destruction box
Recently Published Documents


TOTAL DOCUMENTS

47
(FIVE YEARS 0)

H-INDEX

21
(FIVE YEARS 0)

2017 ◽  
Vol 292 (12) ◽  
pp. 5125-5127
Author(s):  
Liang Qin ◽  
Dimitrius Santiago P. S. F. Guimarães ◽  
Michael Melesse ◽  
Mark C. Hall

2016 ◽  
Vol 43 (11) ◽  
pp. 1285-1292 ◽  
Author(s):  
Fei-Fei Huang ◽  
Ping-An Chang ◽  
Lan-Xi Sun ◽  
Wen-Zhen Qin ◽  
Li-Ping Han ◽  
...  
Keyword(s):  

2016 ◽  
Vol 291 (30) ◽  
pp. 15564-15574 ◽  
Author(s):  
Liang Qin ◽  
Dimitrius Santiago P. S. F. Guimarães ◽  
Michael Melesse ◽  
Mark C. Hall

2013 ◽  
Vol 2013 ◽  
pp. 1-8 ◽  
Author(s):  
Chao-Hsun Yang ◽  
Wan-Ting Kuo ◽  
Yun-Ting Chuang ◽  
Cheng-Yu Chen ◽  
Chih-Chien Lin

The periodic expression and destruction of several cyclins are the most important steps for the exact regulation of cell cycle. Cyclins are degraded by the ubiquitin-proteasome system during cell cycle. Besides, a short sequence near the N-terminal of cyclin B called the destruction box (D-box; CDB) is also required. Fluorescent-protein-based reporter gene system is insensitive to analysis because of the overly stable fluorescent proteins. Therefore, in this study, we use human CDB fused with both enhanced green fluorescent protein (EGFP) at C-terminus and red fluorescent protein (RFP, DsRed) at N-terminus in the transfected human melanoma cells to examine the effects of CDB on different fluorescent proteins. Our results indicated that CDB-fused fluorescent protein can be used to examine the slight gene regulations in the reporter gene system and have the potential to be the system for screening of functional compounds in the future.


Author(s):  
Thomas J. Lukas ◽  
Daniela V. Rosa ◽  
Luiz Alexandre V. Magno ◽  
Bruno R. Souza ◽  
Marco A. Romano-Silva ◽  
...  
Keyword(s):  

Sign in / Sign up

Export Citation Format

Share Document