Synthesis and characterization of copper–based anticancer compound; in vitro interaction studies with DNA/HSA, SOD mimetic, cytotoxic activity and molecular docking investigation

2020 ◽  
pp. 1-16 ◽  
Author(s):  
Waddhaah M. Al–Asbahy ◽  
Manal Shamsi
Keyword(s):  
Molecular Docking ◽  
Cytotoxic Activity ◽  
Synthesis And Characterization ◽  
Interaction Studies ◽  
In Vitro Interaction ◽  
Anticancer Compound

Synthesis and spectroscopic characterization of diorganotin(iv) complexes of N′-(4-hydroxypent-3-en-2-ylidene)isonicotinohydrazide: chemotherapeutic potential validation by in vitro interaction studies with DNA/HSA, DFT, molecular docking and cytotoxic activity

RSC Advances ◽  
2015 ◽  
Vol 5 (63) ◽  
pp. 50673-50690 ◽  
Author(s):  
Shipra Yadav ◽  
Imtiyaz Yousuf ◽  
Mohammad Usman ◽  
Musheer Ahmad ◽  
Farukh Arjmand ◽  
...  
Keyword(s):  
Molecular Docking ◽  
Cytotoxic Activity ◽  
Chemotherapeutic Agent ◽  
Spectroscopic Characterization ◽  
Carrier Protein ◽  
Interaction Studies ◽  
In Vitro Interaction ◽  
Potential Cancer

A diorganotin(iv) hydrazide complex as a potential cancer chemotherapeutic agent targeting DNA using the carrier protein HSA.

scholarly journals Synthesis, Characterization and Antitumour Activity of Some Butyltin(IV) Cysteaminates and N,N-Dimethylcysteaminates

2000 ◽  
Vol 7 (5) ◽  
pp. 233-236 ◽  
Author(s):  
Marcel Gielen ◽  
Karel Handlir ◽  
Martin Hollein ◽  
Dick de Vos
Keyword(s):  
Cytotoxic Activity ◽  
Antitumour Activity ◽  
Synthesis And Characterization

The synthesis and characterization of four di- and tri-n-butyltin cysteaminates and N,N-dimethylcysteaminates and three protonated / quaternized derivatives are reported. They all exhibit moderate or high in vitro cytotoxic activity. Six of seven compounds presented in this work are more active than cisplatin, etoposide and 5-fluorouracil, but less active than methotrexate and doxorubicin.

Synthesis and characterization of mixed-ligand Zn(II) and Cu(II) complexes including polyamines and dicyano-dithiolate(2-): In vitro cytotoxic activity of Cu(II) compounds

2019 ◽  
Vol 498 ◽  
pp. 119098 ◽  
Author(s):  
Suman Adhikari ◽  
Tirtha Bhattacharjee ◽  
Raymond J. Butcher ◽  
Marina Porchia ◽  
Michele De Franco ◽  
...  
Keyword(s):  
Cytotoxic Activity ◽  
Mixed Ligand ◽  
Synthesis And Characterization

Synthesis and characterization of a new alkyne functionalized bis(pyrazolyl)methane ligand and of its Pd(II) complexes: Evaluation of their in vitro cytotoxic activity

2017 ◽  
Vol 455 ◽  
pp. 677-682 ◽  
Author(s):  
Corrado Di Nicola ◽  
Fabio Marchetti ◽  
Claudio Pettinari ◽  
Riccardo Pettinari ◽  
Fabrizia Brisdelli ◽  
...  
Keyword(s):  
Cytotoxic Activity ◽  
Synthesis And Characterization
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