Nonamyloid Aggregates Arising from Mature Copper/Zinc Superoxide Dismutases Resemble Those Observed in Amyotrophic Lateral Sclerosis

Young-Mi Hwang; Peter B. Stathopulos; Kristin Dimmick; Hong Yang; Hamid R. Badiei; Ming Sze Tong; Jessica A. O. Rumfeldt; Pu Chen; Vassili Karanassios; Elizabeth M. Meiering

doi:10.1074/jbc.m110.113696

Nonamyloid Aggregates Arising from Mature Copper/Zinc Superoxide Dismutases Resemble Those Observed in Amyotrophic Lateral Sclerosis

Journal of Biological Chemistry ◽

10.1074/jbc.m110.113696 ◽

2010 ◽

Vol 285 (53) ◽

pp. 41701-41711 ◽

Cited By ~ 39

Author(s):

Young-Mi Hwang ◽

Peter B. Stathopulos ◽

Kristin Dimmick ◽

Hong Yang ◽

Hamid R. Badiei ◽

...

Keyword(s):

Amyotrophic Lateral Sclerosis ◽

Superoxide Dismutases ◽

Copper Zinc ◽

Copper Zinc Superoxide Dismutases ◽

Lateral Sclerosis

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Loss of in Vitro Metal Ion Binding Specificity in Mutant Copper-Zinc Superoxide Dismutases Associated with Familial Amyotrophic Lateral Sclerosis

Journal of Biological Chemistry ◽

10.1074/jbc.275.2.1007 ◽

2000 ◽

Vol 275 (2) ◽

pp. 1007-1014 ◽

Cited By ~ 120

Author(s):

Joy J. Goto ◽

Haining Zhu ◽

Raylene J. Sanchez ◽

Aram Nersissian ◽

Edith Butler Gralla ◽

...

Keyword(s):

Amyotrophic Lateral Sclerosis ◽

Metal Ion ◽

Superoxide Dismutases ◽

Familial Amyotrophic Lateral Sclerosis ◽

Ion Binding ◽

Metal Ion Binding ◽

Copper Zinc ◽

Copper Zinc Superoxide Dismutases ◽

Lateral Sclerosis

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Insights into SOD1-linked amyotrophic lateral sclerosis from NMR studies of Ni2+- and other metal-ion-substituted wild-type copper–zinc superoxide dismutases

JBIC Journal of Biological Inorganic Chemistry ◽

10.1007/s00775-014-1126-5 ◽

2014 ◽

Vol 19 (4-5) ◽

pp. 647-657 ◽

Cited By ~ 6

Author(s):

Li-June Ming ◽

Joan Selverstone Valentine

Keyword(s):

Amyotrophic Lateral Sclerosis ◽

Metal Ion ◽

Superoxide Dismutases ◽

Wild Type ◽

Nmr Studies ◽

Copper Zinc ◽

Copper Zinc Superoxide Dismutases ◽

Lateral Sclerosis

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Reactions of Hydrogen Peroxide with Familial Amyotrophic Lateral Sclerosis Mutant Human Copper-Zinc Superoxide Dismutases Studied by Pulse Radiolysis

Journal of Biological Chemistry ◽

10.1074/jbc.273.46.30104 ◽

1998 ◽

Vol 273 (46) ◽

pp. 30104-30109 ◽

Cited By ~ 51

Author(s):

Joy J. Goto ◽

Edith Butler Gralla ◽

Joan Selverstone Valentine ◽

Diane E. Cabelli

Keyword(s):

Hydrogen Peroxide ◽

Amyotrophic Lateral Sclerosis ◽

Pulse Radiolysis ◽

Superoxide Dismutases ◽

Familial Amyotrophic Lateral Sclerosis ◽

Copper Zinc ◽

Copper Zinc Superoxide Dismutases ◽

Lateral Sclerosis

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Metal Deficiency Increases Aberrant Hydrophobicity of Mutant Superoxide Dismutases That Cause Amyotrophic Lateral Sclerosis

Journal of Biological Chemistry ◽

10.1074/jbc.m109.043729 ◽

2009 ◽

Vol 284 (40) ◽

pp. 27746-27758 ◽

Cited By ~ 43

Author(s):

Ashutosh Tiwari ◽

Amir Liba ◽

Se Hui Sohn ◽

Sai V. Seetharaman ◽

Osman Bilsel ◽

...

