The Auditory Brainstem Response of Aged Guinea Pigs

1998 ◽  
Vol 118 (5) ◽  
pp. 673-680 ◽  
Author(s):  
Neil J. Ingham, Sally K. Thornton,
Keyword(s):  
Auditory Brainstem Response ◽  
Guinea Pigs ◽  
Auditory Brainstem ◽  
Brainstem Response

Effects of noise exposure on neonatal auditory brainstem response thresholds in pregnant guinea pigs at different gestational periods

2016 ◽  
Vol 43 (1) ◽  
pp. 78-86
Author(s):  
Chihiro Morimoto ◽  
Kazuhiko Nario ◽  
Tadashi Nishimura ◽  
Ryota Shimokura ◽  
Hiroshi Hosoi ◽  
...  
Keyword(s):  
Auditory Brainstem Response ◽  
Guinea Pigs ◽  
Noise Exposure ◽  
Auditory Brainstem ◽  
Brainstem Response ◽  
Response Thresholds

Mitochondria-Targeted Antioxidant Mitoquinone Reduces Cisplatin-Induced Ototoxicity in Guinea Pigs

2016 ◽  
Vol 156 (3) ◽  
pp. 543-548 ◽  
Author(s):  
Alan D. Tate ◽  
Patrick J. Antonelli ◽  
Kyle R. Hannabass ◽  
Carolyn O. Dirain
Keyword(s):  
Hearing Loss ◽  
Auditory Brainstem Response ◽  
Guinea Pigs ◽  
Outer Hair Cell ◽  
Auditory Brainstem ◽  
Response Threshold ◽  
Saline Control ◽  
Control Group ◽  
Cochlear Hair Cells ◽  
Brainstem Response

Objective To determine if mitoquinone (MitoQ) attenuates cisplatin-induced hearing loss in guinea pigs. Study Design Prospective and controlled animal study. Setting Academic, tertiary medical center. Subjects and Methods Guinea pigs were injected subcutaneously with either 5 mg/kg MitoQ (n = 9) or normal saline (control, n = 9) for 7 days and 1 hour before receiving a single dose of 10 mg/kg cisplatin. Auditory brainstem response thresholds were measured before MitoQ or saline administration and 3 to 4 days after cisplatin administration. Results Auditory brainstem response threshold shifts after cisplatin treatment were smaller by 28 to 47 dB in guinea pigs injected with MitoQ compared with those in the control group at all tested frequencies (4, 8, 16, and 24 kHz, P = .0002 to .04). Scanning electron microscopy of cochlear hair cells showed less outer hair cell loss and damage in the MitoQ group. Conclusion MitoQ reduced cisplatin-induced hearing loss in guinea pigs. MitoQ appears worthy of further investigation as a means of preventing cisplatin ototoxicity in humans.

scholarly journals Electrically Evoked Auditory Brainstem Response by Using Bionic Auditory Membrane in Guinea Pigs

2013 ◽  
Vol 8 (3) ◽  
pp. 198-208 ◽  
Author(s):  
Hirofumi SHINTAKU ◽  
Takatoshi INAOKA ◽  
Takayuki NAKAGAWA ◽  
Satoyuki KAWANO ◽  
Juichi ITO
Keyword(s):  
Auditory Brainstem Response ◽  
Guinea Pigs ◽  
Auditory Brainstem ◽  
Brainstem Response

Auditory brainstem response in the lesser scaup, a species of diving duck

2010 ◽  
Author(s):  
Sara C. Therrien ◽  
Catherine E. Carr ◽  
Elizabeth F. Brittan-Powell ◽  
Alicia M. Wells-Berlin
Keyword(s):  
Auditory Brainstem Response ◽  
Auditory Brainstem ◽  
Diving Duck ◽  
Lesser Scaup ◽  
Brainstem Response
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