Metal Deficiency Increases Aberrant Hydrophobicity of Mutant Superoxide Dismutases That Cause Amyotrophic Lateral Sclerosis

Ashutosh Tiwari; Amir Liba; Se Hui Sohn; Sai V. Seetharaman; Osman Bilsel; C. Robert Matthews; P. John Hart; Joan Selverstone Valentine; Lawrence J. Hayward

doi:10.1074/jbc.m109.043729

Metal Deficiency Increases Aberrant Hydrophobicity of Mutant Superoxide Dismutases That Cause Amyotrophic Lateral Sclerosis

Journal of Biological Chemistry ◽

10.1074/jbc.m109.043729 ◽

2009 ◽

Vol 284 (40) ◽

pp. 27746-27758 ◽

Cited By ~ 43

Author(s):

Ashutosh Tiwari ◽

Amir Liba ◽

Se Hui Sohn ◽

Sai V. Seetharaman ◽

Osman Bilsel ◽

...

Keyword(s):

Amyotrophic Lateral Sclerosis ◽

Superoxide Dismutases ◽

Metal Deficiency ◽

Lateral Sclerosis

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Immunohistochemical Study on Superoxide Dismutases in Spinal Cords from Autopsied Patients with Amyotrophic Lateral Sclerosis

Developmental Neuroscience ◽

10.1159/000111445 ◽

1996 ◽

Vol 18 (5-6) ◽

pp. 492-498 ◽

Cited By ~ 77

Author(s):

Noriyuki Shibata ◽

Kohtaro Asayama ◽

Asao Hirano ◽

Makio Kobayashi

Keyword(s):

Amyotrophic Lateral Sclerosis ◽

Immunohistochemical Study ◽

Superoxide Dismutases ◽

Lateral Sclerosis

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Gain in functions of mutant Cu,Zn-superoxide dismutases as a causative factor in familial amyotrophic lateral sclerosis: Less reactive oxidant formation but high spontaneous aggregation and precipitation

Free Radical Research ◽

10.1080/10715760000300621 ◽

2000 ◽

Vol 33 (1) ◽

pp. 65-73 ◽

Cited By ~ 19

Author(s):

Ayako Okado-Matsumoto ◽

Theingi Myint ◽

Junichi Fujii ◽

Naoyuki Taniguchi

Keyword(s):

Amyotrophic Lateral Sclerosis ◽

Causative Factor ◽

Superoxide Dismutases ◽

Familial Amyotrophic Lateral Sclerosis ◽

Spontaneous Aggregation ◽

Reactive Oxidant ◽

Lateral Sclerosis

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Nonamyloid Aggregates Arising from Mature Copper/Zinc Superoxide Dismutases Resemble Those Observed in Amyotrophic Lateral Sclerosis

Journal of Biological Chemistry ◽

10.1074/jbc.m110.113696 ◽

2010 ◽

Vol 285 (53) ◽

pp. 41701-41711 ◽

Cited By ~ 39

Author(s):

Young-Mi Hwang ◽

Peter B. Stathopulos ◽

Kristin Dimmick ◽

Hong Yang ◽

Hamid R. Badiei ◽

...

Keyword(s):

Amyotrophic Lateral Sclerosis ◽

Superoxide Dismutases ◽

Copper Zinc ◽

Copper Zinc Superoxide Dismutases ◽

Lateral Sclerosis

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Loss of in Vitro Metal Ion Binding Specificity in Mutant Copper-Zinc Superoxide Dismutases Associated with Familial Amyotrophic Lateral Sclerosis

Journal of Biological Chemistry ◽

10.1074/jbc.275.2.1007 ◽

2000 ◽

Vol 275 (2) ◽

pp. 1007-1014 ◽

Cited By ~ 120

Author(s):

Joy J. Goto ◽

Haining Zhu ◽

Raylene J. Sanchez ◽

Aram Nersissian ◽

Edith Butler Gralla ◽

...

