Zn(ANA)2Cl2 complex as efficient catalyst for the synthesis of dihydropyrano[2,3-c]pyrazoles in aqueous medium via one-pot multicomponent reaction: a green approach

2018 ◽  
Vol 48 (20) ◽  
pp. 2642-2651 ◽  
Author(s):  
Ramaiah Konakanchi ◽  
Venkata Bharat Nishtala ◽  
Shravankumar Kankala ◽  
Laxma Reddy Kotha
Keyword(s):  
Aqueous Medium ◽  
Multicomponent Reaction ◽  
One Pot ◽  
Efficient Catalyst ◽  
Green Approach

scholarly journals Green approach for synthesis of bioactive Hantzsch 1,4-dihydropyridine derivatives based on thiophene moiety via multicomponent reaction

2017 ◽  
Vol 4 (6) ◽  
pp. 170006 ◽  
Author(s):  
M. G. Sharma ◽  
D. P. Rajani ◽  
H. M. Patel
Keyword(s):  
Antifungal Activity ◽  
Multicomponent Reaction ◽  
Breast Tumour ◽  
Ceric Ammonium Nitrate ◽  
One Pot ◽  
Solvent Free Condition ◽  
Green Approach ◽  
Short Period ◽  
Dihydropyridine Derivatives

A novel green and efficient one-pot multicomponent reaction of dihydropyridine derivatives was reported as having good to excellent yield. In the presence of the catalyst ceric ammonium nitrate (CAN), different 1,3-diones and same starting materials as 5-bromothiophene-2-carboxaldehyde and ammonium acetate were used at room temperature under solvent-free condition for the Hantzsch pyridine synthesis within a short period of time. All compounds were evaluated for their in vitro antibacterial and antifungal activity and, interestingly, we found that 5(b–f) show excellent activity compared with Ampicillin, whereas only the 5e compound shows excellent antifungal activity against Candida albicans compared with griseofulvin. The cytotoxicity of all compounds has been assessed against breast tumour cell lines (BT-549), but no activity was found. The X-ray structure of one such compound, 5a , viewed as a colourless block crystal, corresponded accurately to a primitive monoclinic cell.

Diastereoselective Synthesis of Functionalised Trans-Tetrahydrobenzofuran-4-Ones in an Aqueous Medium by using DABCO as an Efficient Catalyst

2017 ◽  
Vol 41 (11) ◽  
pp. 657-660 ◽  
Author(s):  
Mohammad Reza Salari ◽  
Mohammad H. Mosslemin ◽  
Alireza Hassanabadi
Keyword(s):  
Aqueous Medium ◽  
High Purity ◽  
Reaction Times ◽  
Diastereoselective Synthesis ◽  
Efficient Synthesis ◽  
One Pot ◽  
Efficient Catalyst ◽  
Pyridinium Bromide ◽  
Work Up

A one-pot, efficient synthesis of 11 novel 2,3-diacylated trans-tetrahydrobenzofuran-4-one derivatives has been achieved via a three-component condensation of a N-(4-halophenacyl)-pyridinium bromide, a cyclic 1,3-diketone such as 5,5-dimethyl-1,3-cyclohexanedione (dimedone) or cyclohexane-1,3-dione and an arylglyoxal in the presence of catalytic amounts of 1,4-diaza-bicyclo[2.2.2]octane (DABCO) in water under reflux conditions. The attractive features of the method are excellent yields and high purity, short reaction times, easy work-up, and use of an inexpensive and non-toxic catalyst.

