Transforming Growth Factor-β Receptor Type I-dependent Fibrogenic Gene Program Is Mediated via Activation of Smad1 and ERK1/2 Pathways

Receptor Type ◽

Type I ◽

Repression of transforming growth factor-β receptor type I promoter expression by Sp1 deficiency

Oncogene ◽

10.1038/sj.onc.1203822 ◽

2000 ◽

Vol 19 (40) ◽

pp. 4660-4667 ◽

Cited By ~ 18

Author(s):

Sumudra Periyasamy ◽

Sudhakar Ammanamanchi ◽

Manoranjani PM Tillekeratne ◽

Michael G Brattain

Keyword(s):

Growth Factor ◽

Receptor Type ◽

Type I ◽

Transforming Growth Factor β Receptor Type I Inhibitor, Galunisertib, Has No Beneficial Effects on Aneurysmal Pathological Changes in Marfan Mice

Biomolecules & Therapeutics ◽

10.4062/biomolther.2019.042 ◽

2020 ◽

Vol 28 (1) ◽

pp. 98-103

Author(s):

Jeong-Ho Park ◽

Min-Seob Kim ◽

Seokran Ham ◽

Eon Sub Park ◽

Koung Li Kim ◽

...

Keyword(s):

Growth Factor ◽

Receptor Type ◽

Type I ◽

Pathological Changes ◽

Beneficial Effects ◽

Transforming Growth Factor-β Receptor Type I and Type II Expression During Murine Hair Follicle Development and Cycling

Journal of Investigative Dermatology ◽

10.1111/1523-1747.ep12336635 ◽

1997 ◽

Vol 109 (4) ◽

pp. 518-526 ◽

Cited By ~ 86

Author(s):

Ralf Paus ◽

Kerstin Foitzik ◽

Pia Welker ◽

Silvia Bulfone-Paus ◽

Stefan Eichmüller

Keyword(s):

Growth Factor ◽

Hair Follicle ◽

Receptor Type ◽

Type I ◽

Follicle Development ◽

Type Ii ◽

Hair Follicle Development ◽

Optimization of a Dihydropyrrolopyrazole Series of Transforming Growth Factor-β Type I Receptor Kinase Domain Inhibitors: Discovery of an Orally Bioavailable Transforming Growth Factor-β Receptor Type I Inhibitor as Antitumor Agent

Journal of Medicinal Chemistry ◽

10.1021/jm701199p ◽

2008 ◽

Vol 51 (7) ◽

pp. 2302-2306 ◽

Cited By ~ 36

Author(s):

Hong-yu Li ◽

William T. McMillen ◽

Charles R. Heap ◽

Denis J. McCann ◽

Lei Yan ◽

...

Keyword(s):

Growth Factor ◽

Antitumor Agent ◽

Kinase Domain ◽

Receptor Type ◽

Type I ◽

Receptor Kinase ◽

Orally Bioavailable ◽

Regulation of Transforming Growth Factor-β-Receptor Type I and Type II Messenger Ribonucleic Acid Expression in the Hamster Ovary by Gonadotropinsand Steroid Hormones1

Biology of Reproduction ◽

10.1095/biolreprod62.6.1858 ◽

2000 ◽

Vol 62 (6) ◽

pp. 1858-1865 ◽

Cited By ~ 23

Author(s):

Shyamal K. Roy

Keyword(s):

Growth Factor ◽

Ribonucleic Acid ◽

Receptor Type ◽

Type I ◽

Type Ii ◽

Messenger Ribonucleic Acid ◽

Contribution of activin receptor–like kinase 5 (transforming growth factor β receptor type I) signaling to the fibrotic phenotype of scleroderma fibroblasts

Arthritis & Rheumatism ◽

10.1002/art.21725 ◽

2006 ◽

Vol 54 (4) ◽

pp. 1309-1316 ◽

Cited By ~ 66

Author(s):

Yunliang Chen ◽

Xu Shi-Wen ◽

Mark Eastwood ◽

Carol M. Black ◽

Christopher P. Denton ◽

...

Keyword(s):

Growth Factor ◽

Receptor Type ◽

Type I ◽

Activin Receptor ◽

Receptor Like Kinase ◽

Increased levels of transforming growth factor β receptor type I and up-regulation of matrix gene program: A model of scleroderma

Arthritis & Rheumatism ◽

10.1002/art.22063 ◽

2006 ◽

Vol 54 (9) ◽

pp. 3011-3021 ◽

Cited By ~ 53

Author(s):

Jaspreet Pannu ◽

Humphrey Gardner ◽

Jeffrey R. Shearstone ◽

Edwin Smith ◽

Maria Trojanowska

Keyword(s):

Growth Factor ◽

Receptor Type ◽

Type I ◽

Matrix Gene ◽

Transforming growth factor-β 3 (Tgf-β 3) down-regulates Tgf-β receptor type I (Tβ r-I) during rescue of cranial sutures from osseous obliteration

Orthodontics and Craniofacial Research ◽

10.1034/j.1600-0544.2002.01179.x ◽

2002 ◽

Vol 5 (1) ◽

pp. 5-16 ◽

Cited By ~ 28

Author(s):

LA Opperman ◽

V Galanis ◽

AR Williams ◽

K Adab

Keyword(s):

Growth Factor ◽

Receptor Type ◽

Cranial Sutures ◽

Type I ◽

Preclinical assessment of galunisertib (LY2157299 monohydrate), a first-in-class transforming growth factor-β receptor type I inhibitor

Oncotarget ◽

10.18632/oncotarget.23795 ◽

2017 ◽

Vol 9 (6) ◽

pp. 6659-6677 ◽

Cited By ~ 42

Author(s):

Jonathan M. Yingling ◽

William T. McMillen ◽

Lei Yan ◽

Huocong Huang ◽

J. Scott Sawyer ◽

...

Keyword(s):

Growth Factor ◽

Receptor Type ◽

Type I ◽

Int7G24A Variant of Transforming Growth Factor-β Receptor Type I Is Associated with Invasive Breast Cancer

Clinical Cancer Research ◽

10.1158/1078-0432.ccr-05-1518 ◽

2006 ◽

Vol 12 (2) ◽

pp. 392-397 ◽

Cited By ~ 38

Author(s):

Taiping Chen ◽

Chad R. Jackson ◽

Andrew Link ◽

Michael P. Markey ◽

Bruce M. Colligan ◽

...

Keyword(s):

Breast Cancer ◽

Growth Factor ◽

Invasive Breast Cancer ◽

Receptor Type ◽

Type I ◽