scholarly journals Structural Basis of Leukotriene B412-Hydroxydehydrogenase/15-Oxo-prostaglandin 13-Reductase Catalytic Mechanism and a Possible Src Homology 3 Domain Binding Loop

2004 ◽  
Vol 279 (21) ◽  
pp. 22615-22623 ◽  
Author(s):  
Tetsuya Hori ◽  
Takehiko Yokomizo ◽  
Hideo Ago ◽  
Mitsuaki Sugahara ◽  
Go Ueno ◽  
...  
Keyword(s):  
Catalytic Mechanism ◽  
Structural Basis ◽  
Src Homology 3 ◽  
Src Homology 3 Domain ◽  
Src Homology ◽  
Binding Loop

Structural Basis of the Recognition of the SAMP Motif of Adenomatous Polyposis Coli by the Src-Homology 3 Domain

Biochemistry ◽  
2010 ◽  
Vol 49 (25) ◽  
pp. 5143-5153 ◽  
Author(s):  
Shuji Kaieda ◽  
Chiyuki Matsui ◽  
Yuko Mimori-Kiyosue ◽  
Takahisa Ikegami
Keyword(s):  
Adenomatous Polyposis Coli ◽  
Structural Basis ◽  
Adenomatous Polyposis ◽  
Polyposis Coli ◽  
Src Homology 3 ◽  
Src Homology 3 Domain ◽  
Src Homology

scholarly journals Structural Basis of Robo Proline-rich Motif Recognition by the srGAP1 Src Homology 3 Domain in the Slit-Robo Signaling Pathway

2006 ◽  
Vol 281 (38) ◽  
pp. 28430-28437 ◽  
Author(s):  
Xiaofeng Li ◽  
Yushu Chen ◽  
Yiwei Liu ◽  
Jia Gao ◽  
Feng Gao ◽  
...  
Keyword(s):  
Signaling Pathway ◽  
Structural Basis ◽  
Src Homology 3 ◽  
Src Homology 3 Domain ◽  
Src Homology ◽  
Motif Recognition

scholarly journals Myosin 1E coordinates actin assembly and cargo trafficking during clathrin-mediated endocytosis

2012 ◽  
Vol 23 (15) ◽  
pp. 2891-2904 ◽  
Author(s):  
Jackie Cheng ◽  
Alexandre Grassart ◽  
David G. Drubin
Keyword(s):  
Mammalian Cells ◽  
Actin Polymerization ◽  
Type I ◽  
Actin Assembly ◽  
Significant Delay ◽  
Src Homology 3 ◽  
Integral Role ◽  
Src Homology 3 Domain ◽  
Src Homology ◽  
Endocytic Vesicles

Myosin 1E (Myo1E) is recruited to sites of clathrin-mediated endocytosis coincident with a burst of actin assembly. The recruitment dynamics and lifetime of Myo1E are similar to those of tagged actin polymerization regulatory proteins. Like inhibition of actin assembly, depletion of Myo1E causes reduced transferrin endocytosis and a significant delay in transferrin trafficking to perinuclear compartments, demonstrating an integral role for Myo1E in these actin-mediated steps. Mistargeting of GFP-Myo1E or its src-homology 3 domain to mitochondria results in appearance of WIP, WIRE, N-WASP, and actin filaments at the mitochondria, providing evidence for Myo1E's role in actin assembly regulation. These results suggest for mammalian cells, similar to budding yeast, interdependence in the recruitment of type I myosins, WIP/WIRE, and N-WASP to endocytic sites for Arp2/3 complex activation to assemble F-actin as endocytic vesicles are being formed.

scholarly journals Blockade of v-Src-stimulated tumor formation by the Src homology 3 domain of Crk-associated substrate (Cas)

FEBS Letters ◽  
2003 ◽  
Vol 557 (1-3) ◽  
pp. 221-227 ◽  
Author(s):  
Chi-Hung Cheng ◽  
Kuo-Ching Yu ◽  
Hsin-Ling Chen ◽  
Shu-Yi Chen ◽  
Chi-Hui Huang ◽  
...  
Keyword(s):  
Tumor Formation ◽  
Src Homology 3 ◽  
Src Homology 3 Domain ◽  
Src Homology

scholarly journals An Src Homology 3 Domain-Like Fold Protein Forms a Ferredoxin Binding Site for the Chloroplast NADH Dehydrogenase-Like Complex in Arabidopsis

2011 ◽  
Vol 23 (4) ◽  
pp. 1480-1493 ◽  
Author(s):  
Hiroshi Yamamoto ◽  
Lianwei Peng ◽  
Yoichiro Fukao ◽  
Toshiharu Shikanai
Keyword(s):  
Binding Site ◽  
Nadh Dehydrogenase ◽  
Src Homology 3 ◽  
Src Homology 3 Domain ◽  
Src Homology
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