scholarly journals Dexamethasone on absent end-diastolic flow in umbilical artery, in growth restricted fetuses from early-onset preeclamptic pregnancies and the perinatal outcome

2021 ◽  
Vol 53 (1) ◽  
pp. 1455-1463
Author(s):  
Oana Sorina Tica ◽  
Andrei Adrian Tica ◽  
Doriana Cojocaru ◽  
Mihaela Gheonea ◽  
Irina Tica ◽  
...  
Keyword(s):  
Early Onset ◽  
Perinatal Outcome ◽  
Umbilical Artery ◽  
Diastolic Flow

scholarly journals Correlation of efficacy of cerebro placental ratio with adverse perinatal outcome in clinically suspected IUGR pregnancies

2018 ◽  
Vol 7 (5) ◽  
pp. 1808
Author(s):  
Geeta Singh ◽  
Neerja Gupta ◽  
Sangeeta Singhal ◽  
Pramod Kishor Sharma
Keyword(s):  
Middle Cerebral Artery ◽  
Cerebral Artery ◽  
Perinatal Outcome ◽  
Pulsatility Index ◽  
Umbilical Artery ◽  
Doppler Velocity ◽  
Wave Form ◽  
Adverse Perinatal Outcome ◽  
Diastolic Flow ◽  
Ultrasound Evaluation

Background: IUGR is a most common and complex problem in modern obstetrics. Most commonly use methods to assess fetal condition are BPP and NST which are not sensitive for predicting better perinatal outcome.  Present study was an effort to evaluate the role of ratio of pulsatility index (PI) of middle cerebral artery and umbilical artery which is called cerebro placental ratio as the most sensitive, specific and accurate predictor of adverse perinatal outcome in clinically suspected IUGR Pregnancies.Methods: 50 clinically suspected IUGR Pregnancies attending antenatal clinics Muzaffarnagar Medical College and Hospital, Muzaffarnagar were subjected to Doppler ultrasound evaluation Doppler velocity wave form of umbilical artery and fetal middle cerebral artery were obtained. Pulsatility index ratio of MCA and umbilical artery (cerebro placental ratio) was evaluated in each case. Abnormal ratio is defined as CPR<1.08 considered as cut of value. Ratio was coo related clinically with perinatal outcome.Results: Out of 50 antenatal cases, 63% neonates had birth weight <2.5 kg. There were 6 IUD’S and 44 live births, 9 neonates were admitted to NICU, 7 neonates had 5 min. APGAR score <7 and 13 neonates were born by emergency CS. Of the 6 IUDS, 4 cases had reversal of blood flow umbilical artery and 2 cases had absent diastolic flow. In all cases of reversal Diastolic flow, IUD occurred within 7 days of diagnosis. Conclusions: CPR is the most sensitive, specific and accurate parameter in prediction of adverse perinatal outcome and thus can help in decreasing perinatal mortality.

scholarly journals Prediction of perinatal outcome with umbilical artery Doppler in IUGR fetuses- a prospective analytical study in a tertiary medical college in Tamilnadu, India

2017 ◽  
Vol 6 (3) ◽  
pp. 1097
Author(s):  
Rajarajeswari R. ◽  
V. Thendral
Keyword(s):  
Birth Weight ◽  
Perinatal Mortality ◽  
Perinatal Outcome ◽  
Umbilical Artery ◽  
Uncontrolled Hypertension ◽  
Medical College ◽  
Diastolic Flow ◽  
Lower Segment Cesarean Section ◽  
Doppler Study ◽  
Umbilical Artery Doppler

