Association of high sensitivity C-reactive protein and abdominal aortic aneurysm: a meta-analysis and systematic review

2017 ◽  
Vol 33 (12) ◽  
pp. 2145-2152 ◽  
Author(s):  
Yunpeng Wang ◽  
Guanghui Shen ◽  
Haiyang Wang ◽  
Ye Yao ◽  
Qingfeng Sun ◽  
...  
Keyword(s):  
Systematic Review ◽  
Abdominal Aortic Aneurysm ◽  
Aortic Aneurysm ◽  
Meta Analysis ◽  
High Sensitivity ◽  
C Reactive Protein ◽  
Reactive Protein ◽  
Abdominal Aortic

The Influence of COX-2 Single Nucleotide Polymorphisms on Abdominal Aortic Aneurysm Development and the Associated Inflammation

Angiology ◽  
2009 ◽  
Vol 60 (5) ◽  
pp. 576-581 ◽  
Author(s):  
Stephen A. Badger ◽  
Chee V. Soong ◽  
Ian S. Young ◽  
Ann McGinty ◽  
Caroline Mercer ◽  
...  
Keyword(s):  
Abdominal Aortic Aneurysm ◽  
Aortic Aneurysm ◽  
Serum Concentration ◽  
High Sensitivity ◽  
Nucleotide Polymorphisms ◽  
C Reactive Protein ◽  
Single Nucleotide ◽  
Reactive Protein ◽  
Abdominal Aortic ◽  
Cox 2

Introduction Cyclooxygenase (COX)-2 influences cardiovascular disease and serum concentration of high-sensitivity C-reactive protein (hsCRP). The study purpose was to determine the influence of single nucleotide polymorphisms (SNPs) of the COX-2 gene on abdominal aortic aneurysm (AAA) development and serum hsCRP concentrations. Patients and Methods Patients with AAA and disease-free controls were recruited. High-sensitivity C-reactive protein was measured by an enzyme-linked immunosorbent assay (ELISA) test. The distributions of COX-2 SNPs were investigated (rs20417 and rs4648307). The influence of the COX-2 SNPs on the hsCRP serum concentration was assessed. Results A total of 230 patients with AAA and 279 controls were included. No difference was found in the genotype distribution of the COX-2 SNPs rs20417 ( P = .26) and rs4648307 ( P = .90). They did not influence the hsCRP concentration ( P = .24 and P = .61, respectively). Haplotype analysis of COX-2 SNPs revealed no difference. Conclusion These COX-2 SNPs do not play any role in AAA development and do not influence serum hsCRP. These results differentiate AAA development from atherosclerotic diseases.

scholarly journals Prediction of abdominal aortic aneurysm calcification by means of variation of high-sensitivity C-reactive protein

2016 ◽  
Vol 5 ◽  
pp. 204800401668217 ◽  
Author(s):  
Emirena Garrafa ◽  
Alessio Giacomelli ◽  
Marco Ravanelli ◽  
Patrizia Dell’Era ◽  
Michele Peroni ◽  
...  
Keyword(s):  
Abdominal Aortic Aneurysm ◽  
Aortic Aneurysm ◽  
High Sensitivity ◽  
C Reactive Protein ◽  
Reactive Protein ◽  
Abdominal Aortic

scholarly journals Plasma C-Reactive Protein and Abdominal Aortic Aneurysm

2018 ◽  
Vol 131 (21) ◽  
pp. 2630-2633 ◽  
Author(s):  
Xue-Ying Qin ◽  
Juan Juan ◽  
Xiao Xiang ◽  
Ying-Qi Wei ◽  
Shang-Wei Zuo ◽  
...  
Keyword(s):  
Abdominal Aortic Aneurysm ◽  
Aortic Aneurysm ◽  
C Reactive Protein ◽  
Reactive Protein ◽  
Abdominal Aortic
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