Synthesis of Trans-6-(4-Chlorobenzoyl)-7-(Aryl)-1,3-Dimethyl-6,7-Dihydrofuro[3,2-d]Pyrimidine-2,4-Diones Using Choline Hydroxide as an Efficient Catalyst in an Aqueous Medium

2017 ◽  
Vol 41 (3) ◽  
pp. 139-142 ◽  
Author(s):  
Maryam Salari ◽  
Alireza Hassanabadi ◽  
Mohammad H. Mosslemin
Keyword(s):  
Aqueous Medium ◽  
Aromatic Aldehyde ◽  
Reaction Times ◽  
Efficient Synthesis ◽  
One Pot ◽  
Efficient Catalyst ◽  
Excellent Yield ◽  
One Pot Condensation

A green and efficient synthesis of the trans-6-(4-chlorobenzoyl)-7-(aryl)-1,3-dimethyl-6,7-dihydrofuro[3,2-d]pyrimidine-2,4-diones has been achieved via a three-component, one-pot condensation of 2-[2-(4-chlorophenyl)-2-oxoethyl)]isoquinolinium bromide with 1,3-dimethylbarbituric acid and an aromatic aldehyde in the presence of catalytic amounts of choline hydroxide in water under reflux conditions. This gives trans-6-(4-chlorobenzoyl)-7-(aryl)-1,3-dimethyl-6,7-dihydrofuro[3,2-d]pyrimidine-2,4-diones in excellent yield and in short reaction times.

Organocatalyst Mediated One Pot Synthesis of 4H-furo[3,4-b]pyran, 4Hbenzo[ g]chromene and 1H-benzo[b]xanthene Derivatives in Aqueous Medium: A Green Approach

2018 ◽  
Vol 5 (1) ◽  
pp. 51-57 ◽  
Author(s):  
Shailesh Singh ◽  
Jyoti Tiwari ◽  
Deepali Jaiswal ◽  
Amit Kumar Sharma ◽  
Jaya Singh ◽  
...  
Keyword(s):  
Aqueous Medium ◽  
One Pot ◽  
One Pot Synthesis ◽  
Green Approach ◽  
Xanthene Derivatives

An efficient catalyst-free chemoselective multicomponent reaction for the synthesis of pyrimidine functionalized pyrrolo-annelated derivatives

RSC Advances ◽  
2015 ◽  
Vol 5 (31) ◽  
pp. 24327-24335 ◽  
Author(s):  
Yuvaraj Dommaraju ◽  
Somadrita Borthakur ◽  
Nimmakuri Rajesh ◽  
Dipak Prajapati
Keyword(s):  
Multicomponent Reaction ◽  
Reaction Conditions ◽  
One Pot ◽  
Efficient Catalyst ◽  
Catalyst Free ◽  
High Yields

An efficient catalyst-free, one-pot multicomponent reaction has been developed for the synthesis of pyrimidine functionalized pyrrolo-annelated derivatives. The method offers easy and column free separation, mild reaction conditions and high yields.

scholarly journals Silver Nanoparticles Catalyzed Synthesis and Antimicrobial Activity of 2-Amino-4H-Chromenes

2021 ◽  
Vol 10 (4) ◽  
pp. 2715-2721
Keyword(s):  
Antimicrobial Activity ◽  
Silver Nanoparticles ◽  
Antifungal Activity ◽  
Aqueous Medium ◽  
Alternaria Alternata ◽  
Room Temperature ◽  
One Pot ◽  
Environment Friendly ◽  
Green Approach ◽  
Operational Simplicity

A simple and one-pot protocol has been developed to synthesize bioactive 2-amino-4H-chromenes by using silver nanoparticles (AgNp) as a catalyst at room temperature in an aqueous medium. This method provides operational simplicity and an environment-friendly green approach. All the synthesized compounds were evaluated for antifungal activity against Alternaria alternata.

scholarly journals SBA-15@methenamine-HPA: a novel, simple, and efficient catalyst for one-pot three-component synthesis of 2-amino-4H-chromene derivatives in aqueous medium

2017 ◽  
Vol 43 (10) ◽  
pp. 5467-5483 ◽  
Author(s):  
Samahe Sadjadi ◽  
Majid M. Heravi ◽  
Vahideh Zadsirjan ◽  
Maryam Ebrahimizadeh
Keyword(s):  
Aqueous Medium ◽  
One Pot ◽  
Efficient Catalyst
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