Substrate Recognition by the Cdh1 Destruction Box Receptor Is a General Requirement for APC/CCdh1-mediated Proteolysis

2016 ◽  
Vol 291 (30) ◽  
pp. 15564-15574 ◽  
Author(s):  
Liang Qin ◽  
Dimitrius Santiago P. S. F. Guimarães ◽  
Michael Melesse ◽  
Mark C. Hall
Keyword(s):  
Substrate Recognition ◽  
General Requirement ◽  
Destruction Box

Substrate Recognition by Vitamin K-Dependent Carboxylase

1987 ◽  
Vol 57 (01) ◽  
pp. 017-019 ◽  
Author(s):  
Magda M W Ulrich ◽  
Berry A M Soute ◽  
L Johan M van Haarlem ◽  
Cees Vermeer
Keyword(s):  
Amino Acid ◽  
Vitamin K ◽  
Substrate Recognition ◽  
Bovine Liver ◽  
Amino Acid Residues

SummaryDecarboxylated osteocalcins were prepared and purified from bovine, chicken, human and monkey bones and assayed for their ability to serve as a substrate for vitamin K-dependent carboxylase from bovine liver. Substantial differences were observed, especially between bovine and monkey d-osteocalcin. Since these substrates differ only in their amino acid residues 3 and 4, it seems that these residues play a role in the recognition of a substrate by hepatic carboxylase.

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