Discovery of a Novel Mode of Protein Kinase Inhibition Characterized by the Mechanism of Inhibition of Human Mesenchymal-epithelial Transition Factor (c-Met) Protein Autophosphorylation by ARQ 197

Factor C ◽

Erratum to “Discovery and optimization of a series of imidazo[4,5-b]pyrazine derivatives as highly potent and exquisitely selective inhibitors of the mesenchymal–epithelial transition factor (c-Met) protein kinase” [Bioorg. Med. Chem. 24 (2016) 4281–4290]

Bioorganic & Medicinal Chemistry ◽

10.1016/j.bmc.2017.03.042 ◽

2017 ◽

Vol 25 (10) ◽

pp. 2811-2812

Author(s):

Fei Zhao ◽

Jing Zhang ◽

Leduo Zhang ◽

Yu Hao ◽

Chen Shi ◽

...

Keyword(s):

Protein Kinase ◽

Selective Inhibitors ◽

Factor C ◽

Discovery of a Novel Class of Exquisitely Selective Mesenchymal-Epithelial Transition Factor (c-MET) Protein Kinase Inhibitors and Identification of the Clinical Candidate 2-(4-(1-(Quinolin-6-ylmethyl)-1H-[1,2,3]triazolo[4,5-b]pyrazin-6-yl)-1H-pyrazol-1-yl)ethanol (PF-04217903) for the Treatment of Cancer

Journal of Medicinal Chemistry ◽

10.1021/jm300967g ◽

2012 ◽

Vol 55 (18) ◽

pp. 8091-8109 ◽

Cited By ~ 64

Author(s):

J. Jean Cui ◽

Michele McTigue ◽

Mitchell Nambu ◽

Michelle Tran-Dubé ◽

Mason Pairish ◽

...

Keyword(s):

Protein Kinase ◽

Kinase Inhibitors ◽

Protein Kinase Inhibitors ◽

Factor C ◽

Mesenchymal Epithelial Transition ◽

Clinical Candidate

Discovery and optimization of a series of imidazo[4,5-b]pyrazine derivatives as highly potent and exquisitely selective inhibitors of the mesenchymal–epithelial transition factor (c-Met) protein kinase

Bioorganic & Medicinal Chemistry ◽

10.1016/j.bmc.2016.07.019 ◽

2016 ◽

Vol 24 (18) ◽

pp. 4281-4290 ◽

Cited By ~ 10

Author(s):

Fei Zhao ◽

Jing Zhang ◽

Leduo Zhang ◽

Yu Hao ◽

Chen Shi ◽

...

Keyword(s):

Protein Kinase ◽

Selective Inhibitors ◽

Factor C ◽

Faculty Opinions recommendation of Discovery of a novel class of exquisitely selective mesenchymal-epithelial transition factor (c-MET) protein kinase inhibitors and identification of the clinical candidate 2-(4-(1-(quinolin-6-ylmethyl)-1H-[1,2,3]triazolo[4,5-b]pyrazin-6-yl)-1H-pyrazol-1-yl)ethanol (PF-04217903) for the treatment of cancer.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.717967633.793467413 ◽

2012 ◽

Author(s):

Donald Pinto

Keyword(s):

Protein Kinase ◽

Kinase Inhibitors ◽

Protein Kinase Inhibitors ◽

Factor C ◽

Mesenchymal Epithelial Transition ◽

Clinical Candidate

Correction to Discovery of a Novel Class of Exquisitely Selective Mesenchymal-Epithelial Transition Factor (c-MET) Protein Kinase Inhibitors and Identification of the Clinical Candidate 2-(4-(1-(Quinolin-6-ylmethyl)-1H-[1,2,3]triazolo[4,5-b]pyrazin-6-yl)-1H-pyrazol-1-yl)ethanol (PF-04217903) for the Treatment of Cancer

Journal of Medicinal Chemistry ◽

10.1021/jm3014647 ◽

2012 ◽

Vol 55 (22) ◽

pp. 10314-10314 ◽

Cited By ~ 2

Author(s):

J. Jean Cui ◽

Michele McTigue ◽

Mitchell Nambu ◽

Michelle Tran-Dubé ◽

Mason Pairish ◽

...

Keyword(s):

Protein Kinase ◽

Kinase Inhibitors ◽

Protein Kinase Inhibitors ◽

Factor C ◽

Mesenchymal Epithelial Transition ◽

Clinical Candidate

Faculty Opinions recommendation of Structure based drug design of crizotinib (PF-02341066), a potent and selective dual inhibitor of mesenchymal-epithelial transition factor (c-MET) kinase and anaplastic lymphoma kinase (ALK).

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.12934957.14822055 ◽

2012 ◽

Author(s):

John Proudfoot

Keyword(s):

Drug Design ◽

Anaplastic Lymphoma Kinase ◽

Dual Inhibitor ◽

Structure Based Drug Design ◽

Anaplastic Lymphoma ◽

Factor C ◽

Faculty Opinions recommendation of Structure based drug design of crizotinib (PF-02341066), a potent and selective dual inhibitor of mesenchymal-epithelial transition factor (c-MET) kinase and anaplastic lymphoma kinase (ALK).

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.12934957.14323054 ◽

2011 ◽

Author(s):

John Lowe

Keyword(s):

Drug Design ◽

Anaplastic Lymphoma Kinase ◽

Dual Inhibitor ◽

Structure Based Drug Design ◽

Anaplastic Lymphoma ◽

Factor C ◽

Protein Kinase Inhibition in G2 Causes Mammalian Mcm Proteins to Reassociate with Chromatin and Restores Ability to Replicate

Experimental Cell Research ◽

10.1006/excr.1997.3829 ◽

1998 ◽

Vol 238 (1) ◽

pp. 63-69 ◽

Cited By ~ 19

Author(s):

Dawn Coverley ◽

Hannah R. Wilkinson ◽

Mark A. Madine ◽

Anthony D. Mills ◽

Ronald A. Laskey

Keyword(s):

Protein Kinase ◽

Kinase Inhibition ◽

Protein Kinase Inhibition ◽

Mcm Proteins

Phenolic compounds and their anti-oxidative properties and protein kinase inhibition from the Chinese mangrove plant Laguncularia racemosa

Phytochemistry ◽

10.1016/j.phytochem.2009.11.008 ◽

2010 ◽

Vol 71 (4) ◽

pp. 435-442 ◽

Cited By ~ 33

Author(s):

Cui Shi ◽

Min-Juan Xu ◽

Mirko Bayer ◽

Zhi-Wei Deng ◽

Michael H.G. Kubbutat ◽

...

Keyword(s):

Phenolic Compounds ◽

Protein Kinase ◽

Laguncularia Racemosa ◽

Mangrove Plant ◽

Kinase Inhibition ◽

Protein Kinase Inhibition

Challenging human somatic testicular cell reassembly by protein kinase inhibition –setting up a functional in vitro test system

Scientific Reports ◽

10.1038/s41598-020-65924-y ◽

2020 ◽

Vol 10 (1) ◽

Author(s):

M. Mincheva ◽

J. Wistuba ◽

C. Brenker ◽

S. Schlatt

Keyword(s):

Protein Kinase ◽

Test System ◽

In Vitro Test ◽

Testicular Cell ◽

Kinase Inhibition ◽

Protein Kinase Inhibition ◽

Vitro Test