Imaging features of foreign body granuloma in the lower extremities mimicking a soft tissue neoplasm

Foreign body granuloma develops following a skin penetrating injury with retention of a foreign body, which subsequently causes a reactive inflammatory granulation tissue around it. It can mimic as a pseudotumor; hence, its early detection and diagnosis with imaging can help in its management and prevent further complications. We report a 10-year-old boy with swelling on the dorsum of the hand causing scalloping of the 3rd metacarpal presenting as pseudotumor and was confirmed to be a foreign body (thorn) granuloma on ultrasonography and magnetic resonance imaging (MRI). The characteristic appearance of foreign body in soft tissue on ultrasound is an echogenic structure giving posterior acoustic shadowing, and on MRI it typically appears as a low signal intensity structure on T1- and T2-weighted images with peripheral ring enhancement. Hence, the possibility of a foreign body granuloma should be ruled out in cases of suspected soft tissue neoplasm in extremities, despite no significant history of previous trauma.

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Fibroma-like PEComa: a newly recognized soft tissue neoplasm in tuberous sclerosis patients—imaging features and review of literature

Skeletal Radiology ◽

10.1007/s00256-021-03923-4 ◽

2021 ◽

Author(s):

Gitanjali Bajaj ◽

Matthew R. Lindberg ◽

Winson Chee ◽

Debopam Samanta ◽

Avneesh Chhabra

Keyword(s):

Soft Tissue ◽

Tuberous Sclerosis ◽

Imaging Features ◽

Review Of Literature ◽

Soft Tissue Neoplasm

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Suspected cerebral foreign body granuloma following endovascular treatment of intracranial aneurysm: imaging features

Neuroradiology ◽

10.1007/s00234-014-1440-1 ◽

2014 ◽

Vol 57 (1) ◽

pp. 71-73 ◽

Cited By ~ 10

Author(s):

David Minks ◽

Dennis Briley ◽

Ursula Schulz ◽

Wilhelm Küker

Keyword(s):

Foreign Body ◽

Intracranial Aneurysm ◽

Endovascular Treatment ◽

Foreign Body Granuloma ◽

Imaging Features

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Foreign Bodies in Tendons

Journal of Hand Surgery (European Volume) ◽

10.1016/0266-7681(89)90022-3 ◽

1989 ◽

Vol 14 (1) ◽

pp. 84-85 ◽

Cited By ~ 11

Author(s):

L. Jozsa ◽

A. Reffy ◽

Susanne Demel ◽

J. B. Balint

Keyword(s):

Foreign Body ◽

Foreign Bodies ◽

Lower Extremities ◽

Upper Extremities ◽

Foreign Body Granuloma ◽

Lower Limbs ◽

Upper Limbs ◽

Foreign Material ◽

Glass Sand

At the National Institute of Traumatology in Budapest, a search has been made for foreign bodies in tendons over the last 15 years. 53 foreign bodies have been found in 931 tendons removed at operation and 45 foreign bodies in 950 tendon samples at autopsy. The foreign material was found to be organic in 29 cases, metal in 20 cases and plastic in six cases. In the others, glass, sand, mineral grease and textiles could be detected. In 33 cases the material could not be identified. The foreign bodies were found in the tendons of the upper extremities in 51 cases and the lower extremities in 47 cases. Foreign bodies in the tendons were more likely to cause problems in the upper limbs than in the lower limbs: these problems were purulent tendonitis, necrosis, foreign body granuloma, fibrosis and peritendonitis and calcification.

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Foreign Body Granulomas Induced by Intramuscular Leuprorelin Acetate Injection for Prostate Cancer: Clinical Mimics of Soft Tissue Sarcoma

Case Reports in Oncological Medicine ◽

10.1155/2015/947040 ◽

2015 ◽

Vol 2015 ◽

pp. 1-5 ◽

Cited By ~ 1

Author(s):

Khin Thway ◽

Dirk C. Strauss ◽

Myles J. Smith ◽

Cyril Fisher

Keyword(s):

Foreign Body ◽

Soft Tissue ◽

Clinical Intervention ◽

Clinical Suspicion ◽

Granulomatous Reaction ◽

Soft Tissue Neoplasm ◽

Leuprorelin Acetate ◽

Depot Injection ◽

Diagnostic Confusion ◽

Soft Tissue Masses

We describe two cases of florid, foreign body granulomatous reaction occurring in the upper arms of males in their eighth decade, who were undergoing treatment with depot injection of leuprorelin acetate for prostatic carcinoma. These patients presented with rapidly enlarging extremity soft tissue masses and were referred to a tertiary sarcoma center with clinical suspicion of a primary soft tissue neoplasm. The occurrence of injection site granulomas secondary to leuprorelin acetate administration is rarely known outside the urological and dermatological communities, and their recognition is important due to the spectrum of clinical differential diagnoses and potential for diagnostic confusion with metastatic prostatic cancer and primary sarcoma and in order to avoid unnecessary stress and clinical intervention for patients.

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Fascia Lata Donor Site Foreign Body Granuloma: An Unusual Presentation of a Rare Mimic of Soft Tissue Sarcoma

Surgical Science ◽

10.4236/ss.2021.123005 ◽

2021 ◽

Vol 12 (03) ◽

pp. 31-36

Author(s):

Olakunle F. Babalola ◽

Adedayo I. Salawu ◽

Abiodun I. Okunlola ◽

Oladipo Omoseebi

Keyword(s):

Foreign Body ◽

Soft Tissue ◽

Soft Tissue Sarcoma ◽

Donor Site ◽

Fascia Lata ◽

Foreign Body Granuloma ◽

Unusual Presentation

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An Unusual Presentation of Foreign Body Granuloma of Ankle Mimicking a Neoplastic Lesion

Journal of Evolution of Medical and Dental Sciences ◽

10.14260/jemds/2021/322 ◽

2021 ◽

Vol 10 (20) ◽

pp. 1547-1550

Author(s):

Mohit Dadlani ◽

Ankit Jaiswal ◽

Kiran Saoji ◽

Gajanan Pisulkar

Keyword(s):

Foreign Body ◽

Soft Tissue ◽

Foreign Body Granuloma ◽

Unusual Presentation ◽

Retained Foreign Body ◽

Neoplastic Lesion ◽

Wood Particles ◽

Diagnostic Confusion

Granulomas of foreign body can mimic features of neoplasia, especially when history and odd location create diagnostic confusion. Penetrating foot wounds are not that unusual. Thorns or wood particles that are stored in the foot are the cause of granuloma of the alien body. Later, soft tissue and osseous complications can arise from an untreated retained foreign body.

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