Background: Umbilical artery Doppler blood flow studies were a better predictor of neonatal outcome than estimated fetal weight alone in intrauterine growth restricted (IUGR) fetuses. Perinatal mortality and morbidity are increased if the umbilical artery Doppler abnormality worsens.Methods: This study was conducted in Department of Obstetrics and Gynaecology, Thanjavur medical college from August 2015 to August 2016. One hundred singleton pregnancies complicated by IUGR beyond 32 weeks were subjected for Doppler study of umbilical artery. Perinatal outcome in terms of baby outcome, birth weight, early neonatal death, admission in NICU and duration of admission in NICU were analysed.Results: The main indication of termination of pregnancy was oligohydramnios (70%). The other causes of termination were 8% for uncontrolled hypertension and 4 % for post term. 60 % were delivered vaginally and 40% by lower segment cesarean section. Various indication for LSCS were Non-reactive CTG, fetal distress, severe oligohydramnios and failed induction. 92% were delivered alive babies and 8% still born babies. Birth weight of the babies varied from 900gm to 2.5Kg. But patients with absent or reversed end diastolic flow in umbilical artery Doppler, 80% of the babies weighed less than 1.5Kg. Perinatal mortality in our study is 19% which includes 8% of intrapartum mortality and 11% of neonatal mortality and perinatal morbidity is 24%. When the diastolic flow in the umbilical artery is, absent or reversed, it is associated with increased perinatal mortality of 80%.Conclusions: The results of present study clearly demonstrated the efficacy of umbilical artery Doppler in predicting the fetal outcome. To improve the predictive value of this tool, a better method is needed to assess the wellbeing of the IUGR fetuses such as integrated antenatal test which combines BPP and Doppler study employing other vessels. 

Hematological changes in severe early onset growth-restricted fetuses with absent and reversed end-diastolic flow in the umbilical artery

2017 ◽  
Vol 45 (3) ◽  
Author(s):  
Franz Bahlmann ◽  
Ammar Al Naimi ◽  
Manfred Ossendorf ◽  
Monica Schmidt-Fittschen ◽  
Arne Willruth
Keyword(s):  
Early Onset ◽  
Umbilical Artery ◽  
Reverse Flow ◽  
Color Doppler ◽  
Venous Blood ◽  
Growth Restriction ◽  
Ductus Venosus ◽  
Diastolic Flow ◽  
Hemodynamic Compromise ◽  
Hematological Changes

AbstractBackground:Erythropoietin seems to play an important role in the regulation of fetal hypoxemia. The present prospective study was designed to determine if changes in erythropoietin levels can be found in fetuses with severe early-onset growth restriction and hemodynamic compromise.Methods and results:Erythropoietin, hemoglobin, hematocrit, platelet counts, normoblasts, lacate, arterial and venous blood gasses in the umbilical cord were determined in 42 fetuses with fetal growth restriction (IUGR) with absent (zero-flow) and 26 IUGR fetuses with retrograde end-diastolic flow (reverse-flow) in the umbilical artery. Color Doppler measurements were performed on the middle cerebral artery (PI) and ductus venosus [(S-a)/D and (S-a)/VConclusions:Fetuses with severe IUGR due to chronic placental insufficiency and absent or reversed flow in the umbilical artery show increased erythropoietin levels.

scholarly journals Sildenafil citrate therapy in absent end diastolic flow in umbilical artery in an early onset fetal growth restriction (FGR) fetus

2018 ◽  
Vol 7 (12) ◽  
pp. 5173
Author(s):  
Rana A. Choudhary ◽  
Khyati Patrawala ◽  
Kavita Desai ◽  
Kedar Ganla
Keyword(s):  
Blood Flow ◽  
Fetal Growth ◽  
Fetal Growth Restriction ◽  
Early Onset ◽  
Umbilical Artery ◽  
Fetal Outcome ◽  
Growth Restriction ◽  
Sildenafil Citrate ◽  
Optimal Time ◽  
Diastolic Flow

Fetal growth restriction (FGR), a pregnancy complication still poses as a challenge for obstetricians worldwide. This is because of its association with severe morbidity and mortality outcomes. Obstetrical management becomes a dilemma in determining the optimal time of delivery and weighing the risks of prematurity against the risks of a potentially hostile intrauterine environment. There may be placental insufficiency characterized by insufficient blood flow in the umbilical artery. This is termed as abnormal umbilical artery flow with absent or reversed end diastolic flow on Doppler USG. Worsening of this condition demands an earlier delivery of the fetus. Authors report a case of structurally normal foetus showing severe early onset FGR with absent end diastolic flow in umbilical artery on Doppler, which was managed using vaginal Sildenafil citrate. Sildenafil citrate led to improvement in uterine artery and umbilical artery Doppler parameters; thereby improving the utero-placental blood flow with a favorable fetal outcome at delivery. The gestation was prolonged by 51 days. Thus, Sildenafil citrate can be used as promising agent in early onset FGR in selected cases.

scholarly journals Role of Umbilical and Middle Cerebral Artery Doppler in Predicting Perinatal Outcome in Cases of Preeclampsia

