Simulating Family Histories of Cancer

2003 ◽  
Vol 8 (4-5) ◽  
pp. 455-474
Author(s):  
Chris D. Bajdik ◽  
Richard P. Gallagher
Keyword(s):  
Family Histories

The Use of Medical Record Linkage for Population and Genetic Studies

1969 ◽  
Vol 08 (01) ◽  
pp. 07-11 ◽  
Author(s):  
H. B. Newcombe
Keyword(s):  
Record Linkage ◽  
Large Scale ◽  
Medical Record Linkage ◽  
Canadian Province ◽  
Genetic Studies ◽  
Parental Characteristics ◽  
Family Histories ◽  
The Family ◽  
Large Populations ◽  
Machine Readable

Methods are described for deriving personal and family histories of birth, marriage, procreation, ill health and death, for large populations, from existing civil registrations of vital events and the routine records of ill health. Computers have been used to group together and »link« the separately derived records pertaining to successive events in the lives of the same individuals and families, rapidly and on a large scale. Most of the records employed are already available as machine readable punchcards and magnetic tapes, for statistical and administrative purposes, and only minor modifications have been made to the manner in which these are produced.As applied to the population of the Canadian province of British Columbia (currently about 2 million people) these methods have already yielded substantial information on the risks of disease: a) in the population, b) in relation to various parental characteristics, and c) as correlated with previous occurrences in the family histories.

Marguerite Wood and Margaret Simpson, two pioneering Scottish women

2019 ◽  
Vol 41 (1) ◽  
pp. 108-118
Author(s):  
David J. Breeze ◽  
Rosalind K. Marshall ◽  
Ian Ralston
Keyword(s):  
Family Histories ◽  
The Family ◽  
Ancient Monuments

In the 1920s and 1930s Marguerite Wood and Margaret Simpson collaborated with James Richardson, Inspector of Ancient Monuments for Scotland, in writing guide-books to several medieval monuments in state care. The involvement of women in such activities was unusual for the time. The family histories and careers of these two pioneering Scottish women are investigated in order to explain their participation, and their activities are placed in the wider context of the emerging professionalism of women in history and archaeology in Scotland at this time.

scholarly journals Family Ties: Women's Work and Family Histories and their Association with Incomes in Later Life in the UK

2010 ◽  
Vol 40 (1) ◽  
pp. 41-69 ◽  
Author(s):  
TOM SEFTON ◽  
MARIA EVANDROU ◽  
JANE FALKINGHAM
Keyword(s):  
Older Women ◽  
Close Association ◽  
Later Life ◽  
Work And Family ◽  
Positive Finding ◽  
Work History ◽  
Family Histories ◽  
Public Transfers ◽  
Work Histories ◽  
Personal Incomes

AbstractThis article examines the relationship between the family and work histories of older women and their personal incomes in later life, using retrospective data from the first 15 waves of the British Household Panel Survey. The association between women's family histories and their incomes later in life are relatively weak, explaining only a small proportion of the overall variation in older women's incomes. Divorce, early widowhood and re-marriage are not associated with any significant differences in older women's incomes, while motherhood is only associated with a small reduction in incomes later in life. While there are significant differences in the work histories of older women with different family histories, this translates into relatively small differences in their personal incomes, because the types of employment career pursued by most women are not associated with significantly higher retirement incomes and because public transfers dampen work history-related differentials, especially for widows. On the one hand, this could be seen as a positive finding in that the ‘pension penalty’ associated with life-course events such as motherhood and divorce is not as severe as often anticipated. On the other hand, the main reason for this is that the pension returns to working longer are relatively low, particularly for women with few qualifications. The analysis suggests that women retiring over the next two decades are unlikely to benefit significantly from the additional years they have spent in employment, because most of this increase has been in part-time employment. The article highlights the tensions between two objectives: rewarding work, and protecting the most vulnerable, such as carers, long-term disabled and unemployed. Resolving this dilemma involves moving away from a close association between pension entitlements and work history and towards universal entitlement based on a citizen's pension.

