Fabrication and characterization of hydroxypropyl guar-poly (vinyl alcohol)-nano hydroxyapatite composite hydrogels for bone tissue engineering

2018 ◽  
Vol 29 (17) ◽  
pp. 2083-2105 ◽  
Author(s):  
Anil Parameswaran-Thankam ◽  
Qudes Al-Anbaky ◽  
Zeiyad Al-karakooly ◽  
Ambar B. RanguMagar ◽  
Bijay P. Chhetri ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Bone Tissue Engineering ◽  
Bone Tissue ◽  
Vinyl Alcohol ◽  
Poly Vinyl Alcohol ◽  
Composite Hydrogels ◽  
Hydroxypropyl Guar ◽  
Hydroxyapatite Composite ◽  
Fabrication And Characterization

scholarly journals Dual Network Composites of Poly(vinyl alcohol)-Calcium Metaphosphate/Alginate with Osteogenic Ions for Bone Tissue Engineering in Oral and Maxillofacial Surgery

2021 ◽  
Vol 8 (8) ◽  
pp. 107
Author(s):  
Lilis Iskandar ◽  
Lucy DiSilvio ◽  
Jonathan Acheson ◽  
Sanjukta Deb
Keyword(s):  
Tissue Engineering ◽  
Bone Tissue Engineering ◽  
Bone Tissue ◽  
Vinyl Alcohol ◽  
Maxillofacial Surgery ◽  
Bone Defects ◽  
Bone Tissue Regeneration ◽  
Poly Vinyl Alcohol ◽  
Oral And Maxillofacial Surgery

Despite considerable advances in biomaterials-based bone tissue engineering technologies, autografts remain the gold standard for rehabilitating critical-sized bone defects in the oral and maxillofacial (OMF) region. A majority of advanced synthetic bone substitutes (SBS’s) have not transcended the pre-clinical stage due to inferior clinical performance and translational barriers, which include low scalability, high cost, regulatory restrictions, limited advanced facilities and human resources. The aim of this study is to develop clinically viable alternatives to address the challenges of bone tissue regeneration in the OMF region by developing ‘dual network composites’ (DNC’s) of calcium metaphosphate (CMP)—poly(vinyl alcohol) (PVA)/alginate with osteogenic ions: calcium, zinc and strontium. To fabricate DNC’s, single network composites of PVA/CMP with 10% (w/v) gelatine particles as porogen were developed using two freeze–thawing cycles and subsequently interpenetrated by guluronate-dominant sodium alginate and chelated with calcium, zinc or strontium ions. Physicochemical, compressive, water uptake, thermal, morphological and in vitro biological properties of DNC’s were characterised. The results demonstrated elastic 3D porous scaffolds resembling a ‘spongy bone’ with fluid absorbing capacity, easily sculptable to fit anatomically complex bone defects, biocompatible and osteoconductive in vitro, thus yielding potentially clinically viable for SBS alternatives in OMF surgery.

Fabrication and characterization of Spinacia oleracea extract incorporated alginate/carboxymethyl cellulose microporous scaffold for bone tissue engineering

2020 ◽  
Vol 156 ◽  
pp. 430-437 ◽  
Author(s):  
Govindasamy Sharmila ◽  
Chandrasekaran Muthukumaran ◽  
Shanmugam Kirthika ◽  
Sundarapandian Keerthana ◽  
Narasimhan Manoj Kumar ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Bone Tissue Engineering ◽  
Bone Tissue ◽  
Carboxymethyl Cellulose ◽  
Spinacia Oleracea ◽  
Fabrication And Characterization

scholarly journals Fabrication and characterization of biomimetic collagen–apatite scaffolds with tunable structures for bone tissue engineering

2013 ◽  
Vol 9 (7) ◽  
pp. 7308-7319 ◽  
Author(s):  
Zengmin Xia ◽  
Xiaohua Yu ◽  
Xi Jiang ◽  
Harold D. Brody ◽  
David W. Rowe ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Bone Tissue Engineering ◽  
Bone Tissue ◽  
Fabrication And Characterization
Sign in / Sign up

Export Citation Format

Share Document