Brain injury following neuroleptic malignant syndrome: Case report and review of the literature

Brain Injury ◽  
2006 ◽  
Vol 20 (7) ◽  
pp. 775-778 ◽  
Author(s):  
Anna Labuda ◽  
Nora Cullen
1986 ◽  
Vol 31 (1) ◽  
pp. 66-69 ◽  
Author(s):  
Margaret Schibuk ◽  
Debbie Schachter

The authors present a case report in which an agitated response to antidepressants preceded the neuroleptic malignant syndrome (NMS). In a review of 64 cases of NMS in the literature, they found that 80% were described as agitated prior to the development of the syndrome. Polypharmacy was common. A review of the literature on theories of pathogenesis involving sympathetic amines other than dopamine is presented to explain this phenomena. It is suggested that these toxic reactions to medication can be interpreted as resulting from a relative NE/DA excess, in which antidepressants increase the numerator, while neuroleptics functionally decrease the denominator. It is recommended that where an agitated response to antidepressants is observed, neuroleptics should be used only with considerable caution.


2008 ◽  
Vol 32 (8) ◽  
pp. 1998-1999 ◽  
Author(s):  
Lai Gwen Chan ◽  
Jimmy Lee ◽  
Boon Tat Ng ◽  
Ee Lian Lee ◽  
Hong Choon Chua ◽  
...  

Brain Injury ◽  
2014 ◽  
Vol 28 (12) ◽  
pp. 1617-1621 ◽  
Author(s):  
Andrew J. Grossbach ◽  
Taylor J. Abel ◽  
Janel Smietana ◽  
Nader Dahdaleh ◽  
Meryl A. Severson ◽  
...  

2021 ◽  
Vol 11 (03) ◽  
pp. 204-209
Author(s):  
Adil Belhachmi ◽  
Yao Christian Hugues Dokponou ◽  
Fernand Nathan Imoumby ◽  
Napoléon Imbunhe ◽  
Sofia El Akroud ◽  
...  

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