Multifunctional 1,10-phenanthroline derivative and its metal complexes as an anti-Alzheimer’s agent: structure-based drug design, synthesis, characterization and pharmacological studies

2020 ◽  
Vol 73 (23) ◽  
pp. 3267-3290
Author(s):  
E. H. Edinsha Gladis ◽  
K. Nagashri ◽  
A. Suman ◽  
J. Joseph
Keyword(s):  
Drug Design ◽  
Metal Complexes ◽  
Structure Based Drug Design ◽  
Design Synthesis ◽  
Pharmacological Studies ◽  
Agent Structure

Design, synthesis and evaluation of diphenyl ether analogues as antitubercular agents

RSC Advances ◽  
2016 ◽  
Vol 6 (112) ◽  
pp. 110571-110582 ◽  
Author(s):  
Bharathkumar Inturi ◽  
Gurubasavaraj V. Pujar ◽  
Madhusudhan N. Purohit ◽  
Viswanathan B. Iyer ◽  
Sowmya G. S. ◽  
...  
Keyword(s):  
Mycobacterium Tuberculosis ◽  
Drug Design ◽  
Acyl Carrier Protein ◽  
Diphenyl Ether ◽  
Design Approach ◽  
Carrier Protein ◽  
Antitubercular Agents ◽  
Structure Based Drug Design ◽  
Design Synthesis ◽  
Diphenyl Ethers

We herein report the investigation of new diphenyl ethers asMycobacterium tuberculosisenoyl-acyl carrier protein reductase (InhA) inhibitors by structure-based drug design approach.

scholarly journals Structure-Based Drug Design, Synthesis and Antitumor Activities of Novel CDK7 Inhibitors

2009 ◽  
Vol 25 (10) ◽  
pp. 2107-2112 ◽  
Author(s):  
LIU Tao ◽  
◽  
SUN Mao-Tang ◽  
DONG Xiao-Wu ◽  
REN Xin ◽  
...  
Keyword(s):  
Drug Design ◽  
Antitumor Activities ◽  
Structure Based Drug Design ◽  
Design Synthesis

Structure-based drug design, synthesis and screening of MmaA1 inhibitors as novel anti-TB agents

2020 ◽  
Author(s):  
Hymavathi Veeravarapu ◽  
Vasavi Malkhed ◽  
Kiran Kumar Mustyala ◽  
Rajender Vadija ◽  
Ramesh Malikanti ◽  
...  
Keyword(s):  
Drug Design ◽  
Structure Based Drug Design ◽  
Design Synthesis

Structure based drug design, synthesis and evaluation of 4-(benzyloxy)-1-phenylbut-2-yn-1-ol derivatives as 5-lipoxygenase inhibitors

2012 ◽  
Vol 47 ◽  
pp. 351-359 ◽  
Author(s):  
Nimmanapalli P. Reddy ◽  
T. Chandramohan Reddy ◽  
Polamarasetty Aparoy ◽  
Chandrani Achari ◽  
P. Ramu Sridhar ◽  
...  
Keyword(s):  
Drug Design ◽  
Structure Based Drug Design ◽  
Design Synthesis ◽  
Lipoxygenase Inhibitors
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