Characterization of Poly(Ethylene Oxide) as a Drug Carrier in Hot-Melt Extrusion

2006 ◽  
Vol 32 (8) ◽  
pp. 991-1002 ◽  
Author(s):  
Lei Li ◽  
Omar AbuBaker ◽  
Zezhi J. Shao
2014 ◽  
Vol 679 ◽  
pp. 57-62
Author(s):  
Conor Coffey ◽  
Joshua H. Yoon ◽  
Luke M. Geever

In this study, xanthan gum and poly (ethylene oxide) (PEO) were blended via hot melt extrusion. Results showed that PEO acted as a plasticiser and lowered the melt viscosity of xanthan gum/PEO blends. For example, melt flow rate and torque level were observed to decrease at increasing percent compositions of PEO in the blend. Breakdown testing demonstrated that xanthan gum accelerates the breakdown rates compared to the breakdown rate of 100 % PEO extrudate samples.


2005 ◽  
Vol 94 (10) ◽  
pp. 2232-2245 ◽  
Author(s):  
Suneela Prodduturi ◽  
Rahul V. Manek ◽  
William M. Kolling ◽  
Steven P. Stodghill ◽  
Michael A. Repka

2004 ◽  
Vol 37 (18) ◽  
pp. 7064-7064
Author(s):  
Yumi Matsumiya ◽  
Nitash P. Balsara ◽  
John B. Kerr ◽  
Tadashi Inoue ◽  
Hiroshi Watanabe

2010 ◽  
Vol 395 (1-2) ◽  
pp. 53-61 ◽  
Author(s):  
Min Yang ◽  
Peng Wang ◽  
Chien-Yueh Huang ◽  
M. Sherry Ku ◽  
Huiju Liu ◽  
...  

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