Gain in functions of mutant Cu,Zn-superoxide dismutases as a causative factor in familial amyotrophic lateral sclerosis: Less reactive oxidant formation but high spontaneous aggregation and precipitation

Causative Factor ◽

Superoxide Dismutases ◽

Spontaneous Aggregation ◽

Reactive Oxidant ◽

Loss of in Vitro Metal Ion Binding Specificity in Mutant Copper-Zinc Superoxide Dismutases Associated with Familial Amyotrophic Lateral Sclerosis

10.1074/jbc.275.2.1007 ◽

2000 ◽

Vol 275 (2) ◽

pp. 1007-1014 ◽

Cited By ~ 120

Author(s):

Joy J. Goto ◽

Haining Zhu ◽

Raylene J. Sanchez ◽

Aram Nersissian ◽

Edith Butler Gralla ◽

...

Keyword(s):

Metal Ion ◽

Superoxide Dismutases ◽

Ion Binding ◽

Metal Ion Binding ◽

Copper Zinc ◽

Copper Zinc Superoxide Dismutases ◽

Effect of overexpression of wild-type and mutant Cu/Zn-superoxide dismutases on oxidative damage and antioxidant defences: relevance to Down's syndrome and familial amyotrophic lateral sclerosis

Journal of Neurochemistry ◽

10.1046/j.1471-4159.2001.00107.x ◽

2001 ◽

Vol 76 (4) ◽

pp. 957-965 ◽

Cited By ~ 56

Author(s):

MoonHee Lee ◽

Dong-Hoon Hyun ◽

Peter Jenner ◽

Barry Halliwell

Keyword(s):

Oxidative Damage ◽

Down's Syndrome ◽

Down’S Syndrome ◽

Superoxide Dismutases ◽

Wild Type ◽

Antioxidant Defences ◽

Glycation proceeds faster in mutated Cu, Zn‐superoxide dismutases related to familial amyotrophic lateral sclerosis

The FASEB Journal ◽

10.1096/fj.02-0768fje ◽

2003 ◽

Vol 17 (8) ◽

pp. 1-18 ◽

Cited By ~ 25

Author(s):

Rina Takamiya ◽

Motoko Takahashi ◽

Theingi Myint ◽

Yong Seek Park ◽

Nobuko Miyazawa ◽

...

Keyword(s):

Superoxide Dismutases ◽

Mutant Cu,Zn superoxide dismutases and familial amyotrophic lateral sclerosis: evaluation of oxidative hypotheses

Free Radical Biology and Medicine ◽

10.1016/s0891-5849(03)00153-9 ◽

2003 ◽

Vol 34 (11) ◽

pp. 1383-1389 ◽

Cited By ~ 52

Author(s):

Stefan I. Liochev ◽

Irwin Fridovich

Keyword(s):

Superoxide Dismutases ◽

Decreased Metallation and Activity in Subsets of Mutant Superoxide Dismutases Associated with Familial Amyotrophic Lateral Sclerosis

10.1074/jbc.m112087200 ◽

2002 ◽

Vol 277 (18) ◽

pp. 15923-15931 ◽

Cited By ~ 253

Author(s):

Lawrence J. Hayward ◽

Jorge A. Rodriguez ◽

Ji W. Kim ◽

Ashutosh Tiwari ◽

Joy J. Goto ◽

...

Keyword(s):

Superoxide Dismutases ◽

Reactions of Hydrogen Peroxide with Familial Amyotrophic Lateral Sclerosis Mutant Human Copper-Zinc Superoxide Dismutases Studied by Pulse Radiolysis

10.1074/jbc.273.46.30104 ◽

1998 ◽

Vol 273 (46) ◽

pp. 30104-30109 ◽

Cited By ~ 51

Author(s):

Joy J. Goto ◽

Edith Butler Gralla ◽

Joan Selverstone Valentine ◽

Diane E. Cabelli

Keyword(s):

Hydrogen Peroxide ◽

Pulse Radiolysis ◽

Superoxide Dismutases ◽

Copper Zinc ◽

Copper Zinc Superoxide Dismutases ◽

Transgenic mouse model for familial amyotrophic lateral sclerosis with superoxide dismutase-1 mutation

Neuropathology ◽

10.1046/j.1440-1789.2001.00361.x ◽

2001 ◽

Vol 21 (1) ◽

pp. 82-92 ◽

Cited By ~ 72

Author(s):

Noriyuki Shibata

Keyword(s):

Superoxide Dismutase ◽

Mouse Model ◽

Transgenic Mouse ◽

Transgenic Mouse Model ◽

Superoxide Dismutase 1 ◽

389. Engineered microRNAs Against a C9ORF72 Transgenic Mouse Model To Treat Human Familial Amyotrophic Lateral Sclerosis (FALS)

Molecular Therapy ◽

10.1016/s1525-0016(16)35402-8 ◽

2014 ◽

Vol 22 ◽

pp. S148

Keyword(s):

Mouse Model ◽

Transgenic Mouse ◽

Transgenic Mouse Model ◽

The densitometric physical fractionator for counting neuronal populations: application to a mouse model of familial amyotrophic lateral sclerosis

Journal of Neuroscience Methods ◽

10.1016/s0165-0270(03)00201-2 ◽

2003 ◽

Vol 129 (1) ◽

pp. 61-71 ◽

Cited By ~ 9

Author(s):

Giuseppe Luca Ciavarro ◽

Novella Calvaresi ◽

Andrea Botturi ◽

Caterina Bendotti ◽

Giuseppe Andreoni ◽

...

Keyword(s):

Mouse Model ◽

Neuronal Populations ◽

Metal Deficiency Increases Aberrant Hydrophobicity of Mutant Superoxide Dismutases That Cause Amyotrophic Lateral Sclerosis

10.1074/jbc.m109.043729 ◽

2009 ◽

Vol 284 (40) ◽

pp. 27746-27758 ◽

Cited By ~ 43

Author(s):

Ashutosh Tiwari ◽

Amir Liba ◽

Se Hui Sohn ◽

Sai V. Seetharaman ◽

Osman Bilsel ◽

...

Keyword(s):

Superoxide Dismutases ◽

Metal Deficiency ◽