scholarly journals Reciprocal Regulatory Interaction between Human Herpesvirus 8 and Human Immunodeficiency Virus Type 1

2001 ◽  
Vol 276 (16) ◽  
pp. 13427-13432 ◽  
Author(s):  
Li-Min Huang ◽  
Miao-Fen Chao ◽  
Mao-Yuan Chen ◽  
Hsiu-ming Shih ◽  
Yu-Ping Chiang ◽  
...  
Keyword(s):  
Human Immunodeficiency Virus ◽  
Human Immunodeficiency Virus Type ◽  
Virus Type ◽  
Human Herpesvirus ◽  
Human Herpesvirus 8 ◽  
Regulatory Interaction ◽  
Herpesvirus 8 ◽  
Immunodeficiency Virus

scholarly journals Searching for Human Herpesvirus 8 Antibodies in Serum Samples from Patients Infected with Human Immunodeficiency Virus Type 1 and Blood Donors from São Paulo, Brazil

1999 ◽  
Vol 179 (6) ◽  
pp. 1591-1592 ◽  
Author(s):  
Adele Caterino‐de‐Araujo ◽  
Maria Luisa Calabrò ◽  
Elizabeth de los Santos‐Fortuna ◽  
Jamal Suleiman ◽  
Luigi Chieco‐Bianchi
Keyword(s):  
Human Immunodeficiency Virus ◽  
Human Immunodeficiency Virus Type ◽  
Virus Type ◽  
Blood Donors ◽  
Human Herpesvirus ◽  
Human Herpesvirus 8 ◽  
Serum Samples ◽  
Herpesvirus 8 ◽  
Immunodeficiency Virus

scholarly journals Human herpesvirus-8 (Kaposi’s sarcoma-associated herpesvirus) ORF50 interacts synergistically with the tat gene product in transactivating the human immunodeficiency virus type 1 LTR

2001 ◽  
Vol 82 (8) ◽  
pp. 1965-1970 ◽  
Author(s):  
Elisabetta Caselli ◽  
Paola Menegazzi ◽  
Arianna Bracci ◽  
Monica Galvan ◽  
Enzo Cassai ◽  
...  
Keyword(s):  
Human Immunodeficiency Virus ◽  
Human Immunodeficiency Virus Type ◽  
Virus Type ◽  
Human Herpesvirus ◽  
Biologically Active ◽  
Human Herpesvirus 8 ◽  
Herpesvirus 8 ◽  
Immunodeficiency Virus ◽  
Hiv 1

Human herpesvirus-8 (HHV-8) is a lymphotropic virus associated with several AIDS-related neoplasms. Two ORFs play a critical role in the regulation of virus replication: ORF50, encoding an immediate-early transcriptional activator, and ORF57, encoding a post-transcriptional regulator. We analysed their effects on the activation of the human immunodeficiency virus type 1 (HIV-1) LTR. ORF50 interacted synergically with tat, inducing a 10-fold enhancement of HIV-1 LTR transactivation. This effect occurred both in BCBL-1 cells, latently infected with HHV-8, and in HL3T1 cells, an epithelial cell line non-permissive to HHV-8 infection. Also, ORF57 enhanced tat-induced transactivation of HIV-1 LTR, but only in BCBL-1 cells, suggesting that its action was likely mediated by the induction of other viral functions. Finally, when both ORFs were expressed, the enhancement of transactivation induced by ORF50 was partially inhibited. The findings suggest that ORF57 can modulate ORF50 activity and that ORF50 may render biologically active small amounts of tat.

scholarly journals Postnatal Human Herpesvirus 8 and Human Immunodeficiency Virus Type 1 Infection in Mothers and Infants from Zambia

2003 ◽  
Vol 187 (4) ◽  
pp. 559-568 ◽  
Author(s):  
Brad P. Brayfield ◽  
Saul Phiri ◽  
Chipepo Kankasa ◽  
Jubra Muyanga ◽  
Hamakwa Mantina ◽  
...  
Keyword(s):  
Human Immunodeficiency Virus ◽  
Human Immunodeficiency Virus Type ◽  
Virus Type ◽  
Human Herpesvirus ◽  
Human Herpesvirus 8 ◽  
Herpesvirus 8 ◽  
Immunodeficiency Virus
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