Keyword(s):

Amyotrophic Lateral Sclerosis ◽

Superoxide Dismutases ◽

Metal Deficiency ◽

Lateral Sclerosis

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Direct Probing of Copper Active Site and Free Radical Formed during Bicarbonate-dependent Peroxidase Activity of Bovine and Human Copper,Zinc-superoxide Dismutases

Journal of Biological Chemistry ◽

10.1074/jbc.m314272200 ◽

2004 ◽

Vol 279 (31) ◽

pp. 32534-32540 ◽

Cited By ~ 23

Author(s):

Chandran Karunakaran ◽

Hao Zhang ◽

John P. Crow ◽

William E. Antholine ◽

B. Kalyanaraman

Keyword(s):

Free Radical ◽

Peroxidase Activity ◽

Active Site ◽

Superoxide Dismutases ◽

Copper Zinc ◽

Copper Zinc Superoxide Dismutases

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Immunohistochemical Study on Superoxide Dismutases in Spinal Cords from Autopsied Patients with Amyotrophic Lateral Sclerosis

Developmental Neuroscience ◽

10.1159/000111445 ◽

1996 ◽

Vol 18 (5-6) ◽

pp. 492-498 ◽

Cited By ~ 77

Author(s):

Noriyuki Shibata ◽

Kohtaro Asayama ◽

Asao Hirano ◽

Makio Kobayashi

Keyword(s):

Amyotrophic Lateral Sclerosis ◽

Immunohistochemical Study ◽

Superoxide Dismutases ◽

Lateral Sclerosis

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Dysregulation of intracellular copper trafficking pathway in a mouse model of mutant copper/zinc superoxide dismutase-linked familial amyotrophic lateral sclerosis

Journal of Neurochemistry ◽

10.1111/j.1471-4159.2009.06310.x ◽

2009 ◽

Vol 111 (1) ◽

pp. 181-191 ◽

Cited By ~ 38

Author(s):

Eiichi Tokuda ◽

Eriko Okawa ◽

Shin-ichi Ono

Keyword(s):

Amyotrophic Lateral Sclerosis ◽

Superoxide Dismutase ◽

Familial Amyotrophic Lateral Sclerosis ◽

Copper Trafficking ◽

Copper Zinc Superoxide Dismutase ◽

Zinc Superoxide Dismutase ◽

Trafficking Pathway ◽

Copper Zinc ◽

Lateral Sclerosis ◽

Intracellular Copper

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Human Copper-Zinc Superoxide Dismutase and Familial Amyotrophic Lateral Sclerosis

Protein Misfolding, Aggregation, and Conformational Diseases - Protein Reviews ◽

10.1007/978-0-387-36534-3_16 ◽

2007 ◽

pp. 327-344 ◽

Cited By ~ 1

Author(s):

Ahmad Galaleldeen ◽

P. John Hart

Keyword(s):

Amyotrophic Lateral Sclerosis ◽

Superoxide Dismutase ◽

Familial Amyotrophic Lateral Sclerosis ◽

Copper Zinc Superoxide Dismutase ◽

Zinc Superoxide Dismutase ◽

Copper Zinc ◽

Lateral Sclerosis

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Gain in functions of mutant Cu,Zn-superoxide dismutases as a causative factor in familial amyotrophic lateral sclerosis: Less reactive oxidant formation but high spontaneous aggregation and precipitation

Free Radical Research ◽

10.1080/10715760000300621 ◽

2000 ◽

Vol 33 (1) ◽

pp. 65-73 ◽

Cited By ~ 19

Author(s):

Ayako Okado-Matsumoto ◽

Theingi Myint ◽

Junichi Fujii ◽

Naoyuki Taniguchi

Keyword(s):

Amyotrophic Lateral Sclerosis ◽

Causative Factor ◽

Superoxide Dismutases ◽

Familial Amyotrophic Lateral Sclerosis ◽

Spontaneous Aggregation ◽

Reactive Oxidant ◽

Lateral Sclerosis

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Neuroprotective effects of copper/zinc-dependent superoxide dismutase against a wide variety of death-inducing stimuli and proapoptotic effect of familial amyotrophic lateral sclerosis mutations

Molecular Brain Research ◽

10.1016/s0169-328x(02)00560-0 ◽

2002 ◽

Vol 109 (1-2) ◽

pp. 189-197 ◽

Cited By ~ 5

Author(s):

Yogesh Patel ◽

Yolanda Collaco Moraes ◽

David Latchman ◽

Robert Coffin ◽

Jacqueline de Belleroche

Keyword(s):

Amyotrophic Lateral Sclerosis ◽

Superoxide Dismutase ◽

Familial Amyotrophic Lateral Sclerosis ◽

Neuroprotective Effects ◽

Copper Zinc ◽

Lateral Sclerosis

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