Keyword(s):

Amyotrophic Lateral Sclerosis ◽

Metal Ion ◽

Superoxide Dismutases ◽

Familial Amyotrophic Lateral Sclerosis ◽

Ion Binding ◽

Metal Ion Binding ◽

Copper Zinc ◽

Copper Zinc Superoxide Dismutases ◽

Lateral Sclerosis

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Effect of overexpression of wild-type and mutant Cu/Zn-superoxide dismutases on oxidative damage and antioxidant defences: relevance to Down's syndrome and familial amyotrophic lateral sclerosis

Journal of Neurochemistry ◽

10.1046/j.1471-4159.2001.00107.x ◽

2001 ◽

Vol 76 (4) ◽

pp. 957-965 ◽

Cited By ~ 56

Author(s):

MoonHee Lee ◽

Dong-Hoon Hyun ◽

Peter Jenner ◽

Barry Halliwell

Keyword(s):

Amyotrophic Lateral Sclerosis ◽

Oxidative Damage ◽

Down's Syndrome ◽

Down’S Syndrome ◽

Superoxide Dismutases ◽

Familial Amyotrophic Lateral Sclerosis ◽

Wild Type ◽

Antioxidant Defences ◽

Lateral Sclerosis

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Glycation proceeds faster in mutated Cu, Zn‐superoxide dismutases related to familial amyotrophic lateral sclerosis

The FASEB Journal ◽

10.1096/fj.02-0768fje ◽

2003 ◽

Vol 17 (8) ◽

pp. 1-18 ◽

Cited By ~ 25

Author(s):

Rina Takamiya ◽

Motoko Takahashi ◽

Theingi Myint ◽

Yong Seek Park ◽

Nobuko Miyazawa ◽

...

Keyword(s):

Amyotrophic Lateral Sclerosis ◽

Superoxide Dismutases ◽

Familial Amyotrophic Lateral Sclerosis ◽

Lateral Sclerosis

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Proteasomal Degradation of Mutant Superoxide Dismutases Linked to Amyotrophic Lateral Sclerosis

Journal of Biological Chemistry ◽

10.1074/jbc.m506247200 ◽

2005 ◽

Vol 280 (48) ◽

pp. 39907-39913 ◽

Cited By ~ 38

Author(s):

Luca Di Noto ◽

Lisa J. Whitson ◽

Xiaohang Cao ◽

P. John Hart ◽

Rodney L. Levine

Keyword(s):

Amyotrophic Lateral Sclerosis ◽

Proteasomal Degradation ◽

Superoxide Dismutases ◽

Lateral Sclerosis

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Mutant Cu,Zn superoxide dismutases and familial amyotrophic lateral sclerosis: evaluation of oxidative hypotheses

Free Radical Biology and Medicine ◽

10.1016/s0891-5849(03)00153-9 ◽

2003 ◽

Vol 34 (11) ◽

pp. 1383-1389 ◽

Cited By ~ 52

Author(s):

Stefan I. Liochev ◽

Irwin Fridovich

Keyword(s):

Amyotrophic Lateral Sclerosis ◽

Superoxide Dismutases ◽

Familial Amyotrophic Lateral Sclerosis ◽

Lateral Sclerosis

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Characterization of Wild-Type and Amyotrophic Lateral Sclerosis-Related Mutant Cu,Zn-Superoxide Dismutases Overproduced in Baculovirus-Infected Insect Cells

Journal of Neurochemistry ◽

10.1046/j.1471-4159.1995.64041456.x ◽

2002 ◽

Vol 64 (4) ◽

pp. 1456-1461 ◽

Cited By ~ 25

Author(s):

Junichi Fujii ◽

Theingi Myint ◽

Han Geuk Seo ◽

Yoshiro Kayanoki ◽

Yoshitaka Ikeda ◽

...

Keyword(s):

Amyotrophic Lateral Sclerosis ◽

Insect Cells ◽

Superoxide Dismutases ◽

Wild Type ◽

Infected Insect ◽

Lateral Sclerosis

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Equilibrium Thermodynamic Analysis of Amyotrophic Lateral Sclerosis-Associated Mutant Apo Cu,Zn Superoxide Dismutases†,‡

Biochemistry ◽

10.1021/bi0600953 ◽

2006 ◽

Vol 45 (23) ◽

pp. 7366-7379 ◽

Cited By ~ 40

Author(s):

Kenrick A. Vassall ◽

Peter B. Stathopulos ◽

Jessica A. O. Rumfeldt ◽

James R. Lepock ◽

Elizabeth M. Meiering

Keyword(s):

Amyotrophic Lateral Sclerosis ◽

Thermodynamic Analysis ◽

Superoxide Dismutases ◽

Equilibrium Thermodynamic ◽

Lateral Sclerosis

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