Report of a new meq gene size: The first study on genetic characterisation of Marek’s disease viruses circulating in Iranian commercial layer and backyard chicken

2021 ◽  
pp. 1-8
Author(s):  
A. Molouki ◽  
A. Ghalyanchilangeroudi ◽  
M. Abdoshah ◽  
A. Shoushtari ◽  
A. Abtin ◽  
...  
Keyword(s):  
Marek's Disease ◽  
Marek’S Disease ◽  
Gene Size ◽  
Genetic Characterisation ◽  
Backyard Chicken ◽  
Meq Gene

scholarly journals Characterization of Marek’s disease virus and phylogenetic analyses of meq gene from an outbreak in poultry in Meghalaya of Northeast India

VirusDisease ◽  
2018 ◽  
Vol 29 (2) ◽  
pp. 167-172 ◽  
Author(s):  
Kekungu-u Puro ◽  
Uttaran Bhattacharjee ◽  
Samprity Baruah ◽  
Arnab Sen ◽  
Samir Das ◽  
...  
Keyword(s):  
Disease Virus ◽  
Phylogenetic Analyses ◽  
Northeast India ◽  
Marek's Disease Virus ◽  
Marek's Disease ◽  
Marek’S Disease Virus ◽  
Marek’S Disease ◽  
Meq Gene

scholarly journals Molecular characterization of the meq gene of Marek's disease viruses detected in unvaccinated backyard chickens reveals the circulation of low- and high-virulence strains

2019 ◽  
Vol 98 (8) ◽  
pp. 3130-3137 ◽  
Author(s):  
Giulia Mescolini ◽  
Caterina Lupini ◽  
Viviana Felice ◽  
Alessandro Guerrini ◽  
Flavio Silveira ◽  
...  
Keyword(s):  
Molecular Characterization ◽  
Marek's Disease ◽  
Marek’S Disease ◽  
High Virulence ◽  
Backyard Chickens ◽  
Meq Gene

scholarly journals Unusual Gross Presentation of Sarcocystis-Like Pectoral Muscle Lymphoma Attributed to Marek’s Disease in a Backyard Chicken

2017 ◽  
Vol 26 (1) ◽  
pp. 3-6
Author(s):  
Carlos Daniel Gornatti Churria ◽  
Panayiotis Loukopoulos ◽  
Javier Origlia ◽  
Nancy Arias ◽  
Miguel Herrero Loyola ◽  
...  
Keyword(s):  
Pectoral Muscle ◽  
Marek's Disease ◽  
Marek’S Disease ◽  
Backyard Chicken

Isolation of a Field Marek’s Disease Virus with Acute Oncogenicity from Tibetan Chickens in China and Sequence Analysis of Oncogenic Genes

2011 ◽  
Vol 343-344 ◽  
pp. 538-544
Author(s):  
Ming Xing Tian ◽  
Rui Deng ◽  
Yang Zhao ◽  
Min Li ◽  
San Jie Cao ◽  
...  
Keyword(s):  
Disease Virus ◽  
Challenge Test ◽  
Point Mutations ◽  
Repeated Sequence ◽  
Marek's Disease Virus ◽  
Marek's Disease ◽  
Marek’S Disease Virus ◽  
Marek’S Disease ◽  
Specific Pathogen ◽  
Meq Gene

A field Marek’s disease virus (MDV), named as BY strain, was firstly isolated from Tibetan chickens in Sichuan province, China, by method of co-cultivation of the lymphocytes with duck embryo fibroblasts (DEF). Analysis of the oncogenic genes showed that there were 2 copies of 132-bp repeated sequence in long terminal repeat of the BY strain, The nucleotide and amino acid sequence identities of Meq gene of BY strain with other prevalent MDV strains in China were 97.6-100.0% and 98.8-100.0%, respectively, and some point mutations assumed to be relevant to the oncogenecity of MDV also existed in the Meq gene of BY strain. The result of animal challenge test on specific-pathogen-free (SPF) chickens showed lymphomas may occur in a variety of organs as early as 18 days post challenge, and the rate of tumor occurrences and mortalities reached to 73.33% and 66.67% in HVT immunized chickens, respectively. In conclusion, an MDV strain charac-terized of acute oncogenicity was isolated from Tibetan chickens in China, though there were no obvious difference between the oncogenic genes of this strain and other virulent MDV strains isolated in China in recent years.

scholarly journals Difference in the meq Gene between Oncogenic and Attenuated Strains of Marek's Disease Virus Serotype 1.

2000 ◽  
Vol 62 (3) ◽  
pp. 287-292 ◽  
Author(s):  
Sung-Il LEE ◽  
Michihiro TAKAGI ◽  
Kazuhiko OHASHI ◽  
Chihiro SUGIMOTO ◽  
Misao ONUMA
Keyword(s):  
Disease Virus ◽  
Marek's Disease Virus ◽  
Marek's Disease ◽  
Marek’S Disease Virus ◽  
Marek’S Disease ◽  
Virus Serotype ◽  
Serotype 1 ◽  
Meq Gene

scholarly journals Visceral Marek's disease in white-peafowl (Pavo cristatus)

2016 ◽  
Vol 68 (6) ◽  
pp. 1602-1608 ◽  
Author(s):  
G.R. Blume ◽  
S.P. Cardoso ◽  
M.L.B. Oliveira ◽  
M.P. Matiolli ◽  
S.Y.M. Gómez ◽  
...  
Keyword(s):  
Molecular Detection ◽  
Marek's Disease ◽  
Marek’S Disease ◽  
Gallid Herpesvirus ◽  
Gallid Herpesvirus 2 ◽  
Pavo Cristatus ◽  
Serotype 1 ◽  
Template Dna ◽  
Current Report ◽  
Meq Gene

ABSTRACT Marek's disease (MD) is a lymphoproliferative disorder caused by Gallid herpesvirus 2 (MDV) that infects mainly domestic gallinaceous birds although wild birds may occasionally be affected. The current report describes the anatomopathological and molecular findings of a case of MD in a white-peafowl (Pavo cristatus). The signs included apathy, hyporexia, and diarrhea. Grossly, 0.5 to 1.5cm in diameter, yellow, soft nodules were observed in the skeletal muscle, lung, kidney, air sacs, small intestine, heart, ovary, ventriculus, and proventriculus. Microscopically, numerous atypical round neoplastic cells were noted. The molecular detection of MDV DNA was implemented to amplify part of the meq gene and products were sequenced for the phylogenetic analysis. Template DNA was obtained from tissues of the affected bird and from blood of all the gallinaceous birds of the Zoo. The expected amplicon for the partial amplification of MDV meq gene was obtained and the amplicons were sequenced. Sequences obtained enabled grouping the strain (accession no. KT768121) with MDV serotype 1 strains from the GenBank. Based on the anatomopathological and molecular findings, the diagnosis of MD in a white-peafowl was reached, and to the authors' knowledge, no previous report regarding MD was published in Pavo cristatus.

scholarly journals Deletion of the meq gene significantly decreases immunosuppression in chickens caused by pathogenic marek's disease virus

2011 ◽  
Vol 8 (1) ◽  
pp. 2 ◽  
Author(s):  
Yanpeng Li ◽  
Aijun Sun ◽  
Shuai Su ◽  
Peng Zhao ◽  
Zhizhong Cui ◽  
...  
Keyword(s):  
Disease Virus ◽  
Marek's Disease Virus ◽  
Marek's Disease ◽  
Marek’S Disease Virus ◽  
Marek’S Disease ◽  
Meq Gene
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