FAMILY TENSION AS A CAUSE OF COLIC IN INFANTS

PEDIATRICS ◽  
1956 ◽  
Vol 18 (5) ◽  
pp. 835-836
Author(s):  
John C. Cobb
Keyword(s):  
Family History ◽  
Allergic Disease ◽  
Family Members ◽  
Clinical Impression ◽  
Family Histories ◽  
The Family

A study of colic in infancy was undertaken as part of the Yale Rooming-In Project. The longitudinal records of 98 infants who were study subjects were analyzed with respect to incidence, duration, and severity of colic. Forty-eight of the infants were classified as fussy or colicky and 50 as contented. Because I had formed the clinical impression that allergy was an important contributing factor in the causation of colic, careful family histories were taken for all of these infants with particular attention to allergic disease in any member of either parent's family. An adequate family history was obtained in 95 of these infants. These data were analyzed both according to the incidence of allergic disease and according to the severity of allergic disease in family members. Among the relatives of the 45 "fussy" or "colicky" infants 7.3 per cent had severe allergy, 17.7 pen cent had mild allergy and 74 per cent had little or no allergy. Among the relatives of the 50 contented infants 7.6 per cent had severe allergy, 14.7 per cent had mild allergy and 77 per cent had no allergy. The family histories included a total of 957 relatives. The 45 families of the babies who were fussy or colicky were divided as follows as to amount of allergy among the relatives. In 7 families there was much allergy, in 30 families there was some allergy and in 8 families there was little or no allergy. The [See Table I in Source PDF] families of the 50 contented infants were divided as follows, in 7 families there was much allergy, in 33 there was some allergy and in 10 there was little on no allergy.

CULTIVATING THE FAMILY

PEDIATRICS ◽  
1975 ◽  
Vol 55 (5) ◽  
pp. 639-639
Author(s):  
Lewis Mumford
Keyword(s):  
Family Tree ◽  
Family Histories ◽  
The Family

The culture of the family requires time, patience, and fuller participation by all its members; and for its personal sustenance, interest must be awakened on its spiritual side: its history and biography. The antiquarian search for a family tree is too often the lowest snobbism; but the actual planting and cultivating of the family tree is a different matter. That is worthy of everyone's highest skill and immediate attention. . . . So for us the widespread keeping of family records is at least mechanically an easy job: spiritually it will require immense effort, before we pour into the work all the love and skill that it demands. The writing of journals, psychological records, and family histories beginning with the here and now should be one of the most grateful tasks for parents: the gathering of souvenirs, memorabilia, drawings, the recording of anecdotes and stories—all these things will build up that past which will form a bridge, over the most turbid autumnal torrent, to a firmer, finer future.

REPRODUCTIVE FAILURE IN FAMILIES OF PATIENTS WITH IDIOPATHIC DEVELOPMENTAL RETARDATION

PEDIATRICS ◽  
1964 ◽  
Vol 33 (1) ◽  
pp. 100-105
Author(s):  
Robert L. Tips ◽  
George Smith ◽  
Donald L. Meyer
Keyword(s):  
Genetic Factors ◽  
Fetal Loss ◽  
Reproductive Rate ◽  
Reproductive Failure ◽  
Comparison Study ◽  
Clinical Genetic ◽  
Abnormal Pregnancy ◽  
Developmental Retardation ◽  
Family Histories ◽  
The Family

1. The family histories of 30 patients with idiopathic developmental retardation were analyzed with respect to pregnancy records of nonaffected female kindred. Comparison was made with data from the family histories of 27 similarly ascertained control patients. 2. The mothers and maternal aunts of retardates were found to have abnormal pregnancy records, i.e., a markedly decreased reproductive rate and increased fetal loss (reproductive failure). Similar findings were not noted in the histories of the maternal grandmothers or other females in the families. 3. The comparison study suggests genetic factors as an influence on reproduction in the maternal families of retardates but their nature remains unknown. 4. The utilization of these findings in clinical genetic counseling is briefly discussed.

Genetic Family Histories: An Aid to Social Work Assessment

1993 ◽  
Vol 74 (4) ◽  
pp. 195-206 ◽  
Author(s):  
Barbara Bernhardt ◽  
Julia B. Rauch
Keyword(s):  
Social Work ◽  
Genetic Services ◽  
Case Scenario ◽  
Worst Case ◽  
Worst Case Scenario ◽  
Family Histories ◽  
Work Assessment ◽  
Focus Depth ◽  
Service Training ◽  
Agency Design

The focus, depth, and use of genetic family histories vary depending on the agency purpose and the client's presenting problem. Failure to obtain genetic family histories can result in inaccurate assessment and incomplete or misdirected services. In the worst-case scenario, failure to obtain such information and to advise clients of available genetic services are potential grounds for malpractice and wrongful-adoption suits. The authors discuss approaches to obtaining and recording genetic family histories and present criteria for referral to genetic services. The authors recommend that agency administrators consider consulting with a genetic professional to determine the appropriate focus of genetic family histories within the agency, design a protocol, and arrange in-service training in use of the protocol.

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