2021 ◽  
Vol 8 (04) ◽  
pp. 195-198
Author(s):  
Kitty Elizabeth Mammen
Keyword(s):  
Blood Flow ◽  
Birth Weight ◽  
Middle Cerebral Artery ◽  
Cerebral Artery ◽  
Perinatal Outcome ◽  
Neonatal Death ◽  
Umbilical Artery ◽  
Diastolic Flow ◽  
Umbilical Artery Doppler

BACKGROUND One of the most common complications of pregnancy is preeclampsia, characterized by abnormal placental development, leading to inadequate uteroplacental blood flow. Doppler ultrasonography can pick up these abnormalities; thus, it is a useful tool to assess fetal outcome. Objective is to calculate the role of colour Doppler (umbilical and middle cerebral artery) in predicting the perinatal outcome. We wanted to evaluate the application of Doppler ultrasound in analysing the blood flow velocity waveform. METHODS This was a cross sectional study carried out between May 2010 - November 2012 in Obstetrics Department, Yenepoya Medical College, Karnataka, among 150 pregnant women with preeclampsia. RESULTS 49.3 % of patients belonged to 25 - 30 years, 58.7 % were primigravida, and 73.3 % and 26.7 % had mild and severe preeclampsia respectively. Patients with increased resistance umbilical artery Doppler - 63.8 % had babies < 2.5 Kg birth weight, 60.9 % Apgar < 7 at 5 minutes of birth and 67.5 % neonatal intensive care unit (NICU) admissions; absent end diastolic flow - all had birth weight < 2 Kg, 90 % Apgar < 7 at 5 minutes, 1 neonatal death and all required NICU admissions; reversal end diastolic flow - 1 neonatal death, all had birth weight < 2.5 Kg, an Apgar < 7 at 5 minutes and required NICU admission. Patients with abnormal Doppler in middle cerebral artery, 46.2 % were low birth weight and had Apgar < 7 at 5 minutes, 50 % required NICU admissions, but no perinatal mortality. CONCLUSIONS Doppler analysis helps in early detection of uteroplacental and fetoplacental changes and to take decisions for early interventions, like administration of steroids for fetal lung maturity and transferring preterm pregnancies to higher centres for better NICU facilities. Umbilical artery Doppler findings are slightly better predictors of adverse perinatal outcome than an abnormal middle cerebral artery. KEYWORDS Doppler, Preeclampsia, Perinatal Outcome, Umbilical Artery, Middle Cerebral Artery

Value of absent or retrograde end‐diastolic flow in fetal aorta and umbilical artery as a predictor of perinatal outcome in pregnancy‐induced hypertension

1993 ◽  
Vol 82 (12) ◽  
pp. 919-924 ◽  
Author(s):  
Marianne Eronen ◽  
Anneli Kari ◽  
Erkki Pesonen ◽  
Risto Kaaja ◽  
Eric Ivar Wallgren ◽  
...  
Keyword(s):  
Perinatal Outcome ◽  
Umbilical Artery ◽  
Pregnancy Induced Hypertension ◽  
Diastolic Flow ◽  
Induced Hypertension ◽  
In Pregnancy

scholarly journals P05.27: Abnormal end-diastolic flow pattern in the umbilical artery and perinatal mortality

2004 ◽  
Vol 24 (3) ◽  
pp. 302-302
Author(s):  
A. Cromi ◽  
S. Lanz ◽  
F. Ghezzi ◽  
S. Zefiro ◽  
S. Tomera ◽  
...  
Keyword(s):  
Flow Pattern ◽  
Perinatal Mortality ◽  
Umbilical Artery ◽  
Diastolic Flow

scholarly journals P05.26: Prognostic factors for survival in fetuses with reverse end-diastolic flow on Doppler umbilical artery velocimetry

2004 ◽  
Vol 24 (3) ◽  
pp. 302-302
Author(s):  
S. Lanz ◽  
A. Cromi ◽  
F. Ghezzi ◽  
E. Di Naro ◽  
V. Bergamini ◽  
...  
Keyword(s):  
Prognostic Factors ◽  
Umbilical Artery ◽  
Diastolic Flow

scholarly journals OP13.10: Perinatal outcome of 127 consecutive fetuses with single umbilical artery

2008 ◽  
Vol 32 (3) ◽  
pp. 353-353
Author(s):  
F. Vinals ◽  
S. Diaz ◽  
R. Naveas ◽  
A. Giuliano
Keyword(s):  
Perinatal Outcome ◽  
Umbilical Artery ◽  
Single Umbilical Artery
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