In vitro study on binding interaction of quinapril with bovine serum albumin (BSA) using multi-spectroscopic and molecular docking methods

2016 ◽  
Vol 35 (10) ◽  
pp. 2211-2223 ◽  
Author(s):  
Jie-hua Shi ◽  
Dong-qi Pan ◽  
Min Jiang ◽  
Ting-Ting Liu ◽  
Qi Wang
Keyword(s):  
Molecular Docking ◽  
Bovine Serum Albumin ◽  
Serum Albumin ◽  
Bovine Serum ◽  
In Vitro Study ◽  
Vitro Study ◽  
Binding Interaction

In vitro study on the interaction of Mn(II)-DiAmsar with human serum albumin (HSA) and bovine serum albumin (BSA) by spectroscopic and molecular docking methods

2014 ◽  
Vol 12 (4) ◽  
pp. 715-725 ◽  
Author(s):  
Zari Hooshyar ◽  
Ghasem Rezanejade Bardajee ◽  
Pegah Shafagh ◽  
Samira Ghiasvand ◽  
Mohaddeseh Khanjari ◽  
...  
Keyword(s):  
Molecular Docking ◽  
Human Serum Albumin ◽  
Bovine Serum Albumin ◽  
Serum Albumin ◽  
Human Serum ◽  
Bovine Serum ◽  
In Vitro Study ◽  
Vitro Study

In Vitro Study of the Binding of Taxifolin to Bovine Serum Albumin and the Influence of Common Ions on the Binding

2010 ◽  
Vol 39 (4) ◽  
pp. 482-494 ◽  
Author(s):  
Xiaolei Shi ◽  
Xuwen Li ◽  
Yantao Sun ◽  
Wei Wei ◽  
Ruijie Yang ◽  
...  
Keyword(s):  
Bovine Serum Albumin ◽  
Serum Albumin ◽  
Bovine Serum ◽  
In Vitro Study ◽  
Vitro Study

In vitro study of caffeic acid — bovine serum albumin interaction

1988 ◽  
Vol 13 (1) ◽  
pp. 11-14 ◽  
Author(s):  
T. Adzet ◽  
J. Camarasa ◽  
E. Escubedo ◽  
M. Merlos
Keyword(s):  
Bovine Serum Albumin ◽  
Serum Albumin ◽  
Caffeic Acid ◽  
Bovine Serum ◽  
In Vitro Study ◽  
Vitro Study

scholarly journals Design and Synthesis of Novel 1,3-Thiazole and 2-Hydrazinyl-1,3-Thiazole Derivatives as Anti-Candida Agents: In Vitro Antifungal Screening, Molecular Docking Study, and Spectroscopic Investigation of their Binding Interaction with Bovine Serum Albumin

Molecules ◽  
2019 ◽  
Vol 24 (19) ◽  
pp. 3435 ◽  
Author(s):  
Andreea-Iulia Pricopie ◽  
Ioana Ionuț ◽  
Gabriel Marc ◽  
Anca-Maria Arseniu ◽  
Laurian Vlase ◽  
...  
Keyword(s):  
Molecular Docking ◽  
Bovine Serum Albumin ◽  
Serum Albumin ◽  
Bovine Serum ◽  
Rapid Development ◽  
Biologically Active ◽  
Thiazole Derivatives ◽  
Binding Interaction ◽  
Reference Drug

In the context of there being a limited number of clinically approved drugs for the treatment of Candida sp.-based infections, along with the rapid development of resistance to the existing antifungals, two novel series of 4-phenyl-1,3-thiazole and 2-hydrazinyl-4-phenyl-1,3-thiazole derivatives were synthesized and tested in vitro for their anti-Candida potential. Two compounds (7a and 7e) showed promising inhibitory activity against the pathogenic C. albicans strain, exhibiting substantially lower MIC values (7.81 μg/mL and 3.9 μg/mL, respectively) as compared with the reference drug fluconazole (15.62 μg/mL). Their anti-Candida activity is also supported by molecular docking studies, using the fungal lanosterol C14α-demethylase as the target enzyme. The interaction of the most biologically active synthesized compound 7e with bovine serum albumin was investigated through fluorescence spectroscopy, and the obtained data suggested that this molecule might efficiently bind carrier proteins in vivo in order to reach the target site.

Sulfadiazine binds and unfolds bovine serum albumin: an in vitro study

2013 ◽  
Vol 40 (11) ◽  
pp. 6081-6090 ◽  
Author(s):  
Mohd. Sajid Ali ◽  
Hamad A. Al-Lohedan
Keyword(s):  
Bovine Serum Albumin ◽  
Serum Albumin ◽  
Bovine Serum ◽  
In Vitro Study ◽  
Vitro Study
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